FullText URL fulltext20230911-01.pdf
Author Iwamuro, Masaya| Hamada, Kenta| Kawano, Seiji| Kawahara, Yoshiro| Otsuka, Motoyuki|
Keywords Benign diseases Diagnosis Esophagogastroduodenoscopy Non-neoplastic lesions Oral lesions Pharyngolaryngeal lesions
Published Date 2023-07-16
Publication Title World Journal of Gastrointestinal Endoscopy
Volume volume15
Issue issue7
Publisher Baishideng Publishing Group Inc.
Start Page 496
End Page 509
ISSN 1948-5190
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©The Author(s) 2023.
File Version publisher
PubMed ID 37547241
DOI 10.4253/wjge.v15.i7.496
Web of Science KeyUT 001046453000002
Related Url isVersionOf https://doi.org/10.4253/wjge.v15.i7.496
FullText URL fulltext.pdf
Author Kanzaki, Hiromitsu| Horii, Joichiro| Takenaka, Ryuta| Nakagawa, Hiroyuki| Matsueda, Kazuhiro| Tsuzuki, Takao| Kita, Masahide| Yamasaki, Yasushi| Tanaka, Takehiro| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Tomoda, Jun| Okada, Hiroyuki|
Published Date 2022-06-10
Publication Title Endoscopy International Open
Volume volume10
Issue issue06
Publisher Georg Thieme Verlag KG
Start Page E712
End Page E718
ISSN 2364-3722
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022. The Author(s).
File Version publisher
PubMed ID 35859656
DOI 10.1055/a-1793-9439
Web of Science KeyUT 000826506700001
Related Url isVersionOf https://doi.org/10.1055/a-1793-9439
JaLCDOI 10.18926/AMO/65755
FullText URL 77_4_429.pdf
Author Sasanami, Misa| Iida, Atsuyoshi| Iwamuro, Masaya| Hirai, Ryousuke| Obara, Takashi| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Abstract Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
Keywords chest pain dysphagia esophageal dissection hematemesis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 429
End Page 431
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635144
Web of Science KeyUT 001163659800012
JaLCDOI 10.18926/AMO/65740
FullText URL 77_4_347.pdf
Author Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki|
Abstract The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry.
Keywords flow cytometry stem cell transplantation transplantation-associated microangiopathy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 347
End Page 357
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635134
Web of Science KeyUT 001163659800002
FullText URL fulltext.pdf
Author Hirai, Ryosuke| Kawano, Seiji| Inoo, Shoko| Kuraoka, Sakiko| Okanoue, Shotaro| Satomi, Takuya| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Iwamuro, Masaya| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords Fibrinolytic agents Endoscopic submucosal resection Postoperative hemorrhage Purinergic P2Y receptor antagonists
Published Date 2022-09-29
Publication Title Gut and Liver
Volume volume17
Issue issue3
Publisher The Editorial Office of Gut and Liver
Start Page 404
End Page 411
ISSN 1976-2283
NCID AA12329814
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Gut and Liver.
File Version publisher
PubMed ID 36172713
DOI 10.5009/gnl220196
Web of Science KeyUT 000869939200001
Related Url isVersionOf https://doi.org/10.5009/gnl220196
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Otsuka, Motoyuki|
Keywords autoimmune gastritis esophagogastroduodenoscopy genetic predisposition lymphocyte oxidative stress
Published Date 2023-06-21
Publication Title Current Issues in Molecular Biology
Volume volume45
Issue issue7
Publisher MDPI
Start Page 5263
End Page 5275
ISSN 1467-3037
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 37504250
DOI 10.3390/cimb45070334
Web of Science KeyUT 001035130200001
Related Url isVersionOf https://doi.org/10.3390/cimb45070334
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kagawa, Shunsuke| Inoo, Shoko| Otsuka, Motoyuki|
Keywords immune checkpoint inhibitor chemotherapy-induced diarrhea immune-related adverse event colitis colonoscopy collagenous colitis
Published Date 2023-05-25
Publication Title Cureus
Volume volume15
Issue issue5
Publisher Springer
Start Page e39466
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Iwamuro et al.
File Version publisher
PubMed ID 37378156
DOI 10.7759/cureus.39466
Web of Science KeyUT 001023091300016
Related Url isVersionOf https://doi.org/10.7759/cureus.39466
JaLCDOI 10.18926/AMO/65488
FullText URL 77_3_235.pdf
Author Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki|
Abstract Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users.
