FullText URL fulltext.pdf
Author Ichihara, Eiki| Mitsuhashi, Toshiharu| Tsuge, Mitsuru| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Hagiya, Hideharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu|
Keywords clinical outcome covid-19 localized respiratory symptom severe disease risk systemic symptom
Published Date 2025-05-27
Publication Title Cureus
Volume volume17
Issue issue5
Publisher Springer Science and Business Media LLC
Start Page e84919
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2025 Ichihara et al.
File Version publisher
PubMed ID 40575188
DOI 10.7759/cureus.84919
Related Url isVersionOf https://doi.org/10.7759/cureus.84919
FullText URL fulltext.pdf
Author Obara, Takafumi| Nojima, Tsuyoshi| Matsumoto, Naomi| Tsukahara, Kohei| Hongo, Takashi| Yumoto, Tetsuya| Yorifuji, Takashi| Nakao, Atsunori| Naito, Hiromichi|
Keywords Drowning Out-of-hospital cardiac arrest Cardiopulmo naryresuscitation Child Asphyxia
Published Date 2026-08
Publication Title Resuscitation
Volume volume225
Publisher Elsevier BV
Start Page 111049
ISSN 0300-9572
NCID AA00817253
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©2026 The Author(s).
File Version publisher
PubMed ID 41819340
DOI 10.1016/j.resuscitation.2026.111049
Web of Science KeyUT 001808362200001
Related Url isVersionOf https://doi.org/10.1016/j.resuscitation.2026.111049
JaLCDOI 10.18926/AMO/70854
FullText URL 80_3_185.pdf
Author Kubo, Takuya| Tsukahara, Kohei| Hongo, Takashi| Obara, Takafumi| Kosaki, Yoshinori| Nojima, Tsuyoshi| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Abstract Women are less likely than men to receive timely defibrillation during out-of-hospital cardiac arrest. We investigated whether using a simulator that is visually modified to resemble a female affects learners’ attitudes, knowledge, and performance in basic life support (BLS) training. In a BLS simulation training, first-year medical students (n=220) used a standard gender-neutral simulator (control group) or a modified simulator with a female-like appearance (intervention group). Pre- and post-training questionnaires concerning attitudes and knowledge plus a post-training skills evaluation assessed the students’ training outcomes. The intervention group initiated chest compressions significantly faster than the control group (33.1 vs. 39.8 sec, p<0.01) and achieved a significantly higher rate of correct AED pad placement (64.2% vs. 38.5%, p<0.01). While performing the resuscitation on the female-appearing manikin, the intervention group showed significantly greater increases in self-efficacy (p<0.01) and larger decreases in discomfort about removing the patient’s clothes (p<0.01). They were also significantly more likely to recognize that chest compressions can be performed (p=0.016) and AED pads can be applied (p=0.015) without removing the patient’s underwear. Using a female-appearing simulator in BLS training was thus associated with faster chest compression initiation, more accurate AED pad placement, and improved gender-sensitive attitudes and knowledge.
Keywords resuscitation basic life support female simulator medical education gender bias
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-06
Volume volume80
Issue issue3
Publisher Okayama University Medical School
Start Page 185
End Page 193
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 42374751
Web of Science KeyUT 001812989700004
FullText URL fulltext.pdf
Author Tokioka, Kohei| Nojima, Tsuyoshi| Hirayama, Takahiro| Hongo, Takashi| Obara, Takafumi| Ageta, Kohei| Igawa, Takuro| Aokage, Toshiyuki| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Published Date 2026-07
Publication Title Surgery
Volume volume195
Publisher Elsevier BV
Start Page 110231
ISSN 0039-6060
NCID AA00853880
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Authors.
File Version publisher
PubMed ID 42114235
DOI 10.1016/j.surg.2026.110231
Web of Science KeyUT 001768042400001
Related Url isVersionOf https://doi.org/10.1016/j.surg.2026.110231
JaLCDOI 10.18926/AMO/70458
FullText URL 80_2_153.pdf
Author Ueda, Yoshiyuki| Yumoto, Tetsuya| Hongo, Takashi| Obara, Takafumi| Nojima, Tsuyoshi| Tsukahara, Kohei| Hasegawa, Kosei| Futagawa, Natsuko| Naito, Hiromichi| Nakao, Atsunori|
Abstract Adrenal crisis is a life-threatening endocrine emergency that can progress within hours despite a prior diagnosis and maintenance therapy. We describe a fatal influenza-triggered adrenal crisis in two patients: a child with panhypopituitarism and an adult with prior pituitary surgery, both presenting in cardiac arrest. Despite resuscitation and intravenous hydrocortisone, a fatal hypoxic-ischemic injury or multiorgan failure occurred. These cases highlight the fulminant course of an adrenal crisis and underscore the importance of early recognition, clinician awareness, prompt parenteral hydrocortisone administration, and reinforcement of education for patients, caregivers, and healthcare providers to improve preparedness and prevent avoidable deaths.
