| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Akira| Fujii, Nobuharu| Obika, Mikako| Yamashita, Taro| Otsuka, Fumio| |
| Keywords | localized AL amyloidosis ymphadenopathy PET-CT systemic AL amyloidosis |
| Published Date | 2020-10-01 |
| Publication Title | Internal Medicine |
| Volume | volume59 |
| Issue | issue19 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 2415 |
| End Page | 2418 |
| ISSN | 1349-7235 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 32611959 |
| DOI | 10.2169/internalmedicine.4651-20 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.4651-20 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishimura, Yoshito| Hagiya, Hideharu| Obika, Mikako| Otsuka, Fumio| |
| Keywords | septic pulmonary embolism blood culture procalcitonin |
| Published Date | 2020-11-27 |
| Publication Title | Pathogens |
| Volume | volume9 |
| Issue | issue12 |
| Publisher | MDPI |
| Start Page | 995 |
| ISSN | 2076-0817 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 33260940 |
| DOI | 10.3390/pathogens9120995 |
| Web of Science KeyUT | 000602562400001 |
| Related Url | isVersionOf https://doi.org/10.3390/pathogens9120995 |
| JaLCDOI | 10.18926/AMO/60797 |
|---|---|
| FullText URL | 74_5_381.pdf |
| Author | Yamamoto, Koichiro| Hanayama, Yoshihisa| Hasegawa, Kou| Tokumasu, Kazuki| Miyoshi, Tomoko| Hagiya, Hideharu| Ogawa, Hiroko| Obika, Mikako| Itoshima, Koichi| Otsuka, Fumio| |
| Abstract | To clarify the relevance of prolactin (PRL) to clinical parameters in patients who visited our general medicine department, medical records of 353 patients in whom serum PRL levels were measured during the period from 2016 to 2018 were retrospectively reviewed. Data for 140 patients (M/F: 42/98) were analyzed after excluding patients lacking detailed records and patients taking dopaminergic agents. Median serum PRL levels were significantly lower in males than females: 6.5 ng/ml (IQR: 4.2-10.3) versus 8.1 ng/ml (5.9-12.9), respectively. Pain and general fatigue were the major symptoms at the first visit, and past histories of hypertension and dyslipidemia were frequent. Male patients with relatively high PRL levels (≥ 10 ng/ml) had significantly lower levels of serum albumin and significantly higher levels of serum LDH than those with low PRL (< 10 ng/ml). There were significant correlations of male PRL level with the erythrocyte sedimentation rate (R=0.62), serum LDH level (R=0.39) and serum albumin level (R=−0.52), while the level of serum CRP (R=0.33) showed an insignificant but weak positive correlation with PRL level. Collectively, these results show that PRL levels had gender-specific relevance to various clinical factors, with PRL levels in males being significantly related to inflammatory status. |
| Keywords | hormones hyperprolactinemia inflammation pituitary prolactin |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-10 |
| Volume | volume74 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 381 |
| End Page | 389 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33106693 |
| Web of Science KeyUT | 000581970100002 |
| NAID | 120006892923 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishimura, Yoshito| Hagiya, Hideharu| Kawano, Kaoru| Yokota, Yuya| Oka, Kosuke| Iio, Koji| Hasegawa, Kou| Obika, Mikako| Haruma, Tomoko| Ono, Sawako| Masuyama, Hisashi| Otsuka, Fumio| |
| Keywords | Non-typable Haemophilus influenzae Bacteremia beta-Lactamase-nonproducing ampicillin-resistance Adenomyosis Case report |
| Published Date | 2020-07-16 |
| Publication Title | BMC Infectious Diseases |
| Volume | volume20 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 521 |
| ISSN | 1471-2334 |
| NCID | AA1203502X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2020 |
| File Version | publisher |
| PubMed ID | 32678023 |
| DOI | 10.1186/s12879-020-05193-2 |
| Web of Science KeyUT | 000552431500010 |
| Related Url | isVersionOf https://doi.org/10.1186/s12879-020-05193-2 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yamamoto, Akira| Nishimura, Yoshito| Obika, Mikako| Morizane, Yuki| Otsuka, Fumio| |
| Keywords | anemia anemic retinopathy rectal cancer retinal detachment |
| Published Date | 2020-04-13 |
| Publication Title | Clinical Case Reports |
| Volume | volume8 |
| Issue | issue7 |
| Publisher | Wiley |
| Start Page | 1304 |
| End Page | 1305 |
| ISSN | 2050-0904 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 The Authors. |
| File Version | publisher |
| DOI | 10.1002/ccr3.2833 |
| NAID | 120006862787 |
| Web of Science KeyUT | 000525973300001 |
| Related Url | isVersionOf https://doi.org/10.1002/ccr3.2833 |
| JaLCDOI | 10.18926/AMO/57950 |
|---|---|
| FullText URL | 74_1_33.pdf |
| Author | Honda, Hiroyuki| Hanayama, Yoshihisa| Obika, Mikako| Hasegawa, Kou| Hamahara, Jun| Kishida, Masayuki| Hagiya, Hideharu| Ogawa, Hiroko| Kataoka, Hitomi| Otsuka, Fumio| |
| Abstract | A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients’ gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (≥ 36) showed higher (FSSG) dysmotility symptom scores versus the low-SDS (< 36) group, although the 2 groups’ characteristics and laboratory data were not significantly different. Positive correlations of postprandial plasma glucose (PPG) levels with FSSG scores (R=0.321, p<0.05), particularly with reflux scores (R=0.455, p<0.01) were revealed. PPG and HbA1c levels were not correlated with SDS scores. The patients’ SDS scores were significantly correlated with their FSSG scores (R=0.41, p<0.01), suggesting that depressive status is linked to GERD-related manifestations. Considering that the patients’ PPG levels were correlated with GERD-related symptoms, diabetic patients’ blood glucose levels are associated with depressive status. Collectively, key symptoms related to GERD and glucose level values would be helpful |
| Keywords | blood glucose type 2 diabetes mellitus gastroesophageal reflux depressive status postprandial plasma glucose |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-02 |
