Methemoglobin formation by nitrite ion in the hemolysates of normal and acatalasemic mice

The formation of methemoglobin from hemoglobin in the hemolysates of normal and acatalasemic mice was studied by addition of nitrite ion in the range from 0.99-2.60 mM. Data indicated that induction period of methemoglobin formation in the acatalasemic hemolysate is shorter than that in the normal hemolysate and maximal velocity in the acatalasemic hemolysate is heigher than that in the normal hemolysate. The results indicated that velocity of methemoglobin formation in the acatalasemic hemolysate is faster than that in the normal hemolysate.