The effects of benzothiophene and dibenzothiophene on the mitochondrial membrane

The effects of benzothiophene and dibensothiophene on the mitochondrial membrane were studied and the following results were obtained. 1. The uncoupling actions of benzothiophene and dibenzothiophene on the energy transfer reaction of mitochondria were observed in the order of dibenzothiophene and benzothiophene. 2. The K(+) release was induced by benzothiophene and dibenzothiophene, and its ability of K(+) release was in the order of dibenzothiophene and benzothiophene. 3. The uncoupling actions of naphthalane and anthracene were similar to that of benzothiophene and dibenzothiophene respectively.