著者 前田 嘉信|
発行日 1999-06-30
出版物タイトル
資料タイプ 学位論文
著者 Soga, Yoshihiko| Yamasuji, Yoshiko| Kudo, Chieko| Matsuura-Yoshimoto, Kaori| Yamabe, Kokoro| Sugiura, Yuko| Maeda, Yoshinobu| Ishimaru, Fumihiko| Tanimoto, Mitsune| Nishimura, Fusanori| Takashiba, Shogo|
発行日 2009-05
出版物タイトル Supportive Care in Cancer
17巻
5号
資料タイプ 学術雑誌論文
著者 Itou Nao| Maeda Yoshinobu| Hayashi Toyohiko|
発行日 2009-11-11
出版物タイトル Proceedings : Fifth International Workshop on Computational Intelligence & Applications
2009巻
1号
資料タイプ 会議発表論文
著者 Takahashi, Kanayo| Soga, Yoshihiko| Murayama, Yumeno| Udagawa, Mika| Nishimoto, Hitomi| Sugiura, Yuko| Maeda, Yoshinobu| Tanimoto, Mitsune| Takashiba, Shogo|
発行日 2010-01
出版物タイトル Supportive Care in Cancer
18巻
1号
資料タイプ 学術雑誌論文
著者 杉浦 裕子| 曽我 賢彦| 前田 嘉信|
発行日 2010-09-01
出版物タイトル 造血細胞移植now&future
20巻
資料タイプ 一般雑誌記事
著者 Soga, Yoshihiko| Sugiura, Yuko| Takahashi, Kanayo| Nishimoto, Hitomi| Maeda, Yoshinobu| Tanimoto, Mitsune| Takashiba, Shogo|
発行日 2011-02
出版物タイトル Supportive Care in Cancer
19巻
2号
資料タイプ 学術雑誌論文
著者 Soga, Yoshihiko| Maeda, Yoshinobu| Ishimaru, Fumihiko| Tanimoto, Mitsune| Maeda, Hiroshi| Nishimura, Fusanori| Takashiba, Shogo|
発行日 2011-07
出版物タイトル Supportive Care in Cancer
19巻
7号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/47266
フルテキストURL 65_6_403.pdf
著者 Waseda, Koichi| Tanimoto, Yasushi| Ichiba, Shingo| Miyahara, Nobuaki| Murakami, Toshi| Ochi, Nobuaki| Terado, Michihisa| Nagano, Osamu| Maeda, Yoshinobu| Kanehiro, Arihiko| Ujike, Yoshihito| Tanimoto, Mitsune|
抄録 Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT). We here report a case of a 31-year woman with acute lymphatic leukemia, which was treated by chemotherapy and HSCT, and consequently developed BO 2 years after HSCT. A non-tuberculous mycobacterial infection occurred and showed gradual exacerbation. She started taking anti-mycobacterial drugs, but lost appetite, felt tired and finally lost consciousness one month after beginning medication. Arterial blood gas revealed marked hypercapnia. Using extracorporeal life support (ECLS), the carbon dioxide concentration was reduced and her consciousness recovered. To our knowledge, this is the first case in which ECLS was successfully used for hypercapnia in a patient with BO.
キーワード extracorporeal life support hypercapnia bronchiolitis obliterans noninvasive positive pressure ventilation
Amo Type Case Report
発行日 2011-12
出版物タイトル Acta Medica Okayama
65巻
6号
出版者 Okayama University Medical School
開始ページ 403
終了ページ 406
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22189481
Web of Sience KeyUT 000298516900007
著者 朝倉 昇司| 橋本 大吾| 高嶋 秀一郎| 杉山 暖子| 前田 嘉信| 赤司 浩一| 谷本 光音| 豊嶋 崇徳|
発行日 2012-04-01
出版物タイトル 岡山医学会雑誌
124巻
1号
資料タイプ 学術雑誌論文
著者 Sonoi, Norihiro| Soga, Yoshihiko| Maeda, Hiroshi| Ichimura, Koichi| Yoshino, Tadashi| Aoyama, Kazutoshi| Fujii, Nobuharu| Maeda, Yoshinobu| Tanimoto, Mitsune| Logan, Richard| Raber-Durlacher, Judith| Takashiba, Shogo|
発行日 2012-07
出版物タイトル Odontology
100巻
2号
資料タイプ 学術雑誌論文
著者 西森 久和| 前田 嘉信| 谷本 光音|
発行日 2012-12-03
出版物タイトル 岡山医学会雑誌
124巻
3号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/49251
フルテキストURL 67_1_1.pdf
著者 Nishimori, Hisakazu| Maeda, Yoshinobu| Tanimoto, Mitsune|
抄録 Graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation. Chronic GVHD often presents with clinical manifestations that resemble those observed in autoimmune diseases. Standard treatment is 1-2mg/kg/day of prednisone or an equivalent dose of methylprednisolone, with continued administration of a calcineurin inhibitor for steroid sparing. However, the prognosis of steroid-refractory chronic GVHD remains poor. Classically, chronic GVHD was said to involve predominantly Th2 responses. We are now faced with a more complex picture, involving possible roles for thymic dysfunction, transforming growth factor-β (TGF-β) and platelet-derived growth factor (PDGF), B cells and autoantibodies, and Th1/Th2/Th17 cytokines, as well as regulatory T cells (Tregs), in chronic GVHD. More detailed research on the pathophysiology of chronic GVHD may facilitate the establishment of novel strategies for its prevention and treatment.