Keywords adrenal insufficiency cardiac arrest hydrocortisone influenza shock
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 153
End Page 157
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 42025437
Web of Science KeyUT 001761342100009
FullText URL fulltext.pdf
Author Tokioka, Kohei| Nojima, Tsuyoshi| Matsuo, Ippei| Tsukahara, Kohei| Nakao, Atsunori|
Keywords acute dystonia aripiprazole drug-induced movement disorder oculogyric crisis
Published Date 2026-02
Publication Title Clinical Case Reports
Volume volume14
Issue issue2
Publisher Wiley
Start Page e72067
ISSN 2050-0904
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41710502
DOI 10.1002/ccr3.72067
Related Url isVersionOf https://doi.org/10.1002/ccr3.72067
FullText URL fulltext.pdf
Author Ueda, Yoshiyuki| Nojima, Tsuyoshi| Obara, Takafumi| Hongo, Takashi| Yumoto, Tetsuya| Tsukahara, Kohei| Yorifuji, Takashi| Nakao, Atsunori| Naito, Hiromichi|
Keywords Cardiac arrest Cardiopulmonary resuscitation Cerebral hemorrhage Stroke Subarachnoid hemorrhage
Published Date 2025-11
Publication Title Resuscitation Plus
Volume volume26
Publisher Elsevier BV
Start Page 101145
ISSN 2666-5204
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 41312446
DOI 10.1016/j.resplu.2025.101145
Web of Science KeyUT 001619366500001
Related Url isVersionOf https://doi.org/10.1016/j.resplu.2025.101145
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Author Morikawa, Tomoki| Obara, Takafumi| Nojima, Tsuyoshi| Tokioka, Kohei| Nakao, Atsunori| Tsukahara, Kohei|
Keywords amusement parks brain injuries carotid artery dissection stroke vertebral artery dissection
Published Date 2025-01
Publication Title Pediatrics International
Volume volume67
Issue issue1
Publisher Wiley
Start Page e70221
ISSN 1328-8067
NCID AA11320483
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 41045005
DOI 10.1111/ped.70221
Web of Science KeyUT 001587547500001
Related Url isVersionOf https://doi.org/10.1111/ped.70221
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Author Jinno, Shunta| Hongo, Takashi| Obara, Takafumi| Nojima, Tsuyoshi| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Keywords brain death heart arrest helium
Published Date 2025-04-28
Publication Title JMA Journal
Volume volume8
Issue issue2
Publisher Japan Medical Association
Start Page 650
End Page 653
ISSN 2433-3298
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Japan Medical Association
File Version publisher
PubMed ID 40416025
DOI 10.31662/jmaj.2024-0395
Web of Science KeyUT 001450822700001
Related Url isVersionOf https://doi.org/10.31662/jmaj.2024-0395
FullText URL fulltext.pdf
Author Obara, Takafumi| Naito, Hiromichi| Matsumoto, Naomi| Tsukahara, Kohei| Hongo, Takashi| Nojima, Tsuyoshi| Yumoto, Tetsuya| Yorifuji, Takashi| Nakao, Atsunori|
Keywords Cardiopulmonary resuscitation Out-of-hospital Pediatrics Artificial respiration COVID-19 pandemic
Published Date 2025-10
Publication Title Resuscitation
Volume volume215
Publisher Elsevier BV
Start Page 110706
ISSN 0300-9572
NCID AA00817253
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40619060
DOI 10.1016/j.resuscitation.2025.110706
Web of Science KeyUT 001534174600001
Related Url isVersionOf https://doi.org/10.1016/j.resuscitation.2025.110706
JaLCDOI 10.18926/AMO/69147
FullText URL 79_4_221.pdf
Author Yumoto, Tetsuya| Naito, Hiromichi| Hongo, Takashi| Obara, Takafumi| Kosaki, Yoshinori| Ageta, Kohei| Nojima, Tsuyoshi| Tsukahara, Kohei| Nakao, Atsunori|
Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) has evolved into a life-saving therapy for select cardiac arrest patients, yet a growing body of evidence suggests it also holds promise as a bridge to organ donation in non-survivors. This review explores the clinical outcomes, ethical complexities, and evolving policies surrounding organ donation after ECPR. We summarize recent international and Japanese data demonstrating favorable graft function from ECPR donors, with the exception of lung transplantation. The ethical challenges — particularly those involving brain death determination on extracorporeal membrane oxygenation and adherence to the dead donor rule — are discussed in the context of Japan’s recent regulatory reforms. Additionally, we highlight the importance of structured end-of-life communication through multidisciplinary team meetings in facilitating ethically sound transitions from rescue efforts to donation pathways. Moving forward, improvements in donor management, standardized legal frameworks, and public and professional education are essential to optimizing the life-saving and life-giving potential of ECPR.
