start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=225 end-page=234 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=医療における個人情報保護法 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=太田吉夫 kn-aut-sei=太田 kn-aut-mei=吉夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部・歯学部附属病院 医療情報部 en-keyword=個人情報 kn-keyword=個人情報 en-keyword=個人情報保護 kn-keyword=個人情報保護 en-keyword=プライバシー kn-keyword=プライバシー en-keyword=医療情報 kn-keyword=医療情報 END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=219 end-page=224 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Characterization and usefulness of a monoclonal antibody against human herpesvirus-7 DNA polymerase processivity factor kn-title=ヒトヘルペスウイルス7型のDNA ポリメラーゼサブユニットに対する単クローン抗体の性状と有用性 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A monoclonal antibody (MAb), IK17, was developed and found useful for the analysis of human herpesvirus-7 (HHV7) genome replication. In Western blot analysis, the MAb IK17 specifically detected an HHV7 DNA polymerase subunit,U27 protein,expressed in both Escherichia coli (E.Coli)and HHV7-infected cells.Analysis by the same method of truncated U27 proteins expressed in E. Coli demonstrated that the MAb IK17 recognizes an epitope between amino acid 1 and 133 of the U27 protein.The indirect immunofluorescence (IF)method with MAb IK17 detected an unexpected reduction of U27 protein in the infected cells that were treated with a viral DNA polymerase inhibitor,phosphonoacetic acid (PAA),although no reduction of U27 mRNA was observed in the cells by Northern blot analysis. The data suggest the possible usefulness of the MAb IK17 for obtaining clues to characterize an unknown feature of the U27 protein. Immunoprecipitation experiments with the MAb IK17 enabled to detect at least four U27 protein-associated phosphorylated polypeptides in addition to the U27 protein itself.The result indicates the usefulness of the MAb IK17 for qualitative and quantitative analysis of the U27 proteinassociated viral and cellular factors. These analyses contribute to elucidation of the HHV7 genome replication system. en-copyright= kn-copyright= en-aut-name=NambaHikaru en-aut-sei=Namba en-aut-mei=Hikaru kn-aut-name=難波ひかる kn-aut-sei=難波 kn-aut-mei=ひかる aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病原ウイルス学 en-keyword=ヒトヘルペスウイルス7型 (Human Herpesvirus-7) kn-keyword=ヒトヘルペスウイルス7型 (Human Herpesvirus-7) en-keyword=DNA polymerase processivity factor kn-keyword=DNA polymerase processivity factor en-keyword=単クローン抗体 (monoclonal antibody) kn-keyword=単クローン抗体 (monoclonal antibody) END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=211 end-page=217 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=骨軟部腫瘍診断と治療における近年の進歩 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=尾ｱ敏文 kn-aut-sei=尾ｱ kn-aut-mei=敏文 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 整形外科学 en-keyword=骨軟部腫瘍 kn-keyword=骨軟部腫瘍 en-keyword=治療 kn-keyword=治療 en-keyword=生存率 kn-keyword=生存率 en-keyword=機能再建 kn-keyword=機能再建 END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=205 end-page=209 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Ubiquitin/Proteasome経路を介した核内受容体turnoverにおけるSuppressor for Gal-1の役割 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=増山寿 kn-aut-sei=増山 kn-aut-mei=寿 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部 産科婦人科学 en-keyword=suppressor for gal-1 kn-keyword=suppressor for gal-1 en-keyword=turnover kn-keyword=turnover en-keyword=proteasome kn-keyword=proteasome en-keyword=nuclear receptor kn-keyword=nuclear receptor en-keyword=endocrine disrupting chemicals kn-keyword=endocrine disrupting chemicals END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=199 end-page=204 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=ヒストンアセチル化制御による実験的関節炎の抑制 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西田圭一郎 kn-aut-sei=西田 kn-aut-mei=圭一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 人体構成学 en-keyword=関節リウマチ kn-keyword=関節リウマチ en-keyword=エピジェネティクス kn-keyword=エピジェネティクス en-keyword=ヒストン脱アセチル化酵素阻害剤 kn-keyword=ヒストン脱アセチル化酵素阻害剤 en-keyword=CDKインヒビター kn-keyword=CDKインヒビター en-keyword=抗II型コラーゲン抗体誘導関節炎 kn-keyword=抗II型コラーゲン抗体誘導関節炎 END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=193 end-page=198 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=シナプス小胞エンドサイトーシスの制御機構に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=吉田祐美 kn-aut-sei=吉田 kn-aut-mei=祐美 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 脳神経制御学 en-keyword=エンドサイトーシス kn-keyword=エンドサイトーシス en-keyword=ダイナミン kn-keyword=ダイナミン en-keyword=アンフィファイジン kn-keyword=アンフィファイジン END start-ver=1.4 cd-journal=joma no-vol=117 cd-vols= no-issue=3 article-no= start-page=187 end-page=191 dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060104 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=活性酸素によるRB タンパクの酸化を介した細胞周期停止 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=寳迫睦美 kn-aut-sei=寳迫 kn-aut-mei=睦美 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=荻野哲也 kn-aut-sei=荻野 kn-aut-mei=哲也 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岡田茂 kn-aut-sei=岡田 kn-aut-mei=茂 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病態探究医学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病態探究医学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 病態探究医学 en-keyword=細胞周期 kn-keyword=細胞周期 en-keyword=RB タンパク kn-keyword=RB タンパク en-keyword=活性酸素 kn-keyword=活性酸素 en-keyword=モノクロラミン kn-keyword=モノクロラミン en-keyword=酸化ストレス kn-keyword=酸化ストレス END