Tsukahara, Kohei - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Revisiting Adrenal Crisis Triggered by Influenza Infection: Lessons from Two Fatal Cases

JaLCDOI	10.18926/AMO/70458
FullText URL	80_2_153.pdf
Author	Ueda, Yoshiyuki\| Yumoto, Tetsuya\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Hasegawa, Kosei\| Futagawa, Natsuko\| Naito, Hiromichi\| Nakao, Atsunori\|
Abstract	Adrenal crisis is a life-threatening endocrine emergency that can progress within hours despite a prior diagnosis and maintenance therapy. We describe a fatal influenza-triggered adrenal crisis in two patients: a child with panhypopituitarism and an adult with prior pituitary surgery, both presenting in cardiac arrest. Despite resuscitation and intravenous hydrocortisone, a fatal hypoxic-ischemic injury or multiorgan failure occurred. These cases highlight the fulminant course of an adrenal crisis and underscore the importance of early recognition, clinician awareness, prompt parenteral hydrocortisone administration, and reinforcement of education for patients, caregivers, and healthcare providers to improve preparedness and prevent avoidable deaths.
Keywords	adrenal insufficiency cardiac arrest hydrocortisone influenza shock
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2026-04
Volume	volume80
Issue	issue2
Publisher	Okayama University Medical School
Start Page	153
End Page	157
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2026 by Okayama University Medical School
File Version	publisher
Refereed	True

Oculogyric Crisis During Chronic Aripiprazole Therapy: A Diagnostic Challenge in the Emergency Department

FullText URL	fulltext.pdf
Author	Tokioka, Kohei\| Nojima, Tsuyoshi\| Matsuo, Ippei\| Tsukahara, Kohei\| Nakao, Atsunori\|
Keywords	acute dystonia aripiprazole drug-induced movement disorder oculogyric crisis
Published Date	2026-02
Publication Title	Clinical Case Reports
Volume	volume14
Issue	issue2
Publisher	Wiley
Start Page	e72067
ISSN	2050-0904
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2026 The Author(s).
File Version	publisher
PubMed ID	41710502
DOI	10.1002/ccr3.72067
Related Url	isVersionOf https://doi.org/10.1002/ccr3.72067

Characteristics of out-of-hospital cardiac arrest due to cerebrovascular disorders: a nationwide, retrospective, observational study

FullText URL	fulltext.pdf
Author	Ueda, Yoshiyuki\| Nojima, Tsuyoshi\| Obara, Takafumi\| Hongo, Takashi\| Yumoto, Tetsuya\| Tsukahara, Kohei\| Yorifuji, Takashi\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Cardiac arrest Cardiopulmonary resuscitation Cerebral hemorrhage Stroke Subarachnoid hemorrhage
Published Date	2025-11
Publication Title	Resuscitation Plus
Volume	volume26
Publisher	Elsevier BV
Start Page	101145
ISSN	2666-5204
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41312446
DOI	10.1016/j.resplu.2025.101145
Web of Science KeyUT	001619366500001
Related Url	isVersionOf https://doi.org/10.1016/j.resplu.2025.101145

Pediatric stroke risk and neurotrauma from roller coasters in amusement parks

FullText URL	fulltext.pdf
Author	Morikawa, Tomoki\| Obara, Takafumi\| Nojima, Tsuyoshi\| Tokioka, Kohei\| Nakao, Atsunori\| Tsukahara, Kohei\|
Keywords	amusement parks brain injuries carotid artery dissection stroke vertebral artery dissection
Published Date	2025-01
Publication Title	Pediatrics International
Volume	volume67
Issue	issue1
Publisher	Wiley
Start Page	e70221
ISSN	1328-8067
NCID	AA11320483
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	41045005
DOI	10.1111/ped.70221
Web of Science KeyUT	001587547500001
Related Url	isVersionOf https://doi.org/10.1111/ped.70221

Successful Transplantation of Multiple Organs from Donor after Helium Asphyxiation: First Case Report in Japan

FullText URL	fulltext.pdf
Author	Jinno, Shunta\| Hongo, Takashi\| Obara, Takafumi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	brain death heart arrest helium
Published Date	2025-04-28
Publication Title	JMA Journal
Volume	volume8
Issue	issue2
Publisher	Japan Medical Association
Start Page	650
End Page	653
ISSN	2433-3298
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© Japan Medical Association
File Version	publisher
PubMed ID	40416025
DOI	10.31662/jmaj.2024-0395
Web of Science KeyUT	001450822700001
Related Url	isVersionOf https://doi.org/10.31662/jmaj.2024-0395

Compression only CPR and mortality in pediatric out-of-hospital cardiac arrest during COVID-19 pandemic