Keywords brain death end-of-life care ethical dilemmas extracorporeal cardiopulmonary resuscitation
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2025-08
Volume volume79
Issue issue4
Publisher Okayama University Medical School
Start Page 221
End Page 229
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 40859438
Web of Science KeyUT 001566286400001
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Obara, Takafumi| Hongo, Takashi| Nojima, Tsuyoshi| Tsukahara, Kohei| Hisamura, Masaki| Nakao, Atsunori| Yorifuji, Takashi| Naito, Hiromichi|
Keywords Ambulance diversion Bed occupancy Brain death Emergency medical services Intensive care units Organ donation
Published Date 2025-04-12
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 12633
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40221631
DOI 10.1038/s41598-025-97198-7
Web of Science KeyUT 001466042000027
Related Url isVersionOf https://doi.org/10.1038/s41598-025-97198-7
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Obara, Takafumi| Hongo, Takashi| Iida, Atsuyoshi| Tsukahara, Kohei| Katsura, Morihiro| Kondo, Yutaka| Yasuda, Hideto| Kushimoto, Shigeki| Yorifuji, Takashi| Naito, Hiromichi| Nakao, Atsunori| SHIPPs Study Group|
Keywords Abdominal injuries Blood transfusions Hemoglobin Hemostasis Shock index
Published Date 2025-03-12
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 8502
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40074821
DOI 10.1038/s41598-025-92673-7
Web of Science KeyUT 001443941100009
Related Url isVersionOf https://doi.org/10.1038/s41598-025-92673-7
FullText URL fulltext.pdf
Author Hiraoka, Tomohiro| Obara, Takafumi| Matsumoto, Naomi| Tsukahara, Kohei| Hongo, Takashi| Nojima, Tsuyoshi| Hisamura, Masaki| Yumoto, Tetsuya| Nakao, Atsunori| Yorifuji, Takashi| Naito, Hiromichi|
Keywords Retrospective cohort study Injury recurrence Injury prevention
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76403-z|
Published Date 2024-10-21
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 24716
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39433855
DOI 10.1038/s41598-024-76403-z
Web of Science KeyUT 001339991400047
Related Url isVersionOf https://doi.org/10.1038/s41598-024-76403-z
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Hongo, Takashi| Obara, Takafumi| Ageta, Kohei| Aokage, Toshiyuki| Tsukahara, Kohei| Nakao, Atsunori| Naito, Hiromichi|
Keywords clinical conference end-of-life care ICU rounds multidisciplinary team meetings
Published Date 2024-07-24
Publication Title Journal of Clinical Medicine
Volume volume13
Issue issue15
Publisher MDPI
Start Page 4324
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39124591
DOI 10.3390/jcm13154324
Web of Science KeyUT 001287177900001
Related Url isVersionOf https://doi.org/10.3390/jcm13154324
FullText URL fulltext.pdf
Author Tsuge, Mitsuru| Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Hagiya, Hideharu| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu|
Keywords novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date 2024-07-31
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue15
Publisher MDPI
Start Page 8370
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39125944
DOI 10.3390/ijms25158370
Web of Science KeyUT 001286890700001
Related Url isVersionOf https://doi.org/10.3390/ijms25158370
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Tsukahara, Kohei| Obara, Takafumi| Hongo, Takashi| Nojima, Tsuyoshi| Naito, Hiromichi| Nakao, Atsunori|
Keywords Brain death Cardiopulmonary resuscitation Extracorporeal membrane oxygenation Organ transplantation Out-of-hospital cardiac arrest Tissue and organ procurement
Note The version of record of this article, first published in Critical Care, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13054-024-04949-5|
Published Date 2024-05-13
Publication Title Critical Care
Volume volume28
Issue issue1
Publisher BMC
Start Page 160
ISSN 1364-8535
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38741176
DOI 10.1186/s13054-024-04949-5
Web of Science KeyUT 001221675100001
Related Url isVersionOf https://doi.org/10.1186/s13054-024-04949-5
FullText URL fulltext.pdf
Author Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Yamada, Haruto| Takata, Ichiro| Hagiya, Hideharu| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Toyooka, Shinichi| Tsukahara, Kohei| Aokage, Toshiyuki| Tsukahara, Hirokazu| Kiura, Katsuyuki| Maeda, Yoshinobu|
Published Date 2023-10-26
Publication Title PLoS ONE
Volume volume18
Issue issue10
Publisher Public Library of Science
Start Page e0287501
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Ichihara et al.
File Version publisher
PubMed ID 37883347
DOI 10.1371/journal.pone.0287501
Web of Science KeyUT 001094123400028
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0287501
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Hongo, Takashi| Koide, Yasuhiro| Obara, Takafumi| Tsukahara, Kohei| Naito, Hiromichi| Nakao, Atsunori|
Keywords Emergency service Informed consent Radiation Treatment refusal
Note The version of record of this article, first published in BMC Medical Ethics, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12910-023-00962-5|
Published Date 2023-10-04
Publication Title BMC Medical Ethics
Volume volume24
Issue issue1
Publisher BMC
Start Page 80
ISSN 1472-6939
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37794408
DOI 10.1186/s12910-023-00962-5
Web of Science KeyUT 001080177500004
Related Url isVersionOf https://doi.org/10.1186/s12910-023-00962-5
JaLCDOI 10.18926/AMO/65755
FullText URL 77_4_429.pdf
Author Sasanami, Misa| Iida, Atsuyoshi| Iwamuro, Masaya| Hirai, Ryousuke| Obara, Takashi| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Abstract Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
Keywords chest pain dysphagia esophageal dissection hematemesis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 429
End Page 431
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635144
Web of Science KeyUT 001163659800012