Influence of Bleomycin on Hematopoietic Organ Part Ⅰ Influence of Bleomycin on Leukopoietic Functions of Bone Marrow from Normal Rabbits

In order to observe the influence of Bleomycin on the bone marrow leukopoiesis, clinical Tissue culture of bone marrow from normal rabbits was conducted. Bleomycin solution at various concentrations were added directly to the culture media and observations were carried out on the outgrowth, cell density, wandering velosity of pseudoeosinophils, carbon particle phagocytosis. The experimental results demonstrate that the leukopoietic functions of bone marrow were not inhibited in the medium containning 0.0005mg/ml, 0.05mg/ml and 5mg/ml of Bleomycin.