著者 Furumatsu, Takayuki| Okazaki, Yuki| Hiranaka, Takaaki| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Zhang, Ximing| Ozaki, Toshifumi|
備考 This fulltext is available in Apr. 2021.|
発行日 2020-04-10
出版物タイトル Journal of Orthopaedic Science
26巻
2号
出版者 Elsevier
開始ページ 237
終了ページ 242
ISSN 09492658
NCID AA11052566
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 The Japanese Orthopaedic Association.
論文のバージョン author
PubMed ID 32284294
DOI 10.1016/j.jos.2020.03.012
関連URL isVersionOf https://doi.org/10.1016/j.jos.2020.03.012
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Miyazawa, Shinichi| Okazaki, Yoshiki| Okazaki, Yuki| Takihira, Shota| Kodama, Yuya| Kamatsuki, Yusuke| Masuda, Shin| Saito, Taichi| Ozaki, Toshifumi|
キーワード Medial meniscus posterior root tear Transtibial pullout repair Modified Mason-Allen suture Two simple stitches Clinical outcomes
備考 This fulltext is available in May 2021.|
発行日 2020-05-11
出版物タイトル The Knee
27巻
3号
出版者 Elsevier
開始ページ 701
終了ページ 708
ISSN 0968-0160
NCID AA10996272
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 Elsevier B.V.
論文のバージョン author
PubMed ID 32563426
DOI 10.1016/j.knee.2020.04.023
Web of Science KeyUT 000542165100013
関連URL isVersionOf https://doi.org/10.1016/j.knee.2020.04.023
フルテキストURL Knee_fulltext.pdf Knee_figure.pptx
著者 Okazaki, Yuki| Furumatsu, Takayuki| Okazaki, Yoshiki| Masuda, Shin| Hiranaka, Takaaki| Kodama, Yuya| Kamatsuki, Yusuke| Miyazawa, Shinichi| Tetsunaga, Tomonori| Ozaki, Toshifumi|
キーワード Magnetic resonance imaging Medial meniscus Meniscus extrusion Posterior root tear Three-dimensional assessment
発行日 2020-01-01
出版物タイトル The Knee
27巻
1号
出版者 Elsevier
開始ページ 132
終了ページ 139
ISSN 0968-0160
NCID AA10996272
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 31882388
DOI 10.1016/j.knee.2019.09.005
Web of Science KeyUT 000519666300017
関連URL isVersionOf https://doi.org/10.1016/j.knee.2019.09.005
フルテキストURL KSSTA_fulltext.pdf KSSTA_figure.pptx KSSTA_table.pptx
著者 Okazaki, Yoshiki| Furumatsu, Takayuki| Yamauchi, Takatsugu| Okazaki, Yuki| Kamatsuki, Yusuke| Hiranaka, Takaaki| Kajiki, Yuya| Zhang, Ximing| Ozaki, Toshifumi|
キーワード medial meniscus posterior root tear transtibial repair meniscal volume medial extrusion three-dimensional magnetic resonance imaging
備考 This fulltext is available in Apr. 2021.|
発行日 2020-04-06
出版物タイトル Knee Surgery, Sports Traumatology, Arthroscopy
28巻
出版者 Springer
開始ページ 3435
終了ページ 3442
ISSN 09422056
NCID AA10973641
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 32253480
DOI 10.1007/s00167-020-05953-2
Web of Science KeyUT 000525297800001
関連URL isVersionOf https://doi.org/10.1007/s00167-020-05953-2
JaLCDOI 10.18926/AMO/58274
フルテキストURL 74_2_151.pdf
著者 Yamamoto, Norio| Dan’ura, Tomoyuki| Noda, Tomoyuki| Ozaki, Toshifumi|
抄録 This is the second report of an atypical peri-implant femoral fracture occurring at the distal screw after intramedullary nail fixation of a pertrochanteric fracture. A 94-year-old Japanese female with a 5-year history of alendronate intake presented with prodromal pain in her right thigh after intramedullary nail fixation. Plain radiographs showed an incomplete noncomminuted transverse fracture at the distal screw, suggesting an atypical peri-implant femoral fracture. The pathogenesis of an atypical peri-implant femoral fracture could be a combined systemic bone metabolism disorder and repetitive overloading at the screw, similar to the pathogenesis of an atypical periprosthetic femoral fracture around stem implantation.