Keywords anamorelin body weight cancer cachexia endocrine system
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-06
Volume volume77
Issue issue3
Publisher Okayama University Medical School
Start Page 235
End Page 241
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37357624
Web of Science KeyUT 001026279600001
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords Diagnosis Diffuse large B-cell lymphoma Duodenal neoplasms Esoph-agogastroduodenoscopy Follicular lymphoma Gastrointestinal lymphoma
Published Date 2023-03-28
Publication Title World Journal of Gastroenterology
Volume volume29
Issue issue12
Publisher Baishideng Publishing Group
Start Page 1852
End Page 1862
ISSN 1007-9327
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37032723
DOI 10.3748/wjg.v29.i12.1852
Web of Science KeyUT 000982154800007
Related Url isVersionOf https://doi.org/10.3748/wjg.v29.i12.1852
FullText URL fulltext20230530-03.pdf
Author Iwamuro, Masaya| Kusumoto, Chiaki| Nakagawa, Masahiro| Matsueda, Kazuhiro| Kobayashi, Sayo| Yoshioka, Masao| Inaba, Tomoki| Toyokawa, Tatsuya| Sakaguchi, Chihiro| Tanaka, Shouichi| Tanaka, Takehiro| Okada, Hiroyuki|
Keywords Gastric adenocarcinoma of the fundic gland type (GA-FG) gastric neoplasms oxyntic gland adenoma submucosal invasion
Published Date 2023-03-16
Publication Title Journal of Gastrointestinal Oncology
Volume volume14
Issue issue2
Publisher AME Publishing Company
Start Page 554
End Page 562
ISSN 2078-6891
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Journal of Gastrointestinal Oncology.
File Version publisher
PubMed ID 37201070
DOI 10.21037/jgo-22-870
Web of Science KeyUT 000992116200001
Related Url isVersionOf https://dx.doi.org/10.21037/jgo-22-870
Title Alternative A case of duodenal diverticulitis in a patient receiving tocilizumab for rheumatoid arthritis
Author Iwamuro, Masaya| Baba, Yuki| Kawahara, Yoshiro| Okada, Hiroyuki|
Abstract  A Japanese woman was diagnosed with rheumatoid arthritis at the age of 41. At the age of 56, her rheumatoid arthritis worsened and a subcutaneous injection of tocilizumab and oral prednisolone was administered, which led to an improvement of arthritis. At the age of 57, right lower abdominal pain and vomiting suddenly appeared. Abdominal computed tomography showed a parapapillary diverticulum in the descending duodenum. The diverticulum was filled with residue, and an inflammation of the surrounding adipose tissue was observed; no free air was found. The patient was diagnosed with duodenal diverticulitis and treated with antibiotics, which resulted in an uneventful recovery. The maximum value of CRP was 1.88㎎/dL on the third day of hospitalization. Esophagogastroduodenoscopy performed on the 8th day of hospitalization revealed a parapapillary diverticulum with adhesion of pus and redness of the mucosa at the opening of the diverticulum, consistent with diverticulitis. This case highlights that diverticulitis in infrequent areas such as the duodenum may occur in patients who are treated with tocilizumab. In addition, inflammation of diverticulitis may be underestimated because abnormal laboratory values such as those induced by inflammatory reactions are less likely to occur during tocilizumab treatment.
Keywords トシリズマブ(tocilizumab) 十二指腸憩室(duodenal diverticulum) 憩室炎(diverticulitis)
Publication Title Journal of Okayama Medical Association
Published Date 2022-12-01
Volume volume134
Issue issue3
Start Page 166
End Page 170
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.134.166
language Japanese
Copyright Holders Copyright (c) 2022 岡山医学会
File Version publisher
DOI 10.4044/joma.134.166
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Okada, Horoyuki|
Keywords carcinogenesis lymphocytes helicobacter pylori gastric adenocarcinoma flow cytometry
Published Date 2022-11-20
Publication Title Cureus Journal Of Medical Science
Volume volume14
Issue issue11
Publisher Cureus Inc.
Start Page e31713
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36569708
DOI 10.7759/cureus.31713
Web of Science KeyUT 000918257500029
Related Url isVersionOf https://doi.org/10.7759/cureus.31713
JaLCDOI 10.18926/AMO/64365
FullText URL 77_1_75.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Abstract Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis.
Keywords autoimmune gastritis esophagogastroduodenoscopy scattered lesions small white protrusions mucosal lesions
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 75
End Page 80
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849149
Web of Science KeyUT 000952973200001
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kono, Yoshiyasu| Kawano, Seiji| Okada, Horoyuki|
Keywords nivolumab ipilimumab immune -related adverse events immune checkpoint inhibitor esophagogastroduodenoscopy
Published Date 2022-12-19
Publication Title CUREUS JOURNAL OF MEDICAL SCIENCE
Volume volume14
Issue issue12
Publisher Cureus
Start Page e32710
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Iwamuro et al.
File Version publisher
PubMed ID 36686096
DOI 10.7759/cureus.32710
Web of Science KeyUT 000905471200003
Related Url isVersionOf https://doi.org/10.7759/cureus.32710
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Matsumura, Akifumi| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Published Date 2022-12-31
Publication Title Case Reports In Gastrointestinal Medicine
Volume volume2022
Publisher Hindawi Ltd
Start Page 4637707
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Masaya Iwamuro et al.
File Version publisher
PubMed ID 36624891
DOI 10.1155/2022/4637707
Web of Science KeyUT 000910999400001
Related Url isVersionOf https://doi.org/10.1155/2022/4637707
FullText URL fulltext.pdf
Author Kobashi, Mayu| Iwamuro, Masaya| Kuraoka, Sakiko| Inoo, Shoko| Okanoue, Shotaro| Satomi, Takuya| Hamada, Kenta| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords familial adenomatous polyposis gastric adenoma gastric cancer phenotypic variations
Published Date 2022-10-14
Publication Title Medicine
Volume volume101
Issue issue41
Publisher Lippincott Williams & Wilkins
Start Page e30997
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36254079
DOI 10.1097/MD.0000000000030997
Web of Science KeyUT 000868085500032
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030997
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Abe, Makoto| Sakae, Hiroyuki| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Tanaka, Takehiro| Kawano, Seiji| Otsuka, Fumio| Kawahara, Yoshiro| Yanai, Hiroyuki| Okada, Hiroyuki|
Keywords eradication flow cytometry Helicobacter pylori T lymphocytes
Published Date 2022-08-26
Publication Title Medicine
Volume volume101
Issue issue34
Publisher Lippincott Williams & Wilkins
Start Page e30241
ISSN 0025-7974
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 the Author(s).
File Version publisher
PubMed ID 36042652
DOI 10.1097/MD.0000000000030241
Web of Science KeyUT 000847532100050
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000030241
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Murayama, Somay Yamagata| Nakamura, Masahiko| Hamada, Kenta| Tanaka, Takehiro| Okada, Hiroyuki|
Published Date 2022-07-20
Publication Title Case Reports In Gastrointestinal Medicine
Volume volume2022
Publisher Hindawi Ltd
Start Page 4254605
ISSN 2090-6528
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Masaya Iwamuro et al.
File Version publisher
PubMed ID 35911659
DOI 10.1155/2022/4254605
Web of Science KeyUT 000853251100001
Related Url isVersionOf https://doi.org/10.1155/2022/4254605
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Tanaka, Takehiro| Kuraoka, Sakiko| Hamada, Kenta| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords esophagogastroduodenoscopy gastric erosion gastric ulcer zinc acetate dihydrate
Published Date 2022-07-01
Publication Title Internal Medicine
Volume volume61
Issue issue13
Publisher The Japanese Society of Internal Medicine
Start Page 1931
End Page 1938
ISSN 0918-2918
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 35781269
DOI 10.2169/internalmedicine.8625-21
Web of Science KeyUT 000823060200001
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.8625-21
FullText URL fulltext.pdf
Author Kametaka, Daisuke| Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Otsuka, Fumio| Kawahara, Yoshiro| Okada, Hiroyuki|
Keywords flow cytometry autoimmune gastritis atrophic gastritis Helicobacter pylori
Published Date 2022-05-25
Publication Title Current Issues In Molecular Biology
Volume volume44
Issue issue6
Publisher MDPI
Start Page 2443
End Page 2452
ISSN 1467-3037
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 35735608
DOI 10.3390/cimb44060167
Web of Science KeyUT 000816477400001
Related Url isVersionOf https://doi.org/10.3390/cimb44060167