フルテキストURL K0005299_other1.pdf
著者 Itoh, Hideshi| Ichiba, Shingo| Ujike, Yoshihito| Kasahara, Shingo| Arai, Sadahiko| Sano, Shuji|
抄録  Extracorporeal membrane oxygenation (ECMO) has emerged as an effective mechanical support following cardiac surgery with respiratory and cardiac failure. However, there are no clear indications for ECMO use after pediatric cardiac surgery. We retrospectively reviewed medical records of 76 pediatric patients [mean age, 10.8 months (0-86); mean weight, 5.16 kg (1.16-16.5)] with congenital heart disease who received ECMO following cardiac surgery between January 1997 and October 2010. Forty-five patients were treated with an aggressive ECMO approach (aggressive ECMO group, April 2005-October 2010) and 31 with a delayed ECMO approach (delayed ECMO group, January 1997-March 2005). Demographics, diagnosis, operative variables, ECMO indication, and duration of survivors and non-survivors were compared. Thirty-four patients (75.5%) were successfully weaned from ECMO in the aggressive ECMO group and 26 (57.7%) were discharged. Conversely, eight patients (25.8%) were successfully weaned from ECMO in the delayed ECMO group and two (6.5%) were discharged. Forty-five patients with shunted single ventricle physiology (aggressive: 29 patients, delayed: 16 patients) received ECMO, but only 15 (33.3%) survived and were discharged. The survival rate of the aggressive ECMO group was significantly better when compared with the delayed ECMO group (p<0.01). Also, ECMO duration was significantly shorter among the aggressive ECMO group survivors (96.5 ± 62.9 h, p<0.01). Thus, the aggressive ECMO approach is a superior strategy compared to the delayed ECMO approach in pediatric cardiac patients. The aggressive ECMO approach improved our outcomes of neonatal and pediatric ECMO.
キーワード Extracorporeal membrane oxygenation congenital heart disease cardiac surgery pediatric hypoplastic left heart syndrome
備考 学位審査副論文
発行日 2012-05
出版物タイトル Perfusion
27巻
3号
出版者 SAGE
開始ページ 225
終了ページ 229
ISSN 0267-6591
NCID AA10674287
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 22249964
DOI 10.1177/0267659111434857
Web of Sience KeyUT 000303316500011
関連URL https://doi.org/10.1177/0267659111434857 http://ousar.lib.okayama-u.ac.jp/54282