このエントリーをはてなブックマークに追加
ID 61428
JaLCDOI
FullText URL
75_1_9.pdf 4.65 MB
Author
Gobara, Hideo Division of Medical Informatics, Okayama University Hospital ORCID Kaken ID publons researchmap
Yamamoto, Akira Department of Diagnostic and Interventional Radiology, Osaka City University Graduate School of Medicine
Komakic, Toshiyuki Department of Radiology, Okayama University Hospital
Kitayama, Toshiaki Department of Radiology, Otemae Hospital
Sakurai, Jun Center for Innovative Clinical Medicine, Okayama University Hospital
Iguchi, Toshihiro Department of Radiology, Okayama University Hospital
Matsui, Yusuke Department of Radiology, Okayama University Hospital
Uka, Mayu Department of Radiology, Okayama University Hospital
Tomita, Koji Department of Radiology, Okayama University Hospital
Hiraki, Takao Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID publons researchmap
Kanazawa, Susumu Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Kaken ID publons
Abstract
To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base. The discolored area of cut surface along the device was evaluated in 5 application-time groups (5 , 10 , 15 , 20, or 25 seconds). An ex vivo experiment was performed to determine an ablation algorithm with an appropriate application time by comparison with radiofrequency ablation (RFA) results. Thereafter, an in vivo experiment was performed to verify the algorithm’s feasibility. In the ex vivo model, the cut surface demonstrated different amounts of discolored area according to the application time. The total discolored area in the 20-seconds group was similar to that by RFA. In the in vivo model, the liver did not bleed, the total discolored area was similar to that ex vivo, and coagulation necrosis was confirmed by photomicrograph. Needle tract ablation can be per-formed using the experimental device and electrosurgical device.
Keywords
needle tract ablation
cryoablation
electrosurgical device
animal
liver
Amo Type
Original Article
Publication Title
Acta Medica Okayama
Published Date
2021-02
Volume
volume75
Issue
issue1
Publisher
Okayama University Medical School
Start Page
9
End Page
14
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
英語
Copyright Holders
CopyrightⒸ 2021 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID