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ID 60799
JaLCDOI
フルテキストURL
著者
Tsukioki, Takahiro Department of Breast and Endocrine Surgery, Okayama University Hospital
Shien, Tadahiko Department of Breast and Endocrine Surgery, Okayama University Hospital ORCID Kaken ID publons researchmap
Ohtani, Yusuke Department of Breast and Endocrine Surgery, Okayama University Hospital
Fujihara, Miwa Department of Breast and Endocrine Surgery, Okayama University Hospital
Suzuki, Yoko Department of Breast and Endocrine Surgery, Okayama University Hospital ORCID
Kajihara, Yukiko Department of Breast and Endocrine Surgery, Okayama University Hospital
Hatono, Minami Department of Breast and Endocrine Surgery, Okayama University Hospital
Kawada, Kengo Department of Breast and Endocrine Surgery, Okayama University Hospital
Kochi, Mariko Department of Breast and Endocrine Surgery, Okayama University Hospital
Iwamoto, Takayuki Department of Breast and Endocrine Surgery, Okayama University Hospital Kaken ID researchmap
Ikeda, Hirokuni Department of Breast and Endocrine Surgery, Okayama University Hospital
Taira, Naruto Department of Breast and Endocrine Surgery, Okayama University Hospital Kaken ID publons
Doihara, Hiroyoshi Department of Breast and Endocrine Surgery, Okayama University Hospital
抄録
Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC.
キーワード
differentiated thyroid carcinoma
juvenile
children
Amo Type
Original Article
発行日
2020-10
出版物タイトル
Acta Medica Okayama
74巻
5号
出版者
Okayama University Medical School
開始ページ
401
終了ページ
406
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID