Analytical Studies on the Column Chromatographic Determination of DNA Base Composition with Ion Exchange Resins

1. Many type of methods has been designed for determination of nucleic acid base composition. In this paper the a curacy of the results obtained using ion exchgers were tested about calf thymus DNA. The column chromatographic methods yield satisfactory results. 2. In the course of the operation, nutralization of acidic solution of nucleic acid bases must be carried out carefully to avoid precipitation of purine bases.