EXPERIMENTAL STUDIES ON THE LIVER INJURY Report Ⅲ. On the injuries of liver and pancreas in massive bleeding from the gastroduodenal artery

The author has made bleeding from the gastroduodenal artcry on dogs as an experimental massive gastroduodenal hemorrhage, and studied the speciality of it on the function of liver and pancreas, comparing the bleeding from the femoral artery alld normal dogs. (1) In the bleeding from the gastroduodenal artery, liver injury occurred early and was more intensive than in the bleeding from the femoral artery, in 12 hours after the bleeding. Difference between them became markedly as the time elapsed. (2) No changes in the serum diastase between them were noticed. (3) In the vagostigmin test, the bleeding from the gastroduodenal artery showed stronger reaction than in the normal dogs. And in the insulin tolerance test, it showed also increased insulin sensibility, but there were no differellce presumptively between the bleeding from the gastroduodenal artery and the bleeding from the femoral artery. The speciality of the bleeding from the gastroduodenal artery was not observed on the pancreas injury.