I have succeeded to obtain results as follows, by taking examination on the nerve distribution within bone-marrows of human, caw's, and cat's femur. 1) In case of human, or cow's femur, the nerve entered into the bone-marrow, together with nutrient artery, forming a thick primary trunk nerve bundle; whence, it branches the secondary trunk nerve bundle, from which again nerve fibres are divided which directly distribute to arterial walls. Moreover, nerve plexus is formed here and there at the arterial walls immediately after its entry; esp., good development can be seen in cow's case. As for a cat's, a thick nerve bundle runs paralell to arteries, derivating from it certain nerve fibres distributed towards arterial walls. Also as to middle arteries, nerve distribution presents most minute, while in the small ones, indicated very poor. 2) In venous system, nerves are merely seen in partial small venous sinusoid, but in a cat's case, it is detected to certain extent. From the above, one may know that even in human, caw. and cat, contraction or enlargement of middle arteries play a most important role for the inhibition or mobilization of blood cells within bonemarrow. 3) The innervation in parenchyma proves very poor for all the three, finding neither nerve plexus nor any terminal reticulum. From all these, nerves are seemed not to have important significance for the formation of blood cells in bone-marrow.