キーワード atypical femoral fracture insufficiency fracture bisphosphonate atypical peri-implant femoral fracture, atypical periprosthetic femoral fracture
Amo Type Case Report
発行日 2020-04
出版物タイトル Acta Medica Okayama
74巻
2号
出版者 Okayama University Medical School
開始ページ 151
終了ページ 157
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32341590
Web of Science KeyUT 000528278500009
NAID 120006839453
フルテキストURL fulltext.pdf
著者 Yamane, Kentaro| Misawa, Haruo| Takigawa, Tomoyuki| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro|
キーワード hepatocyte growth factor spinal cord injury neural regeneration
発行日 2019-12-02
出版物タイトル International Journal of Molecular Sciences
20巻
23号
出版者 MDPI
開始ページ 6078
ISSN 1422-0067
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 by the authors.
論文のバージョン publisher
PubMed ID 31810304
DOI 10.3390/ijms20236078
Web of Science KeyUT 000504428300260
関連URL isVersionOf https://doi.org/10.3390/ijms20236078
JaLCDOI 10.18926/AMO/57957
フルテキストURL 74_1_77.pdf
著者 Endo, Hirosuke| Akazawa, Hirofumi| Yashiro, Masato| Yamada, Kazuki| Sanki, Tomoaki| Tetsunaga, Tomonori| Nishida, Keiichiro| Furumatsu, Takayuki| Ozaki, Toshifumi|
抄録 Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up.
キーワード idiopathic chondrolysis hip joint medication bump arthroscopy
Amo Type Case Report
発行日 2020-02
出版物タイトル Acta Medica Okayama
74巻
1号
出版者 Okayama University Medical School
開始ページ 77
終了ページ 81
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32099253
Web of Science KeyUT 000516606200012
NAID 120006795624
JaLCDOI 10.18926/AMO/57947
フルテキストURL 74_1_7.pdf
著者 Sanki, Tomoaki| Endo, Hirosuke| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Ozaki, Toshifumi|
抄録 We investigated the relationship between the initial contact status and stress shielding in total hip arthroplasty (THA) using fit-and-fill type straight-stem implants. In addition we evaluated the clinical and radiographic outcomes. Subjects were 100 hips of 94 patients who underwent THA and were followed-up for ≥10 years. Contact areas with the femoral cortical bone were investigated according to the zonal distribution of Gruen using postoperative CT images. Depending on the number of contact areas, the patients were classified into high contact [HC], medium contact [MC], and low contact [LC] groups. Radiographic and clinical outcomes were evaluated. In the HC group (20 hips), severe stress shielding was observed in 12 hips, which was statistically significant (p=0.008). In the LC group (29 hips), mild stress shielding was observed in 27 hips which was statistically significant (p<0.001). No significant differences were observed among the 3 groups in clinical outcomes, Harris hip score (p=0.719) or Japanese Orthopedic Association (JOA) score (p=0.301). In insertion of cementless collared fit-and-fill type straight-stem implants, severe late stress shielding of the femoral bone may occur if high contact of the femoral component is achieved. However, the degree of stress shielding does not result in adverse clinical outcomes.
キーワード fit-and-fill stress shielding cementless straight stem total hip arthroplasty
Amo Type Original Article
発行日 2020-02
出版物タイトル Acta Medica Okayama
74巻
1号
出版者 Okayama University Medical School
開始ページ 7
終了ページ 15
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32099243
Web of Science KeyUT 000516606200002
NAID 120006795614
フルテキストURL CORR477_8_1892.pdf
著者 Kunisada, Toshiyuki| Fujiwara, Tomohiro| Hasei, Joe| Nakata, Eiji| Senda, Masuo| Ozaki, Toshifumi|
発行日 2019-08
出版物タイトル Clinical Orthopaedics and Related Research
477巻
8号
出版者 Lippincott, Williams & Wilkins
開始ページ 1892
終了ページ 1901
ISSN 0009-921X
NCID AA00607942
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 30985613
DOI 10.1097/CORR.0000000000000764
Web of Science KeyUT 000509664400024
関連URL isVersionOf https://doi.org/10.1097/CORR.0000000000000764
フルテキストURL fulltext.pdf
著者 Saito, Taichi| Noda, Tomoyuki| Kondo, Hiroya| Demiya, Koji| Nezu, Satoshi| Yokoo, Suguru| Matsuhashi, Minami| Uehara, Takenori| Shimamura, Yasunori| Kodama, Masayuki| Ozaki, Toshifumi|
抄録(別表記) Septic arthritis in distal interphalangeal (DIP) joints sometimes occurs in association with mucous cysts or after the surgical treatment of mallet fingers. Recently, several studies have demonstrated...
