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ID 48560
JaLCDOI
フルテキストURL
著者
Kataoka, Masaki Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Kunisada, Toshiyuki Medical Materials for Musculoskeletal Reconstruction, Okayama University Graduate School of Medicine Kaken ID researchmap
Tanaka, Masato Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Takeda, Ken Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Itani, Satoru Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Sugimoto, Yoshihisa Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Misawa, Haruo Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine
Senda, Masuo Department of Rehabilitation, Okayama University Hospital Kaken ID publons researchmap
Nakahara, Shinnosuke Department of Orthopaedic Surgery, Okayama Medical Center
Ozaki, Toshifumi Departments of Orthopaedic Surgery, Okayama University Graduate School of Medicine Kaken ID researchmap
抄録
There are a variety of treatment options for patients with spinal metastasis, and predicting prognosis is essential for selecting the proper treatment. The purpose of the present study was to identify the significant prognostic factors for the survival of patients with spinal metastasis. We retrospectively reviewed 143 patients with spinal metastasis. The median age was 61 years. Eleven factors reported previously were analyzed using the Cox proportional hazards model:gender, age, performance status, neurological deficits, pain, type of primary tumor, metastasis to major organs, previous chemotherapy, disease-free interval before spinal metastasis, multiple spinal metastases, and extra-spinal bone metastasis. The average survival of study patients after the first visit to our clinic was 22 months. Multivariate survival analysis demonstrated that type of primary tumor (hazard ratio [HR]=6.80, p<0.001), metastasis to major organs (HR=2.01, p=0.005), disease-free interval before spinal metastasis (HR=1.77, p=0.028), and extra-spinal bone metastasis (HR=1.75, p=0.017) were significant prognostic factors. Type of primary tumor was the most powerful prognostic factor. Other prognostic factors may differ among the types of primary tumor and may also be closely associated with primary disease activity. Further analysis of factors predicting prognosis should be conducted with respect to each type of primary tumor to help accurately predict prognosis.
キーワード
spine
metastasis
survival
prognostic factor
cancer
Amo Type
Original Article
発行日
2012-06
出版物タイトル
Acta Medica Okayama
66巻
3号
出版者
Okayama University Medical School
開始ページ
213
終了ページ
219
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT