JaLCDOI 10.18926/AMO/30979
フルテキストURL fulltext.pdf
著者 Imatoh, Takuya| Miyazaki, Motonobu| Momose, Yoshito| Uryu, Yoko| Tanihara, Shinichi| Une, Hiroshi| Doi, Hiroyuki|
抄録 <p>Leptin is a hormone which is predominantly secreted by adipose tissue. Recent studies have shown that leptin increases arterial blood pressure. Although data from available animal studies clearly indicate an association between leptin and hypertension, results of human studies have been less definitive. We conducted a case-control study to examine the association between serum leptin levels and hypertension in 111 hypertensive subjects and 222 male controls, using conditional logistic regression analyses. Mean serum leptin levels were found to be marginally higher in the case subjects than in the control subjects (3.3 ng/ml versus 3.0 ng/ml), however, conditional logistic regression analysis revealed that subjects in the highest quartile had a significantly increased risk of hypertension compared with those in the lowest quartile, even after adjusting for drinking status and diabetes mellitus (adjusted OR, 2.11;95% CI, 1.01-4.39). Our findings suggest that leptin plays an important role in the development of hypertension.</p>
キーワード epidemiological study hyperleptinemia hypertension leptin
Amo Type Original Article
発行日 2008-06
出版物タイトル Acta Medica Okayama
62巻
3号
出版者 Okayama University Medical School
開始ページ 169
終了ページ 174
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 18596833
Web of Science KeyUT 000257130300004
JaLCDOI 10.18926/AMO/30959
フルテキストURL fulltext.pdf
著者 Fukuoka, Etsuko| Hirokawa, Kumi| Kawakami, Norito| Tsuchiya, Masao| Haratani, Takashi| Kobayashi, Fumio| Araki, Shunichi| Doi, Hiroyuki|
抄録 <p>The purpose of the present study was to assess the association between job strain and smoking cessation among Japanese male employees. In 1997, a baseline questionnaire was given to 2,625 (2,113 males and 512 females) employees of an electronics firm in Gifu Prefecture, Japan. The self-administered questionnaire was a set of questions on smoking habits and consisted of items on socio-demographic variables and smoking habits, including the Japanese version of the Job Content Questionnaire (JCQ). The JCQ consists of scales of job control, job demand, supervisory support, coworker support, job insecurity, physical demands, and isometric load. A total of 733 male smokers were then followed for 2 years, with 446 completing a follow-up questionnaire in 1999 (follow-up rate, 61%). Logistic regression analyses were performed to examine associations between job strain and smoking cessation. Among the 446 participants, 38 had quit smoking. After adjusting for age ((odds ratio: OR) = 0.38, 95% (contidence interval: CI) = 0.15-0.94), men with a high level of physical demands at baseline showed a lower smoking cessation rate at follow-up than did those with a low level. However, when adjustments were made for age and other socio-demographic variables, the odds ratio of smoking cessation showed marginal significance (OR = 0.45, 95% CI = 0.16-1.29). There was no significant association between other job strain variables and smoking cessation at the 2-year follow-up. No significant association was found between job strain and change in the number of smoked cigarettes per day. The present study did not support the hypothesis that higher levels of job stressors are associated with a lower rate of smoking cessation among men.</p>
キーワード job strain smoking worksite support physical demands prospective cohort study
Amo Type Original Article
発行日 2008-04
出版物タイトル Acta Medica Okayama
62巻
2号
出版者 Okayama University Medical School
開始ページ 83
終了ページ 91
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 18464883
Web of Science KeyUT 000255297600004
JaLCDOI 10.18926/AMO/30938
フルテキストURL fulltext.pdf
著者 Babazono, Akira| Kitajima, Hiroyuki| Nishimaki, Shigeru| Nakamura, Tomohiko| Shiga, Seigo| Hayakawa, Masahiro| Tanaka, Tahei| Sato, Kazuo| Nakayama, Hideki| Ibara, Satoshi| Une, Hiroshi| Doi, Hiroyuki|
抄録 <p>We evaluated the infection risks in the neonatal intensive care unit (NICU) using data of NICU infection surveillance data. The subjects were 871 NICU babies, consisting of 465 boys and 406 girls, who were cared for between June 2002 and January 2003 in 7 medical institutions that employed NICU infection surveillance. Infections were defined according to the National Nosocomial Infection Surveillance (NNIS) System. Of the 58 babies with nosocomial infections, 15 had methicillin-resistant Staphylococcus aureus (MRSA) infection. Multiple logistic regression analysis demonstrated that the odds ratio for nosocomial infections was significantly related to gender, birth weight and the insertion of a central venous catheter (CVC). When the birth weight group of more than 1, 500g was regarded as the reference, the odds ratio was 2.35 in the birth weight group of 1,000-1,499g and 8.82 in the birth weight group of less than 1,000g. The odds ratio of the CVC () for nosocomial infection was 2.27. However, other devices including artificial ventilation, umbilical artery catheter, umbilical venous catheter, and urinary catheter were not significant risk factors. The incidence of MRSA infection rapidly increased from 0.3% in the birth weight group of more than 1,500g to 2.1% in the birth weight group of 1,000-1,499g, and to 11.1% in the birth weight group of less than 1,000g. When the birth weight group of more than 1,500g was regarded as the reference, multiple logistic regression analysis demonstrated that the odds ratio was 7.25 in the birth weight group of 1,000-1,499g and 42.88 in the birth weight group of less than 1,000g. These odds ratios were significantly higher than that in the reference group. However, the application of devices did not cause any significant differences in the odds ratio for MRSA infection.</p>
キーワード risk factors nosocomial infection neonatal intensive care unit JANIS
Amo Type Original Article
発行日 2008-08
出版物タイトル Acta Medica Okayama
62巻
4号
出版者 Okayama University Medical School
開始ページ 261
終了ページ 268
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 18766209
Web of Science KeyUT 000258680900006
タイトル(別表記) New antimalarial endoperoxides for drug-resistant Plasmodium falciparumn : The current situation
フルテキストURL 127_231.pdf
著者 金 惠淑| 片本 茜| 佐藤 聡| 綿矢 有佑| 土居 弘幸|
キーワード 薬剤耐性マラリア ACT療法(artemisinin-based combination therapy) 新薬開発 環状過酸化物 標的分子
出版物タイトル 岡山医学会雑誌
発行日 2015-12-01
127巻
3号
開始ページ 231
終了ページ 235
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.231
言語 Japanese
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.231
NAID 130005116817
フルテキストURL fulltext.pdf
著者 Liu, Yangyang| Mitsuhashi, Toshiharu| Yamakawa, Michiyo| Sasai, Megumi| Tsuda, Toshihide| Doi, Hiroyuki| Hamada, Jun|
キーワード Elderly Disability Body mass index Long-term care insurance Unhealthy behaviors
発行日 2019-11-29
出版物タイトル PeerJ
7巻
出版者 PeerJ
開始ページ e8146
ISSN 2167-8359
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2019 Liu et al.
論文のバージョン publisher
PubMed ID 31803538
DOI 10.7717/peerj.8146
Web of Science KeyUT 000499696500006
関連URL isVersionOf https://doi.org/10.7717/peerj.8146