FullText URL	fulltext.pdf
Author	Obara, Takafumi\| Naito, Hiromichi\| Matsumoto, Naomi\| Tsukahara, Kohei\| Hongo, Takashi\| Nojima, Tsuyoshi\| Yumoto, Tetsuya\| Yorifuji, Takashi\| Nakao, Atsunori\|
Keywords	Cardiopulmonary resuscitation Out-of-hospital Pediatrics Artificial respiration COVID-19 pandemic
Published Date	2025-10
Publication Title	Resuscitation
Volume	volume215
Publisher	Elsevier BV
Start Page	110706
ISSN	0300-9572
NCID	AA00817253
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2025 The Author(s).
File Version	publisher
PubMed ID	40619060
DOI	10.1016/j.resuscitation.2025.110706
Web of Science KeyUT	001534174600001
Related Url	isVersionOf https://doi.org/10.1016/j.resuscitation.2025.110706

Organ Donation after Extracorporeal Cardiopulmonary Resuscitation: Clinical and Ethical Perspectives

JaLCDOI	10.18926/AMO/69147
FullText URL	79_4_221.pdf
Author	Yumoto, Tetsuya\| Naito, Hiromichi\| Hongo, Takashi\| Obara, Takafumi\| Kosaki, Yoshinori\| Ageta, Kohei\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Nakao, Atsunori\|
Abstract	Extracorporeal cardiopulmonary resuscitation (ECPR) has evolved into a life-saving therapy for select cardiac arrest patients, yet a growing body of evidence suggests it also holds promise as a bridge to organ donation in non-survivors. This review explores the clinical outcomes, ethical complexities, and evolving policies surrounding organ donation after ECPR. We summarize recent international and Japanese data demonstrating favorable graft function from ECPR donors, with the exception of lung transplantation. The ethical challenges — particularly those involving brain death determination on extracorporeal membrane oxygenation and adherence to the dead donor rule — are discussed in the context of Japan’s recent regulatory reforms. Additionally, we highlight the importance of structured end-of-life communication through multidisciplinary team meetings in facilitating ethically sound transitions from rescue efforts to donation pathways. Moving forward, improvements in donor management, standardized legal frameworks, and public and professional education are essential to optimizing the life-saving and life-giving potential of ECPR.
Keywords	brain death end-of-life care ethical dilemmas extracorporeal cardiopulmonary resuscitation
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2025-08
Volume	volume79
Issue	issue4
Publisher	Okayama University Medical School
Start Page	221
End Page	229
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2025 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	40859438
Web of Science KeyUT	001566286400001

Association of emergency intensive care unit occupancy due to brain-dead organ donors with ambulance diversion

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Hongo, Takashi\| Nojima, Tsuyoshi\| Tsukahara, Kohei\| Hisamura, Masaki\| Nakao, Atsunori\| Yorifuji, Takashi\| Naito, Hiromichi\|
Keywords	Ambulance diversion Bed occupancy Brain death Emergency medical services Intensive care units Organ donation
Published Date	2025-04-12
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	12633
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40221631
DOI	10.1038/s41598-025-97198-7
Web of Science KeyUT	001466042000027
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-97198-7

Age-specific assessment of initial hemoglobin levels and shock index for predicting life-saving interventions in pediatric blunt liver and spleen injuries

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Obara, Takafumi\| Hongo, Takashi\| Iida, Atsuyoshi\| Tsukahara, Kohei\| Katsura, Morihiro\| Kondo, Yutaka\| Yasuda, Hideto\| Kushimoto, Shigeki\| Yorifuji, Takashi\| Naito, Hiromichi\| Nakao, Atsunori\| SHIPPs Study Group\|
Keywords	Abdominal injuries Blood transfusions Hemoglobin Hemostasis Shock index
Published Date	2025-03-12
Publication Title	Scientific Reports
Volume	volume15
Issue	issue1
Publisher	Nature Portfolio
Start Page	8502
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2025
File Version	publisher
PubMed ID	40074821
DOI	10.1038/s41598-025-92673-7
Web of Science KeyUT	001443941100009
Related Url	isVersionOf https://doi.org/10.1038/s41598-025-92673-7

A nationwide longitudinal survey of infantile injury and its recurrence in Japan

FullText URL	fulltext.pdf
Author	Hiraoka, Tomohiro\| Obara, Takafumi\| Matsumoto, Naomi\| Tsukahara, Kohei\| Hongo, Takashi\| Nojima, Tsuyoshi\| Hisamura, Masaki\| Yumoto, Tetsuya\| Nakao, Atsunori\| Yorifuji, Takashi\| Naito, Hiromichi\|
Keywords	Retrospective cohort study Injury recurrence Injury prevention
Note	The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76403-z\|
Published Date	2024-10-21
Publication Title	Scientific Reports
Volume	volume14
Issue	issue1
Publisher	Nature Portfolio
Start Page	24716
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	39433855
DOI	10.1038/s41598-024-76403-z
Web of Science KeyUT	001339991400047
Related Url	isVersionOf https://doi.org/10.1038/s41598-024-76403-z

