Okayama University Medical School Acta Medica Okayama 0386-300X 61 6 2007 Vaginoplasty with an M-Shaped Perineo- Scrotal Flap in a Male-to-female Transsexual 355 360 EN Yuzaburo Namba Narushi Sugiyama Shuji Yamashita Kenjiro Hasegawa Yoshihiro Kimata Kazushi Ishii Yasutomo Nasu Original Article 10.18926/AMO/32875 <p>To date, many techniques have been reported for vaginoplasty in male-to-female trans-sexual (MTFTS) patients, such as the use of a rectum transfer, a penile-scrotal flap and a reversed penile flap. However, none of these procedures is without its disadvantages. We developed a newly kind of flap for vaginoplasty, the M-shaped perineo-scrotal flap (M-shaped flap), using skin from both sides of the scrotum, shorn of hair by preoperative laser treatment. We applied this new type of flap in 7 MTFTS patients between January 2006 and January 2007. None of the flaps developed necrosis, and the patients could engage in sexual activity within 3 months of the operation. The M-shaped flap has numerous advantages: it can be elevated safely while retaining good vascularity, it provides for the construction of a sufficient deep vagina without a skin graft, the size of the flap is not influenced entirely by the length of the penis, and it utilizes skin from both sides of the scrotal area, which is usually excised.</p> No potential conflict of interest relevant to this article was reported.

Okayama University Medical School Acta Medica Okayama 0386-300X 59 6 2005 Intracavernous injection of prostaglandin E1 is effective in patients with erectile dysfunction not responding to phosphodiseterase 5 inhibitors. 279 280 EN Atsushi Nagai Norihiro Kusumi Hiromu Tsuboi Kazushi Ishii Takashi Saika Yasutomo Nasu Hiromi Kumon Short Communication 10.18926/AMO/31956 <p>We report on 64 patients who did not achieve erections adequate for satisfactory sexual intercourse from among a total of 243 patients who were prescribed PDE5 inhibitors for erectile dysfunction (ED). Intracavernous injection (ICI) of PGE was performed in this non-responder group. An ICI of 20 or 40 mcg of PGE1 in 1 ml saline was performed and the responses evaluated. Forty-nine out of 64 (77 percent ) cases responded to 20 mcg of PGE1. Forty mcg of PGE was injected into the 15 non-responding cases, and 9 patients responded favorably. The overall effective rate was 58/64 (91 percent ). No major adverse effects were observed.</p> No potential conflict of interest relevant to this article was reported.

Acta Medica Okayama 2000 PRE-PENILE ARTERIES ARE DOMINANT IN THE REGULATION OF PENILE VASCULAR RESISTANCE IN THE RAT EN No potential conflict of interest relevant to this article was reported.