| Volume | volume74 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 33 |
| End Page | 40 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32099246 |
| Web of Science KeyUT | 000516606200005 |
| NAID | 120006795617 |
| JaLCDOI | 10.18926/AMO/57711 |
|---|---|
| FullText URL | 73_6_479.pdf |
| Author | Suganami, Yu| Oka, Kosuke| Hanayama, Yoshihisa| Honda, Hiroyuki| Hamahara, Jun| Obika, Mikako| Kariyama, Kazuya| Kishida, Masayuki| Otsuka, Fumio| |
| Abstract | To clarify the potential relevance of patients’ chief complaints at a general medicine department to their self-rating depression scale (SDS) and frequency scale for symptoms of gastroesophageal reflux disease (GERD) (FSSG) scores, we analyzed data of 478 patients who visited our general medicine department. The chief complaints (553 symptoms of 447 patients) were categorized into major symptom-based groups: respiratory (31%), circulatory (3%), gastrointestinal (GI) tract (26%), neurology (8%), orthopedic and skin (10%), and systemic (22%) symptoms. The SDS score tended to be higher in females and younger patients. The FSSG score did not differ by gender but was higher in younger patients. The patients receiving social welfare had higher SDS and FSSG scores. A close inter-relationship between the FSSG (including both degrees of reflux and dysmotility) and SDS was observed in all patients. Although the averages of the SDS and FSSG scores were not significantly different among the symptom-based categories, we observed significantly positive correlations between the FSSG and SDS in each category, suggesting that depressive status may be closely related to GERD-related symptoms regardless of the patients’ chief complaints. An initial checkup of patients’ psychological condition and/or GERD-like symptoms could help screen for latent disorders in outpatients with uncertain complaints. |
| Keywords | chief complaints frequency scale for the symptoms of gastroesophageal reflux disease (FSSG) self-rating depression scale (SDS) welfare |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-12 |
| Volume | volume73 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 479 |
| End Page | 486 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31871329 |
| Web of Science KeyUT | 000503431400002 |
| FullText URL | BMCMedEduc_19_1_87.pdf |
|---|---|
| Author | Yamamoto, Akira| Obika, Mikako| Mandai, Yasuhiro| Murakami, Taku| Miyoshi, Tomoko| Ino, Hideo| Kataoka, Hitomi| Otsuka, Fumio| |
| Keywords | Simulation-based learning Peer-assisted learning Lecture Postgraduate education Junior residents |
| Published Date | 2019-03-20 |
| Publication Title | BMC Medical Education |
| Volume | volume19 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 87 |
| ISSN | 1472-6920 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 30894162 |
| DOI | 10.1186/s12909-019-1509-y |
| Web of Science KeyUT | 000462328100001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12909-019-1509-y |
| JaLCDOI | 10.18926/AMO/57370 |
|---|---|
| FullText URL | 73_5_403.pdf |
| Author | Ando, Akemi| Mitsuhashi, Toshiharu| Honda, Mitsugi| Hanayama, Yoshihisa| Hasegawa, Kou| Obika, Mikako| Kataoka, Hitomi| Otsuka, Fumio| |
| Abstract | Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual’s bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients’ BMD values and changes in the patients’ physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients’ gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general-practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level. |
| Keywords | bone mineral density (BMD) body mass index (BMI) female gender hypercalcemia osteoporosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-10 |
| Volume | volume73 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 403 |
| End Page | 411 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31649366 |
| Web of Science KeyUT | 000491886600005 |
| JaLCDOI | 10.18926/AMO/52789 |
|---|---|
| FullText URL | 68_4_235.pdf |
| Author | Ono, Tetsuichiro| Shikata, Kenichi| Obika, Mikako| Miyatake, Nobuyuki| Kodera, Ryo| Hirota, Daisyo| Wada, Jun| Kataoka, Hitomi| Ogawa, Daisuke| Makino, Hirofumi| |
| Abstract | The aim of this study was to clarify the factors associated with the remission and/or regression of microalbuminuria in Japanese patients with type 2 diabetes mellitus. We retrospectively analyzed the data of 130 patients with type 2 diabetes mellitus with microalbuminuria for 2-6 years (3.39±1.31 years). Remission was defined as improving from microalbuminuria to normoalbuminuria using the albumin/creatinine ratio (ACR), and regression of microalbuminuria was defined as a decrease in ACR of 50% or more from baseline. Progression of microalbuminuria was defined as progressing from microalbuminuria to overt proteinuria during the follow-up period. Among 130 patients with type 2 diabetes mellitus with microalbuminuria, 57 and 13 patients were defined as having remission and regression, respectively, while 26 patients progressed to overt proteinuria. Sex (female), higher HDL cholesterol and lower HbA1c were determinant factors associated with remission/regression of microalbuminuria by logistic regression analysis. Lower systolic blood pressure (SBP) was also correlated with remission/regression, but not at a significant level. These results suggest that proper control of blood glucose, BP and lipid profiles may be associated with remission and/or regression of type 2 diabetes mellitus with microalbuminuria in clinical practice. |
| Keywords | microalbuminuria type 2 diabetes mellitus remission regression |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-08 |
| Volume | volume68 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 235 |
| End Page | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25145409 |
| Web of Science KeyUT | 000340687500005 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/52828 |