Evolution and Effects of Ad Hoc Multidisciplinary Team Meetings in the Emergency Intensive Care Unit: A Five-Year Analysis

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Hongo, Takashi\| Obara, Takafumi\| Ageta, Kohei\| Aokage, Toshiyuki\| Tsukahara, Kohei\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	clinical conference end-of-life care ICU rounds multidisciplinary team meetings
Published Date	2024-07-24
Publication Title	Journal of Clinical Medicine
Volume	volume13
Issue	issue15
Publisher	MDPI
Start Page	4324
ISSN	2077-0383
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39124591
DOI	10.3390/jcm13154324
Web of Science KeyUT	001287177900001
Related Url	isVersionOf https://doi.org/10.3390/jcm13154324

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients

FullText URL	fulltext.pdf
Author	Tsuge, Mitsuru\| Ichihara, Eiki\| Hasegawa, Kou\| Kudo, Kenichiro\| Tanimoto, Yasushi\| Nouso, Kazuhiro\| Oda, Naohiro\| Mitsumune, Sho\| Kimura, Goro\| Yamada, Haruto\| Takata, Ichiro\| Mitsuhashi, Toshiharu\| Taniguchi, Akihiko\| Tsukahara, Kohei\| Aokage, Toshiyuki\| Hagiya, Hideharu\| Toyooka, Shinichi\| Tsukahara, Hirokazu\| Maeda, Yoshinobu\|
Keywords	novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
Published Date	2024-07-31
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue15
Publisher	MDPI
Start Page	8370
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39125944
DOI	10.3390/ijms25158370
Web of Science KeyUT	001286890700001
Related Url	isVersionOf https://doi.org/10.3390/ijms25158370

Organ donation after extracorporeal cardiopulmonary resuscitation: a nationwide retrospective cohort study

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Tsukahara, Kohei\| Obara, Takafumi\| Hongo, Takashi\| Nojima, Tsuyoshi\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Brain death Cardiopulmonary resuscitation Extracorporeal membrane oxygenation Organ transplantation Out-of-hospital cardiac arrest Tissue and organ procurement
Note	The version of record of this article, first published in Critical Care, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13054-024-04949-5\|
Published Date	2024-05-13
Publication Title	Critical Care
Volume	volume28
Issue	issue1
Publisher	BMC
Start Page	160
ISSN	1364-8535
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024.
File Version	publisher
PubMed ID	38741176
DOI	10.1186/s13054-024-04949-5
Web of Science KeyUT	001221675100001
Related Url	isVersionOf https://doi.org/10.1186/s13054-024-04949-5

A randomized controlled trial of teprenone in terms of preventing worsening of COVID-19 infection

FullText URL	fulltext.pdf
Author	Ichihara, Eiki\| Hasegawa, Kou\| Kudo, Kenichiro\| Tanimoto, Yasushi\| Nouso, Kazuhiro\| Oda, Naohiro\| Mitsumune, Sho\| Yamada, Haruto\| Takata, Ichiro\| Hagiya, Hideharu\| Mitsuhashi, Toshiharu\| Taniguchi, Akihiko\| Toyooka, Shinichi\| Tsukahara, Kohei\| Aokage, Toshiyuki\| Tsukahara, Hirokazu\| Kiura, Katsuyuki\| Maeda, Yoshinobu\|
Published Date	2023-10-26
Publication Title	PLoS ONE
Volume	volume18
Issue	issue10
Publisher	Public Library of Science
Start Page	e0287501
ISSN	1932-6203
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 Ichihara et al.
File Version	publisher
PubMed ID	37883347
DOI	10.1371/journal.pone.0287501
Web of Science KeyUT	001094123400028
Related Url	isVersionOf https://doi.org/10.1371/journal.pone.0287501

Radiation in an emergency situation: attempting to respect the patient's beliefs as reported by a minor

FullText URL	fulltext.pdf
Author	Yumoto, Tetsuya\| Hongo, Takashi\| Koide, Yasuhiro\| Obara, Takafumi\| Tsukahara, Kohei\| Naito, Hiromichi\| Nakao, Atsunori\|
Keywords	Emergency service Informed consent Radiation Treatment refusal
Note	The version of record of this article, first published in BMC Medical Ethics, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12910-023-00962-5\|
Published Date	2023-10-04
Publication Title	BMC Medical Ethics
Volume	volume24
Issue	issue1
Publisher	BMC
Start Page	80
ISSN	1472-6939
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2023.
File Version	publisher
PubMed ID	37794408
DOI	10.1186/s12910-023-00962-5
Web of Science KeyUT	001080177500004
Related Url	isVersionOf https://doi.org/10.1186/s12910-023-00962-5

