| ID | 32047 |
| JaLCDOI | |
| FullText URL | |
| Author |
Watanabe, Akiharu
Higashi, Toshihiro
Nagashima, Hideo
|
| Abstract | A reproducible animal model of fulminant hepatic failure was developed by intraperitoneal administration of D-galactosamine hydrochloride to Sprague-Dawley rats. Biochemical and morphological hepatic injury and brain edema resembled human fulminant hepatic failure. This model would facilitate further studies of the pathogenesis of brain dysfunction and evaluation of treatment in fulminant hepatic failure. |
| Keywords | fulminant hepatic failure
brain edema
massive liver injury
hepatic encephalopathy
|
| Amo Type | Article
|
| Publication Title |
Acta Medica Okayama
|
| Published Date | 1979-12
|
| Volume | volume33
|
| Issue | issue6
|
| Publisher | Okayama University Medical School
|
| Start Page | 443
|
| End Page | 450
|
| ISSN | 0386-300X
|
| NCID | AA00508441
|
| Content Type |
Journal Article
|
| language |
English
|
| File Version | publisher
|
| Refereed |
True
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| PubMed ID | |
| NAID |