キーワード Hand Induced membrane Masquelet technique Septic arthritis The small joint
発行日 2020-02-29
出版物タイトル Trauma Case Reports
25巻
開始ページ 100268
ISSN 23526440
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 The Authors. Published by Elsevier Ltd.
論文のバージョン publisher
PubMed ID 1890833
DOI 10.1016/j.tcr.2019.100268
関連URL isVersionOf https://doi.org/10.1016/j.tcr.2019.100268
フルテキストURL AOTS20191023.pdf fig.pdf Table.pdf
著者 Yamamoto, Norio| Noda, Tomoyuki| Saito, Taichi| Uehara, Takenori| Shimamura, Yasunori| Ozaki, Toshifumi|
キーワード Acetabular fracture External iliac artery External iliac vein Ilioinguinal approach Occlusion Thrombosis
備考 This is a post-peer-review, pre-copyedit version of an article published in Archives of Orthopaedic and Trauma Surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00402-019-03288-3.|
発行日 2019-10-23
出版物タイトル Archives of Orthopaedic and Trauma Surgery
140巻
4号
出版者 Springer
開始ページ 481
終了ページ 485
ISSN 0936-8051
NCID AA10738765
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 31642955
DOI 10.1007/s00402-019-03288-3
Web of Science KeyUT 000492001100001
関連URL isVersionOf https://doi.org/10.1007/s00402-019-03288-3
フルテキストURL NCN7_3_146.pdf Fig.pdf
著者 Matsumoto, Namiko| Sato, Kota| Takahashi, Yoshiaki| Kawahara, Yuko| Yunoki, Taijun| Shang, Jingwei| Takemoto, Mami| Hishikawa, Nozomi| Ohta, Yasuyuki| Yamashita, Toru| Sakamoto, Maiko| Kondou, Eisei| Shibata, Rei| Yoshino, Tadashi| Ozaki, Toshifumi| Abe, Koji|
キーワード neurolymphomatosis neuro-oncology peripheral neuropathy peripheral nerve rheumatoid arthritis T-cell lymphoma
備考 This fulltext will be available in Feb 2020|
発行日 2019-02-19
出版物タイトル Neurology and Clinical Neuroscience
7巻
3号
出版者 Wiley
開始ページ 146
終了ページ 149
ISSN 2049-4173
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
DOI 10.1111/ncn3.12280
Web of Science KeyUT 000466785700011
関連URL isVersionOf https://doi.org/10.1111/ncn3.12280
JaLCDOI 10.18926/AMO/57717
フルテキストURL 73_6_523.pdf
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Masuda, Shin| Okazaki, Yuki| Takihira, Shota| Miyazawa, Shinichi| Nakata, Eiji| Ozaki, Toshifumi|
抄録 The case of an individual with a bilateral anterior cruciate ligament (ACL) tear combined with a medial meniscus (MM) posterior root tear is described. A 34-year-old Japanese man with bilateral ACL rupture that occurred > 10 years earlier was diagnosed with bilateral ACL tear combined with MM posterior root tear (MMPRT). We performed a transtibial pullout repair of the MMPRT with ACL reconstruction. The tibial tunnels for the MM posterior root repair and ACL reconstruction were created separately. Postoperatively, a good clinical outcome and meniscal healing were obtained. Our surgical technique may thus contribute to anatomical MM posterior root repair and ACL reconstruction.