An Unusual Presentation of Chest Pain and Laryngeal Discomfort in a Pregnant Woman: A Case Report and Literature Review

JaLCDOI	10.18926/AMO/65755
FullText URL	77_4_429.pdf
Author	Sasanami, Misa\| Iida, Atsuyoshi\| Iwamuro, Masaya\| Hirai, Ryousuke\| Obara, Takashi\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Naito, Hiromichi\| Nakao, Atsunori\|
Abstract	Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
Keywords	chest pain dysphagia esophageal dissection hematemesis
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2023-08
Volume	volume77
Issue	issue4
Publisher	Okayama University Medical School
Start Page	429
End Page	431
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2023 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	37635144
Web of Science KeyUT	001163659800012

Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice

FullText URL	fulltext.pdf
Author	Ageta, Kohei\| Hirayama, Takahiro\| Aokage, Toshiyuki\| Seya, Mizuki\| Meng, Ying\| Nojima, Tsuyoshi\| Yamamoto, Hirotsugu\| Obara, Takafumi\| Nakao, Atsunori\| Yumoto, Tetsuya\| Tsukahara, Kohei\| Naito, Hiromichi\|
Published Date	2023-08
Publication Title	Surgery
Volume	volume174
Issue	issue2
Publisher	Elsevier
Start Page	343
End Page	349
ISSN	0039-6060
NCID	AA00853880
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Author(s).
File Version	publisher
PubMed ID	37210236
DOI	10.1016/j.surg.2023.04.029
Web of Science KeyUT	001051321100001
Related Url	isVersionOf https://doi.org/10.1016/j.surg.2023.04.029

Successfully treated case of severe hypothermia secondary to myxedema coma

FullText URL	fulltext.pdf
Author	Yamamoto, Hirotsugu\| Hongo, Takashi\| Nojima, Tsuyoshi\| Obara, Takafumi\| Kosaki, Yoshinori\| Ageta, Kohei\| Tsukahara, Kohei\| Yumoto, Tetsuya\| Nakao, Atsunori\| Naito, Hiromichi\|
Keywords	Cardiac arrest diagnosis hypothermia hypothyroidism myxedema coma
Published Date	2023-03-14
Publication Title	Acute Medicine and Surgery
Volume	volume10
Issue	issue1
Publisher	Wiley
Start Page	e828
ISSN	2052-8817
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 The Authors.
File Version	publisher
PubMed ID	36936740
DOI	10.1002/ams2.828
Web of Science KeyUT	000949262800001
Related Url	isVersionOf https://doi.org/10.1002/ams2.828

Organ Donation after Extracorporeal Cardiopulmonary Resuscitation and Brain Death

JaLCDOI	10.18926/AMO/64372
FullText URL	77_1_117.pdf
Author	Obara, Takafumi\| Yumoto, Tetsuya\| Aoshima, Kenji\| Tsukahara, Kohei\| Naito, Hiromichi\| Nakao, Atsunori\|
Abstract	A 38-year-old primipara Japanese woman suffered cardiac arrest due to a pulmonary thromboembolism 1 day after undergoing a cesarean section. Extracorporeal cardiopulmonary resuscitation was initiated and extracorporeal membrane oxygenation support was needed for 24 h. Despite intensive care, the patient was diagnosed with brain death on day 6. With the family’s consent, comprehensive end-of-life care including organ donation was discussed based on our hospital’s policy. The family decided to donate her organs. Specific training and education are required for emergency physicians to optimize the process of incorporating organ donation into end-of-life care while respecting the patient’s and family’s wishes.
Keywords	brain death end-of-life extracorporeal cardiopulmonary resuscitation organ donation potential organ donor
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2023-02
Volume	volume77
Issue	issue1
Publisher	Okayama University Medical School
Start Page	117
End Page	120
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2023 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	36849156
Web of Science KeyUT	000953005500003

Short or Irregular Sleep Duration in Early Childhood Increases Risk of Injury for Primary School-Age Children: A Nationwide Longitudinal Birth Cohort in Japan

FullText URL	fulltext.pdf
Author	Obara, Takafumi\| Naito, Hiromichi\| Tsukahara, Kohei\| Matsumoto, Naomi\| Yamamoto, Hirotsugu\| Yorifuji, Takashi\| Nakao, Atsunori\|
Keywords	sleep habits trauma problematic behavior longitudinal study
Published Date	2021-09-09
Publication Title	International Journal of Environmental Research
Volume	volume18
Issue	issue18
Publisher	MDPI
Start Page	9512
ISSN	1660-4601
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 by the authors.
File Version	publisher
PubMed ID	34574435
DOI	10.3390/ijerph18189512
Web of Science KeyUT	000699559600001
Related Url	isVersionOf https://doi.org/10.3390/ijerph18189512