岡山医学会Acta Medica Okayama0030-155812412012医療法人仁徳会 森下病院9191ENNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012湯原温泉病院8990ENNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012岡山県健康づくり財団附属病院8788ENNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012手足口病の合併症8385ENNobukoYamashitaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012薬物相互作用（23―抗精神病薬の薬物相互作用）7981ENKoheiKitagawaHisashiMatsunagaToshiakiSendoNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012市中肺炎の診療ガイドライン7577ENYasushiTanimotoNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012慢性心不全治療ガイドライン7173ENKazufumiNakamuraHiroshiItoNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012骨形成不全症の治療6770ENHiroyukiTanakaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012S-1/CDDP術前化学療法により組織学的CRが得られた幽門狭窄合併進行胃癌の１例6366ENMasahikoNishizakiYasuhiroFujiwaraYasuhiroChoudaTakashiKanazawaMotokiNinomiyaToshiyoshiFujiwaraA 59-year-old man with epigastric discomfort and anorexia was referred to our hospital. Endoscopy revealed a type 3 advanced gastric cancer with pyloric stenosis diagnosed as a poorly differentiated adenocarcinoma in the biopsy specimens. A gastrojejunal bypass operation was performed because of direct invasion to the pancreas. The patient was treated by three courses of neoadjuvant chemotherapy with S-1/CDDP. Follow-up abdominal CT scan revealed that the primary tumor had become smaller, suggesting that a partial response had been achieved. Distal gastrectomy with D2 lymphadenectomy was performed. The histopathological examination showed no residual cancer cells in the primary lesion or dissected lymph nodes. Final chemotherapy efficacy was evaluated as Grade 3. The patient was treated with S-1 for one year after the gastrectomy and lymphadenectomy and has been followed up for 18 months without evidence of recurrence.No potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012医療人育成の現況と課題4145ENHitomi UKataokaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012膵炎を伴った胃異所性膵の1切除例5962ENSusumuShinouraTakahitoYagiHiroshiSadamoriHiroakiMatsudaYuzoUmedaRyuichiYoshidaDaisukeSatohMasashiUtsumiNaosukeYokomichiTakashiKuiseToshiyoshiFujiwaraWe experienced a case of gastric aberrant pancreas with acute pancreatitis. The patient was a 42-year-old man. He was referred to our hospital because of epigastric pain. A CT scan and endoscopic examination revealed a gastric submucosal tumor with inflammation. His serum amylase level was high at 222 IU/l. Endoscopic ultrasonography revealed a hypoechoic mass lesion, 3 cm in diameter, at the body of his stomach. Endoscopic ultrasoundscopy-guided fine needle aspiration was performed. Pathological examination showed pancreatic tissue. So, he underwent partial gastrectomy due to gastric aberrant pancreas with pancreatitis. There are very few cases of gastric aberrant pancreas with pancreatitis on record.No potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012膵リンパ上皮嚢胞の2例5357ENRyosukeHamanoMasaruInagakiYuujiKimuraKentaIsodaKojiKitadaManabuNishieNagahisaNomuraNaoyukiTokunagaKenjiTakahashiHideakiMiyasouYosukeTsunemitsuShinyaOhtsukaKazuyaMiyoshiKazuhideIwakawaMasahikoTakahashiHiromiIwagakiA 35-year-old man was found to have a cystic mass in the pancreatic body on a routine health examination ; high serum CA19-9 was also detected. The enucleated cyst was diagnosed as a lymphoepithelial cyst (LEC). A 74-year-old man found to have a cystic mass in the pancreatic head by computer tomography as well as high serum CA19-9 was suspected of a cystic neoplasm of the pancreas (IPMN), and pylorus-preserving pancreaticoduodenectomy (PPPD) was performed. Pathologically, the cyst was found to be LEC. It is often difficult to diagnose pancreatic cyst as LEC preoperatively. Care should be taken not to do over-surgery for benign disease LEC.No potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012当院における大腸癌同時性肝転移症例の臨床病理学的検討4751ENHideakiMiyasouKazuhideIwakawaMasaruInagakiYuujiKimuraManabuNishieRyousukeHamanoNaoyukiTokunagaYousukeTunemitsuShinyaOtsukaHiromiIwagakiThis study was aimed to clarify the prognostic factors in colorectal cancer patients with synchronous liver metastasis. Fifty-four patients were assessed to evaluate prognoses according to various clinico-pathological factors and therapeutic procedures. The patients' survival was significantly related to extrahepatic distant metastasis and therapeutic procedures. Regarding therapeutic procedures, the liver resection group showed significantly improved survival compared with the chemotherapy group, especially in liver metastasis Grade B. For colorectal liver metastases, it is clear that liver resection is the most effective treatment at present. Further improvement of patient prognoses is expected to be achieved by future research on combination chemotherapy.No potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012ER型救急医療について3539ENShingoIchibaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012テロメア生物学から心筋再生医療の実用化へ2734ENHidemasaOhNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012ニガウリ抽出物の血糖降下作用に関する文献的考察1526ENMitsumasaMankuraYasukoNodaAkitaneMoriDiabetes mellitus (DM) represents a global health and economical problem. Many patients with DM in Asia, South America, India and East Africa have traditionally used the water extract of unripe fruits of Momordica charantia (bitter melon) as some form of complementary and alternative medicine. Studies of laboratory animals have shown the beneficial blood-glucose lowering and anti-diabetic effects of this remedy. Some oral components that bring lower blood glucose level have been isolated : charantin (sterol glycosides), charantin (polypeptide) and cucurbine-type triterpenes. Part of their actions are related to AMP-activated kinase and repression of the oxidative stress that is increased in DM. Most clinical reports are not fully convincing due to the lack of randomized control studies. The present article reviews the pharmacological and clinical effects of bitter melon with special emphasis on the anti-diabetic effects, and some effects that would require caution in the context of human trials.No potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012Damus-Kaye-Stansel吻合913ENYasuhiroFujiiShunjiSanoSadahikoAraiShingoKasaharaAtsushiTateishiMasamiTakagakiYasufumiFujitaSusumuOzawaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012同種抗原による移植片対白血病効果減弱のメカニズム58ENShojiAsakuraDaigoHashimotoShuichiroTakashimaHarukoSugiyamaYoshinobuMaedaKoichiAkashiMitsuneTanimotoTakanoriTeshimaNo potential conflict of interest relevant to this article was reported.岡山医学会Acta Medica Okayama0030-155812412012ランビエ絞輪周囲のECMによるdiffusion barrier形成と跳躍伝導における役割14ENYokoBekkuYoshifumiNinomiyaToshitakaOohashiNo potential conflict of interest relevant to this article was reported.