キーワード bilateral anterior cruciate ligament tear medial meniscus posterior root tear pullout repair case report
Amo Type Case Report
発行日 2019-12
出版物タイトル Acta Medica Okayama
73巻
6号
出版者 Okayama University Medical School
開始ページ 523
終了ページ 528
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31871335
Web of Science KeyUT 000503431400008
JaLCDOI 10.18926/AMO/57714
フルテキストURL 73_6_503.pdf
著者 Kamatsuki, Yusuke| Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Hino, Tomohito| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Noda, Tomoyuki| Yamakawa, Yasuaki| Tetsunaga, Tomoko| Ozaki, Toshifumi|
抄録 Clinical studies have demonstrated that transtibial pullout repair led to favorable midterm outcomes in patients with medial meniscus posterior root tears (MMPRTs) although medial meniscal extrusion (MME) continued to be present. It has been unclear whether these residual postoperative MMEs existed after the pullout repair or had progressed at the very short-term evaluation after surgery. We sought to determine which characteristics of patients with MMPRTs influence the incidence of postoperative MME. The cases of 23 patients whose date of injury was known were analyzed. All patients underwent MMPRT pullout fixation. Preoperative and 3-month postoperative magnetic resonance imaging (MRI) examinations were performed. MME was retrospectively assessed on the mid-coronal plane of MRI scans. The preoperative and postoperative MME values were 4.2±1.2 mm and 4.3±1.5 mm, respectively (p=0.559). Pullout repair surgery was performed significantly earlier after the MMPRT-specific injury in patients whose postoperative MME improved compared to the patients whose MME did not improve (p<0.001). Our findings demonstrated that an early transtibial pullout repair of an MMPRT was more effective in reducing MME than a late repair. Surgeons should not miss the optimal timing for the pullout repair of an MMPRT, considering the period from the injury and the preoperative MME.
キーワード medial meniscus posterior root tear pullout repair medial meniscus extrusion magnetic resonance imaging
Amo Type Original Article
発行日 2019-12
出版物タイトル Acta Medica Okayama
73巻
6号
出版者 Okayama University Medical School
開始ページ 503
終了ページ 510
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31871332
Web of Science KeyUT 000503431400005
JaLCDOI 10.18926/AMO/57713
フルテキストURL 73_6_495.pdf
著者 Masuda, Shin| Furumatsu, Takayuki| Okazaki, Yoshiki| Kamatsuki, Yusuke| Okazaki, Yuki| Kodama, Yuya| Hiranaka, Takaaki| Nakata, Eiji| Ozaki, Toshifumi|
抄録 Medial meniscus posterior root tear causes rapid knee cartilage degradation by inducing posteromedial displacement of the medial meniscus. We evaluated medial meniscus posterior extrusion before and after pullout repair for medial meniscus posterior root tear using magnetic resonance images. Twenty-eight patients with symptomatic medial meniscus posterior root tear were included. The inclusion criteria were: acute (< 3 months) or chronic (≥3 months) medial meniscus posterior root tear after painful popping events. The exclusion criteria were: other meniscus and anterior cruciate ligament injuries. We measured medial meniscus posterior extrusion and medial meniscus anteroposterior interval at knee flexion angles of 10° and 90° preoperatively and at 3 months postoperatively. The posterior extrusion at 90° knee flexion decreased from 4.42±1.38 mm preoperatively to 3.09±1.06 mm (p<0.001) postoperatively, while at 10° knee flexion it was −4.17±1.63 mm preoperatively and −3.77±1.72mm postoperatively, showing no significant change. The anteroposterior interval at 10° knee flexion increased from 19.74±4.27 mm preoperatively to 22.15±5.10 mm postoperatively (p<0.001); at 90° knee flexion, it increased from 16.81±4.51 mm preoperatively to 19.20±4.30 mm postoperatively (p<0.001). Medial meniscus posterior extrusion and movement decreased after pullout repair. Pullout repair for medial meniscus posterior root tear improves medial meniscus posterior extrusion, especially at 90° knee flexion.
