Studies on Agricultural Organofluoride Poisoning Part Ⅲ. Influences of an Organofluoride on Electrocardiograms

The influences of an organofluoride (Nissol) poisoning on the heart were studied with respect to ECG of experimental rabbits and 5 intoxicated patients. 1. In the rabbits initially there appeared depression of ST segments and giant T waves, and terminally they succumbed to the sudden onset of ventricular flutter and fibrillation. 2. ECG from the patients were characterized by bradycardia, PQ prolongation, and U waves, but no arhythmia was seen. 3. These clinical ECG findings are compatible with vagotonia or hypopotassemia.