Studies on Carbohydrate Metabolism in Bone-Marrow Tissue Culture of Rabbits Part 3. Carbohydrate Metabolism in the Bone Marrow of Rabbits with Experimental Anemias and Effects of Various Drugs on the Carbohydrate Metabolism in Bone Marrow of Normal Rabbits

In observations of carbohydrate metabolism in the bone marrow of rabbits with experimental anemias by tissue culture (Carrel's flask method) and in the studies of effects of various drugs on the carbohydrate metabolism in the bone marrow of normal rabbits by tissue culture (the same method) the following findings were obtained: 1) In the bone marrow of rabbits given benzol injection for a short period of time, the carbohydrate metabolism has been inhibited. Moreover, in the bone marrow of rabbits administered with benzol injection for a long time, or injected with phenylhydrazine, korallgol, or exposed to X-rays, the carbohydrate metabolism has been more markedly inhibited. 2) The carbohydrate metabolism has been accelerated in the bone marrow of rabbits depleted of blood. 3) In the bone marrow of rabbits injected with saponin no abnormality can be observed in the carbohydrate metabolism. 4) Vitamin B(12) and bone marrow extracts have been found to act directly upon bone marrow as to promote the carbohydrate metabolism.