キーワード chronic GVHD Th17 Am80 regulatory T cell (Treg) steroid-refractory
Amo Type Review
発行日 2013-02
出版物タイトル Acta Medica Okayama
67巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 8
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 23439503
Web of Sience KeyUT 000316829900001
著者 曽我 賢彦| Maeda, Yoshinobu| Tanimoto, Mitsune| Ebinuma, Takayuki| Maeda, Hiroshi| Takashiba, Shogo|
発行日 2013-02
出版物タイトル Supportive Care in Cancer
21巻
2号
資料タイプ 学術雑誌論文
著者 高田 尚良| 佐藤 康晴| 中村 直哉| 徳中 摩美| 三木 由香里| 菊池 イアーラ幸江| 五十嵐 和彦| 伊藤 悦郎| 張替 秀雄| 加藤 省一| 林 詠子| 岡 剛史| 星井 嘉信| 田利 晶| 岡田 裕之| Mohamado, ABD Alkader Lamia| 前田 嘉信| 谷本 光音| 木下 朝博| 吉野 正|
発行日 2013-08-01
出版物タイトル 岡山医学会雑誌
125巻
2号
資料タイプ 学術雑誌論文
著者 Hayashi, Eiko| Takata, Katsuyoshi| Sato, Yasuharu| Tashiro, Yukie| Tachiyama, Yoshiro| Sawada-Kitamura, Seiko| Hiramatsu, Yasushi| Sugiguchi, Shun| Nose, Soichiro| Hirokawa, Mitsuyoshi| Ando, Midori| Abd Mader, Lamia| Maeda, Yoshinobu| Tanimoto, Mitsune| Yoshino, Tadashi|
発行日 2013-09
出版物タイトル Human Pathology
44巻
9号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/51868
フルテキストURL 67_5_319.pdf
著者 Murakawa, Kiminaka| Sato, Tomoaki| Maeda, Yoshinobu| Kitamura, Yoshihisa| Tanimoto, Mitsune| Sendo, Toshiaki|
抄録 Graft-versus-host disease (GVHD) is a major concern in transplantation patients. Gut GVHD is accompanied by diarrhea, abdominal pain, and/or melena. Although oral treatment with corticosteroids (CSs) is effective in treating gut GVHD, it can cause adverse reactions that affect the entire body. Topical administration of CSs can be effective in treating diseases in which lesions are limited locally, because adverse reactions can then be alleviated. In this study, we examine and discuss an enteric-coated beclomethasone dipropionate (BDP) capsule (BDP-EC) formulated at Okayama University Hospital. The BDP-EC did not dissolve in solution 1 (pH1.2), and began disintegrating in solution 2 (pH6.8) after 5min, with a mean dissolution rate at 15min of 85%. We then used the capsule to treat a patient who developed gut GVHD after allogeneic hematopoietic stem cell transplantation. Clinically, the frequency of diarrhea decreased after BDP-EC administration. In addition, we were able to decrease the prednisolone equivalent dose. Symptoms associated with adverse reactions to BDP were not observed during the hospitalization period. These findings suggest that the administration of BDP-EC in the early stages of gut GVHD may allow a reduction in the initial doses of systemic CSs.