キーワード medial meniscus posterior root tear pullout repair extrusion open magnetic resonance imaging
Amo Type Original Article
発行日 2019-12
出版物タイトル Acta Medica Okayama
73巻
6号
出版者 Okayama University Medical School
開始ページ 495
終了ページ 501
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 31871331
Web of Science KeyUT 000503431400004
フルテキストURL KSSTA27_2_361.pdf Figs.pdf Table.pdf
著者 Okazaki, Yoshiki| Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Kamatsuki, Yusuke| Hino, Tomohito| Masuda, Shin| Ozaki, Toshifumi|
キーワード Anterior cruciate ligament reconstruction Flexed-knee position Medial meniscus Meniscal repair Open magnetic resonance imaging Posterior shift
発行日 2018-09-24
出版物タイトル Knee Surgery, Sports Traumatology, Arthroscopy
27巻
2号
出版者 Springer
開始ページ 361
終了ページ 368
ISSN 0942-2056
NCID AA10973641
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 30251100
DOI 10.1007/s00167-018-5157-2
Web of Science KeyUT 000460315200005
関連URL isVersionOf https://doi.org/10.1007/s00167-018-5157-2
フルテキストURL CTR_2019_1631298.pdf Fig.pdf
著者 Hino, Tomohito| Furumatsu, Takayuki| Miyazawa, Shinichi| Fujii, Masataka| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Ozaki, Toshifumi|
キーワード Medial meniscus posterior insertion histological analysis knee osteoarthritis medial meniscus posterior root tear transtibial pullout repair
発行日 2019-07-09
出版物タイトル Connective Tissue Research
61巻
6号
出版者 Taylor and Francis
開始ページ 546
終了ページ 553
ISSN 0300-8207
NCID AA00615033
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 31181971
DOI 10.1080/03008207.2019.1631298
Web of Science KeyUT 000478374800001
関連URL isVersionOf https://doi.org/10.1080/03008207.2019.1631298
フルテキストURL IntOrthop_43_5_1239.pdf Tables.pdf Fig.pdf
著者 Furumatsu, Takayuki| Miyazawa, Shinichi| Fujii, Masataka| Tanaka, Takaaki| Kodama, Yuya| Ozaki, Toshifumi|
キーワード Arthroscopic scoring Medial meniscus Meniscal healing Posterior root tear Transtibial pullout repair
発行日 2018-08-01
出版物タイトル International Orthopaedics
43巻
5号
出版者 Springer
開始ページ 1239
終了ページ 1245
ISSN 03412695
NCID AA0068148X
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 30069591
DOI 10.1007/s00264-018-4071-z
Web of Science KeyUT 000466730800024
関連URL isVersionOf https://doi.org/10.1007/s00264-018-4071-z
フルテキストURL JOS24_6_1058.pdf Figs.pdf Table.pdf
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Kamatsuki, Yusuke| Sugiu, Kazuhisa| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Takihira, Shota| Miyazawa, Shinichi| Nakata, Eiji| Ozaki, Toshifumi|
備考 This fulltext will be available in Nov 2020 |
発行日 2019-08-20
出版物タイトル Journal of Orthopaedic Science
24巻
6号
出版者 Elsevier
開始ページ 1058
終了ページ 1063
ISSN 09492658
NCID AA11052566
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
論文のバージョン author
PubMed ID 31444009
DOI 10.1016/j.jos.2019.08.001
Web of Science KeyUT 000496202800019
関連URL isVersionOf https://doi.org/10.1016/j.jos.2019.08.001
フルテキストURL Knee26_3_653.pdf tables.pdf Fig.pdf
著者 Furumatsu, Takayuki| Okazaki, Yuki| Kodama, Yuya| Okazaki, Yoshiki| Masuda, Shin| Kamatsuki, Yusuke| Takihira, Shota| Hiranaka, Takaaki| Yamawaki, Tadashi| Ozaki, Toshifumi|
キーワード Clinical outcome Medial meniscus Meniscal healing Posterior root tear Transtibial pullout repair
発行日 2019-06-30
出版物タイトル The Knee
26巻
3号
出版者 Elsevier
開始ページ 653
終了ページ 659
ISSN 09680160
NCID AA10996272
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 Elsevier B.V. All rights reserved.
論文のバージョン author
PubMed ID 30902517
DOI 10.1016/j.knee.2019.02.007
Web of Science KeyUT 000474504500017
関連URL isVersionOf https://doi.org/10.1016/j.knee.2019.02.007