The Influences of Salivary Gland Hormone on the Hematopoiesis of Bone Marrow Part 3. Influences of the Salivary Gland Hormone on the Bone-Marrow Tissue Culture of Patients with Hypoplastic Anemia and Banti's Disease

With the purpose to study the direct influences of the salivary gland hormone on the hematopoietic function, of bone marrow, especially on the leucocyte series of patients with hypoplastic anemia and Banti's disease by bone-marrow tissue culture (our simple method), the following results were obtained, 1. In the bone marrow tissue of the cases with hypolastic anemia type 1 (type of blood cell arrest in the bone marrow, according to the classification by Prof. Hiraki) by our simple method, the tissue growth and the wanderiug velocity of mature neutrophils were increased as compared with those of the control. On the other hand, no significant difference could be observed as compared with those of the control in type Ⅱ (type of maturation arrest) and type V (type of panmyelophtisis). 2. In the patients with Banti's disease, the leucocyte series of bone marrow was accelerated by addition of Parotin as compared with those of control, in cases with relatively normal count of nucleated myelogenous cells. On the other hand, in cases with lower count of nucleated myelogenous cells, no significant effect could be observed in the tissue culture by addition of Parotin.