キーワード beclomethasone intestinal graft-versus-host disease enteric-coated capsule in-hospital formulation
Amo Type Case Report
発行日 2013-10
出版物タイトル Acta Medica Okayama
67巻
5号
出版者 Okayama University Medical School
開始ページ 319
終了ページ 324
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24145732
Web of Sience KeyUT 000325836100006
著者 Sugiyama, Haruko| Maeda, Yoshinobu| Nishimori, Hisakazu| Yamasuji, Yoshiko| Matsuoka, Ken-ichi| Fujii, Nobuharu| Kondo, Eisei| Shinagawa, Katsuji| Tanaka, Takehiro| Takeuchi, Kengo| Teshima, Takanori| Tanimoto, Mitsune|
発行日 2014-02
出版物タイトル Biology of Blood and Marrow Transplantation
20巻
2号
資料タイプ 学術雑誌論文
Sort Key 10
タイトル(別表記) Molecular targeted therapies in leukemia
フルテキストURL 126_49.pdf
著者 前田 嘉信| 谷本 光音|
キーワード 白血病 分子標的薬 チロシンキナーゼ阻害薬
備考 特集 (Feature Article)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
126巻
1号
出版者 岡山医学会
出版者(別表記) Okayama Medical Association
開始ページ 49
終了ページ 54
ISSN 0030-1558
NCID AN00032489
資料タイプ 学術雑誌論文
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 Japanese
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
査読 有り
DOI 10.4044/joma.126.49
Eprints Journal Name joma
参考文献 1) Kantarjian HM, Talpaz M, O'Brien S, Jones D, Giles F, Garcia-Manero G, Faderl S, Ravandi F, Rios MB, Shan J, Cortes J : Survival benefit with imatinib mesylate versus interferon-alpha-based regimens in newly diagnosed chronic-phase chronic myelogenous leukemia. Blood (2006) 108, 1835-1840. 2) Kantarjian HM, Shah NP, Cortes JE, Baccarani M, Agarwal MB, Undurraga MS, Wang J, Ipiña JJ, Kim DW, Ogura M, Pavlovsky C, Junghanss C, et al. : Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia : 2-year follow-up from a randomized phase 3 trial (DASISION). Blood (2012) 119, 1123-1129. 3) Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Reese SF, Ford JM, Capdeville R, Talpaz M : Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med (2001) 344, 1038-1042. 4) Yanada M, Takeuchi J, Sugiura I, Akiyama H, Usui N, Yagasaki F, Kobayashi T, Ueda Y, Takeuchi M, Miyawaki S, Maruta A, Emi N, et al. : High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia : a phase II study by the Japan Adult Leukemia Study Group. J Clin Oncol (2006) 24, 460-466. 5) Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre P, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DiPersio J, DeAngelo DJ, et al. : A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias. N Engl J Med (2013) 369, 1783-1796. 6) Verstovsek S, Mesa RA, Gotlib J, Levy RS, Gupta V, DiPersio JF, Catalano JV, Deininger M, Miller C, Silver RT, Talpaz M, Winton EF, et al. : A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med (2012) 366, 799-807. 7) Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, et al. : JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med (2012) 366, 787-798. 8) Byrd JC, Furman RR, Coutre SE, Flinn ZW, Burger JA, Blum KA, Grant B, Sharman JP, Coleman M, Wierda WG, Jones JA, Zhao W, et al. : Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med (2013) 369, 32-42. 9) O'Brien S, Furman RR, Coutre SE, Sharman JP, Burger JA, Blum KA, Grant B, Richards DA, Coleman M, Wierda WG, Jones JA, Zhao W, et al. : Ibrutinib as initial therapy for elderly patients with chronic lymphocytic leukaemia or small lymphocytic lymphoma : an open-label, multicentre, phase 1b/2 trial. Lancet Oncol (2014) 15, 48-58. 10) Dietrich S, Glimm H, Andrulis M, von Kalle C, Ho AD, Zenz T : BRAF inhibition in refractory hairy-cell leukemia. N Engl J Med (2012) 366, 2038-2040. 11) Silverman LR, Demakos EP, Peterson BL, Kornblith AB, Holland JC, Odchimar-Reissig R, Stone RM, Nelson D, Powell BL, DeCastro CM, Ellerton J, Larson RA, et al. : Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome : a study of the cancer and leukemia group B. J Clin Oncol (2002) 20, 2429-2440. 12) Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, Schoch R, Gattermann N, Sanz G, List A, Gore SD, Seymour JF, et al. : Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes : a randomised, open-label, phase III study. Lancet Oncol (2009) 10, 223-232.
著者 海老沼 孝至| 曽我 賢彦| Sato, Takamaro| Matsunaga, Kazuyuki| Kudo, Chieko| Maeda, Hiroshi| 前田 嘉信| 谷本 光音| 髙柴 正悟|
発行日 2014-06
出版物タイトル Supportive Care in Cancer
22巻
6号
資料タイプ 学術雑誌論文
著者 Iwatani, Kayoko| Takata, Katsuyoshi| Sato, Yasuharu| Miyata-Takata, Tomoko| Iwaki, Noriko| Cui, Wei| Sawada-Kitamura, Seiko| Sonobe, Hiroshi| Tamura, Maiko| Saito, Katsuhiko| Miyatani, Katsuya| Yamasaki, Rie| Yamadori, Ichiro| Fujii, Nobuharu| Terasaki, Yasushi| Maeda, Yoshinobu| Tanimoto, Mitsune| Nakamura, Naoya| Yoshino, Tadashi|
発行日 2014-07
出版物タイトル Human Pathology
45巻
7号
資料タイプ 学術雑誌論文