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ID 31953
JaLCDOI
フルテキストURL
Thumnail fulltext.pdf 9.13 MB
著者
Tsutsui, Kimiko M. Okayama University
Sano, Kuniaki Okayama University
Tsutsui, Ken Okayama University
抄録

The nuclear matrix is an operationally defined nuclear skeletal structure that is believed to be involved in many nuclear functions including DNA replication, transcription, repair, and prem RNA processing/transport. Until relatively recently, the nuclear matrix was thought to be a rigid and static structure, but it is now thought to be dynamic. This paradigm shift was based in part on the tracking of the intranuclear movement of proteins tagged with fluorochromes. In this review, we attempt to redefine the nuclear matrix in light of recent findings and describe some useful techniques for the dynamic analysis of nuclear function.

キーワード
nuclear matrix
MAR
chromatin
histone modification
topoisomerase
Amo Type
Review
発行日
2005-08
出版物タイトル
Acta Medica Okayama
59巻
4号
出版者
Okayama University Medical School
開始ページ
113
終了ページ
120
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT