著者 Okazaki, Yuki| Furumatsu, Takayuki| Kamatsuki, Yusuke| Okazaki, Yoshiki| Masuda, Shin| Hiranaka, Takaaki| Kodama, Yuya| Miyazawa, Shinichi| Ozaki, Toshifumi|
キーワード Anterior cruciate ligament Lateral meniscus Posterior root tear Transtibial pullout repair Meniscus extrusion
備考 This fulltext is available in Apr. 2021.|
発行日 2020-04-08
出版物タイトル Orthopaedics & Traumatology: Surgery & Research
106巻
3号
出版者 Elsevier
開始ページ 469
終了ページ 473
ISSN 1877-0568
資料タイプ 学術雑誌論文
言語 English
論文のバージョン Author
PubMed ID 32278734
DOI 10.1016/j.otsr.2019.10.022
Web of Science KeyUT 000539660200014
関連URL isVersionOf https://doi.org/10.1016/j.otsr.2019.10.022
JaLCDOI 10.18926/AMO/60373
フルテキストURL 74_4_345.pdf
著者 Tanaka, Takaaki| Furumatsu, Takayuki| Hiranaka, Takaaki| Okazaki, Yuki| Masudaa, Kenji| Senoa, Noritaka| Ozaki, Toshifumi|
抄録 The aim of this study was to evaluate tunnel coalition and inter-tunnel distance by comparing the tibial tunnel position in double-bundle anterior cruciate ligament (ACL) reconstruction performed with a conventional guide versus a posterolateral (PL) divergence (PLD) guide. Subjects were 43 patients (ACL tip aimer: 20 knees; PLD guide: 23 knees) who underwent double-bundle ACL reconstruction between September 2014 and December 2017. In all cases, the tibial tunnel position, tunnel edge distance and tunnel angles were evaluated based on CT images. Clinical outcome was evaluated using the Lachman test, pivot-shift test, and Lysholm score. Tibial tunnel positions were similar between the conventional and PLD guide groups, while tibial tunnel edge distance was significantly less in the conventional group. Tunnel coalition was observed in 5 knees in the conventional and no knees in the PLD guide group. Distance between two tibial tunnel centers was 9.1 mm for the tip aimer, and 10.5 mm for the PLD guide. Creation of the PL tunnel tended to involve insertion from a more medial aspect for the PLD guide group than the conventional guide group. No differences in clinical outcomes were noted. The PLD guide can be used to create anatomically-positioned PL tunnels, and reduce the probability of occurrence of tunnel coalition.
キーワード anterior cruciate ligament reconstruction tibial tunnel position PL divergence guide tunnel coalition
Amo Type Original Article
発行日 2020-08
出版物タイトル Acta Medica Okayama
74巻
4号
出版者 Okayama University Medical School
開始ページ 345
終了ページ 350
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 32843766
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Kamatsuki, Kamatsuki| Sugiu, Kazuhisa| iyazawa, Shinichi| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Kodama, Yuya| Ozaki, Toshifumi|
キーワード Anterior cruciate ligament reconstruction Chondral damage Meniscal repair
備考 This fulltext is available in Feb. 2022.|
発行日 2020-04
出版物タイトル Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
20巻
出版者 Elsevier
開始ページ 1
終了ページ 5
ISSN 22146873
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 32042596
DOI 10.1016/j.asmart.2020.01.001
Web of Science KeyUT 000526087700001
関連URL isVersionOf https://doi.org/10.1016/j.asmart.2020.01.001
著者 Hiranaka, Takaaki| Furumatsu, Takayuki| Kamatsuki, Yusuke| Miyazawa, Shinichi| Okazaki, Yoshiki| Masuda, Shin| Okazaki, Yuki| Kodama, Yuya| Ozaki, Toshifumi|
キーワード Medial meniscus posterior root tear Pullout repair Tibial tunnel Meniscal healing
備考 This fulltext is available in Apr. 2021.|
発行日 2020-04-02
出版物タイトル The Knee
27巻
3号
出版者 Elsevier
開始ページ 899
終了ページ 905
ISSN 0968-0160
NCID AA10996272
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 © 2020 Elsevier B.V.
論文のバージョン author
PubMed ID 32249020
DOI 10.1016/j.knee.2020.02.025
Web of Science KeyUT 000542165100038
関連URL isVersionOf https://doi.org/10.1016/j.knee.2020.02.025
JaLCDOI 10.18926/AMO/41320
フルテキストURL 64_6_351.pdf
著者 Furumatsu, Takayuki| Asahara, Hiroshi|
抄録 Chondrocyte differentiation is the fundamental process in skeletal development. From the mesenchymal condensation of chondroprogenitors to the hypertrophic maturation of chondrocytes, chondrogenesis is sequentially regulated by cross-talk among transcription factors, growth factors, and chromatin structure. The master transcription factor Sry-type HMG box (Sox) 9 has an essential role in the expression of chondrogenic genes through the association with Sox9-binding sites on its target genes. Several transcription factors and coactivators, such as Scleraxis/E47 and p300, cooperatively modulate the Sox9-dependent transcription by interacting with Sox9. The Sox9-related transcriptional apparatus activates its target gene expression through p300-mediated histone acetylation on chromatin. The transforming growth factor (TGF)-β superfamily also plays a key role in chondrocyte differentiation. The TGF-β-regulated Smad3/4 complex activates Sox9-dependent transcription on chromatin by associating with Sox9 itself, and by recruiting p300 onto Sox9. These findings suggest that the epigenetic status including histone modification and chromatin structure, directly influences Sox9-regulated chondrocyte differentiation. In this article, we review the regulators of Sox9 expression itself, modulators of posttranslational Sox9 function, and Sox9-associating factors in the Sox9-dependent epigenetic regulation during chondrogenesis.
キーワード Sox9 TGF-β-Smad3 coactivator p300 scleraxis/E47 chondrogenesis
Amo Type Review
発行日 2010-12
出版物タイトル Acta Medica Okayama
64巻
6号
出版者 Okayama University Medical School
開始ページ 351
終了ページ 357
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 21173804
Web of Science KeyUT 000285664200001
フルテキストURL K002286.pdf
著者 古松 毅之|
発行日 2002-03-25
資料タイプ 学位論文
学位授与番号 甲第2286号
学位授与年月日 2002-03-25
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 Japanese