Uehara, Takashi - OU Author List - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Epigenetic Regulation of CXC Chemokine Expression by Environmental Electrophiles Through DNA Methyltransferase Inhibition

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Author	Tsuchida, Tomoki\| Kubota, Sho\| Kamiuezono, Shizuki\| Takasugi, Nobumasa\| Ito, Akihiro\| Kumagai, Yoshito\| Uehara, Takashi\|
Keywords	DNA methylation DNA methyltransferase chemical modification chemokine cell proliferation toxicology exposome environmental electrophiles
Published Date	2024-10-29
Publication Title	International Journal of Molecular Sciences
Volume	volume25
Issue	issue21
Publisher	MDPI
Start Page	11592
ISSN	1661-6596
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 by the authors.
File Version	publisher
PubMed ID	39519144
DOI	10.3390/ijms252111592
Web of Science KeyUT	001351300600001
Related Url	isVersionOf https://doi.org/10.3390/ijms252111592

Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling

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Author	Morimoto, Atsushi\| Takasugi, Nobumasa\| Pan, Yuexuan\| Kubota, Sho\| Dohmae, Naoshi\| Abiko, Yumi\| Uchida, Koji\| Kumagai, Yoshito\| Uehara, Takashi\|
Keywords	phosphatidylinositol 3-kinase (PI 3-kinase) cell signaling chemical modification autophagy glucose uptake
Published Date	2024-03
Publication Title	Journal of Biological Chemistry
Volume	volume300
Issue	issue3
Publisher	Elsevier
Start Page	105679
ISSN	1083-351X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 THE AUTHORS.
File Version	publisher
PubMed ID	38272219
DOI	10.1016/j.jbc.2024.105679
Web of Science KeyUT	001345391900001
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Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice

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Author	Miki, Ryohei\| Nomura, Ryosuke\| Iijima, Yuta\| Kubota, Sho\| Takasugi, Nobumasa\| Iwawaki, Takao\| Fujimura, Masatake\| Uehara, Takashi\|
Keywords	Methylmercury Neuronal cell death Endoplasmic reticulum stress Unfolded protein response
Note	The version of record of this article, first published in Archives of Toxicology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00204-024-03902-3\|
Published Date	2024-10-27
Publication Title	Archives of Toxicology
Volume	volume99
Issue	issue2
Publisher	Springer Science and Business Media LLC
Start Page	563
End Page	574
ISSN	0340-5761
NCID	AA00548865
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2024
File Version	publisher
PubMed ID	39465421
DOI	10.1007/s00204-024-03902-3
Web of Science KeyUT	001343204000001
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Epigenetic Regulation of Carbonic Anhydrase 9 Expression by Nitric Oxide in Human Small Airway Epithelial Cells

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Author	Moriya, Yuto\| Kubota, Sho\| Iijima, Yuta\| Takasugi, Nobumasa\| Uehara, Takashi\|
Keywords	nitric oxide human small airway epithelial cell epigenetics DNA methylation carbonic anhydrase 9 hypoxia-inducible factor 1 alpha
Published Date	2024-06-05
Publication Title	Biological and Pharmaceutical Bulletin
Volume	volume47
Issue	issue6
Publisher	Pharmaceutical Society of Japan
Start Page	1119
End Page	1122
ISSN	0918-6158
NCID	AA10885497
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 Author(s)
File Version	publisher
PubMed ID	38839363
DOI	10.1248/bpb.b24-00241
Web of Science KeyUT	001241469600003
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Attenuation of protein arginine dimethylation via S-nitrosylation of protein arginine methyltransferase 1

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Author	Taniguchi, Rikako\| Moriya, Yuto\| Dohmae, Naoshi\| Suzuki, Takehiro\| Nakahara, Kengo\| Kubota, Sho\| Takasugi, Nobumasa\| Uehara, Takashi\|
Keywords	Nitric oxide S-Nitrosylation Protein arginine methyltransferase 1 (PRMT1) RNA metabolism Dead-box helicase 3X-linxed (DDX3)
Published Date	2024-03
Publication Title	Journal of Pharmacological Sciences
Volume	volume154
Issue	issue3
Publisher	Japanese Pharmacological Society
Start Page	209
End Page	217
ISSN	1347-8613
NCID	AA11806667
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Authors.
File Version	publisher
PubMed ID	38395522
DOI	10.1016/j.jphs.2023.12.012
Web of Science KeyUT	001180873100001
Related Url	isVersionOf https://doi.org/10.1016/j.jphs.2023.12.012

Methylmercury-induced brain neuronal death in CHOP-knockout mice

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Author	Iijima, Yuta\| Miki, Ryohei\| Fujimura, Masatake\| Oyadomari, Seiichi\| Uehara, Takashi\|
Keywords	Methylmercury Neuronal cell death Apoptosis CHOP Knockout mouse
Published Date	2024
Publication Title	The Journal of Toxicological Sciences
Volume	volume49
Issue	issue2
Publisher	Japanese Society of Toxicology
Start Page	55
End Page	60
ISSN	0388-1350
NCID	AN00002808
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2024 The Japanese Society of Toxicology
File Version	publisher
PubMed ID	38296529
DOI	10.2131/jts.49.55
Web of Science KeyUT	001157348600004
Related Url	isVersionOf https://doi.org/10.2131/jts.49.55

Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis

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Author	Okuda, Kosaku\| Nakahara, Kengo\| Ito, Akihiro\| Iijima, Yuta\| Nomura, Ryosuke\| Kumar, Ashutosh\| Fujikawa, Kana\| Adachi, Kazuya\| Shimada, Yuki\| Fujio, Satoshi\| Yamamoto, Reina\| Takasugi, Nobumasa\| Onuma, Kunishige\| Osaki, Mitsuhiko\| Okada, Futoshi\| Ukegawa, Taichi\| Takeuchi, Yasuo\| Yasui, Norihisa\| Yamashita, Atsuko\| Marusawa, Hiroyuki\| Matsushita, Yosuke\| Katagiri, Toyomasa\| Shibata, Takahiro\| Uchida, Koji\| Niu, Sheng-Yong\| Lang, Nhi B.\| Nakamura, Tomohiro\| Zhang, Kam Y. J.\| Lipton, Stuart A.\| Uehara, Takashi\|
Note	The version of record of this article, first published in Nature Communications, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41467-023-36232-6\|
Published Date	2023-02-04
Publication Title	Nature Communications
Volume	volume14
Issue	issue1
Publisher	Nature Portfolio
Start Page	621
ISSN	2041-1723
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2023
File Version	publisher
PubMed ID	36739439
DOI	10.1038/s41467-023-36232-6
Web of Science KeyUT	001024149400011
Related Url	isVersionOf https://doi.org/10.1038/s41467-023-36232-6

The Pursuit of the "Inside" of the Amyloid Hypothesis-Is C99 a Promising Therapeutic Target for Alzheimer's Disease?

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Author	Takasugi, Nobumasa\| Komai, Masato\| Kaneshiro, Nanaka\| Ikeda, Atsuya\| Kamikubo, Yuji\| Uehara, Takashi\|
Keywords	Alzheimer's disease amyloid-beta amyloid beta precursor protein BACE1 C99 endolysosome autolysosome vesicular trafficking
Published Date	2023-01-31
Publication Title	Cells
Volume	volume12
Issue	issue3
Publisher	MDPI
Start Page	454
ISSN	2073-4409
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2023 by the authors.
File Version	publisher
PubMed ID	36766796
DOI	10.3390/cells12030454
Web of Science KeyUT	000931442200001
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Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain

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Author	Nomura, Ryosuke\| Takasugi, Nobumasa\| Hiraoka, Hideki\| Iijima, Yuta\| Iwawaki, Takao\| Kumagai, Yoshito\| Fujimura, Masatake\| Uehara, Takashi\|
Keywords	methylmercury neuronal cell death endoplasmic reticulum stress unfolded protein response ERAI system
Published Date	2022-12-06
Publication Title	International Journal Of Molecular Sciences
Volume	volume23
Issue	issue23
Publisher	MDPI
Start Page	15412
ISSN	1422-0067
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 by the authors.
File Version	publisher
PubMed ID	36499738
DOI	10.3390/ijms232315412
Web of Science KeyUT	000897330300001
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Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease

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Author	Kaneshiro, Nanaka\| Komai, Masato\| Imaoka, Ryosuke\| Ikeda, Atsuya\| Kamikubo, Yuji\| Saito, Takashi\| Saido, Takaomi C.\| Tomita, Taisuke\| Hashimoto, Tadafumi\| Iwatsubo, Takeshi\| Sakurai, Takashi\| Uehara, Takashi\| Takasugi, Nobumasa\|
Published Date	2022-03-18
Publication Title	Iscience
Volume	volume25
Issue	issue3
Publisher	Cell Press
Start Page	103869
ISSN	2589-0042
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2022 The Author(s).
File Version	publisher
PubMed ID	35243232
DOI	10.1016/j.isci.2022.103869
Web of Science KeyUT	000773445100002
Related Url	isVersionOf https://doi.org/10.1016/j.isci.2022.103869

Covalent N-arylation by the pollutant 1,2-naphthoquinone activates the EGF receptor

FullText URL	fulltext20210530_3.pdf
Author	Nakahara, Kengo\| Hamada, Kyohei\| Tsuchida, Tomoki\| Takasugi, Nobumasa\| Abiko, Yumi\| Shien, Kazuhiko\| Toyooka, Shinichi\| Kumagai, Yoshito\| Uehara, Takashi\|
Keywords	epidermal growth factor receptor cell signaling chemical modification signal transduction apoptosis
Published Date	2021-12-31
Publication Title	Journal of Biological Chemistry
Volume	volume296
Publisher	Elsevier
Start Page	100524
ISSN	00219258
NCID	AA00251083
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2021 The Authors.
File Version	publisher
PubMed ID	33705793
DOI	10.1016/j.jbc.2021.100524
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Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain

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Author	Hiraoka, Hideki\| Nomura, Ryosuke\| Takasugi, Nobumasa\| Akai, Ryoko\| Iwawaki, Takao\| Kumagai, Yoshito\| Fujimura, Masatake\| Uehara, Takashi\|
Keywords	Methylmercury Neuronal cell death ER stress UPR ERAI gene
Note	This is a post-peer-review, pre-copyedit version of an article published in Archives of Toxicology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00204-021-02982-9.\|
Published Date	2021-01-16
Publication Title	Archives of Toxicology
Volume	volume95
Issue	issue4
Publisher	Springer
Start Page	1241
End Page	1250
ISSN	0340-5761
NCID	AA00548865
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33454823
DOI	10.1007/s00204-021-02982-9
Web of Science KeyUT	000608083700002
Related Url	isVersionOf https://doi.org/10.1007/s00204-021-02982-9

Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress

Author	Ryosuke, Nakato\| Yu, Ohkubo\| Akari, Konishi\| Mari, Shibata\| Yuki, Kaneko\| Takao, Iwawaki\| Tomohiro, Nakamura\| Stuart A., Lipton\| Takashi, Uehara\|
Published Date	2015
Publication Title	Scientific Reports
Volume	volume5
Content Type	Journal Article