Journal of Okayama Medical Association
Published by Okayama Medical Association

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On the Effect of X-irradiation upon the Urease Activity

Nakanishi, Y.
Kanda, M.
Mimura, K.
Yamamoto, M.
Murakami, T.
67_883.pdf 469 KB
Published Date
1955-04-30
Abstract
In order to investigate the influence of X-irradiation upon the urease, the authors performed several experiments and obtained the following conclusion: 1) The urease action are influenced by X-irradiation. 2) The activity of urease is strengthened in the case of irradiation with from 40r to 120r, and inhibited in the case of irradiation ranging from 140r to 200r or 400r. 3) The effect of X-irradiation upon urease action is caused by the irradiation of urease itself, and not of the substrate (urea). 4) When KCN is added to the urease urea mixture, the urease activity is activated in proportion to the concentration of KCN. In the case of an addition of KCN to the urease urea mixture, the effect of X-irradiation upon the urease activity is slight in case of strong concentration of KCN, but appears distinctly in case of weak concentration of KCN. 5) When CuSO(4) is added to the urease urea mixture, the urease activity is inhibited in proportion to the concentration of CuSO(4). In the case of addition of CuSO(4) to the urease urea mixture, the effect of X-irradiation upon the urease activity is seen slightly in case of strong concentration of CuSO(4), but distinctly in case of weak concentration of CuSO(4). 6) In the case of solar radiation, the urease activity is inhibited in proportion to the time of solar radiation, and the urease activity which is inhibited by solar radiation for 30 minutes, is reactivated by X-irradiation with 80r.
ISSN
0030-1558
NCID
AN00032489