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ID 55854
JaLCDOI
フルテキストURL
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著者
Takahashi, Yuko Department of Breast and Endocrine Surgery, Okayama University Hospital
Shien, Tadahiko Department of Breast and Endocrine Surgery, Okayama University Hospital
Sakamoto, Ai Department of Obstetrics and Gynecology, Okayama University Hospital
Tsuyumu, Yuko Department of Nursing, Okayama University Hospital
Yoshioka, Ryo Department of Breast and Endocrine Surgery, Okayama University Hospital
Uno, Maya Department of Breast and Endocrine Surgery, Okayama University Hospital
Hatono, Minami Department of Breast and Endocrine Surgery, Okayama University Hospital
Kochi, Mariko Department of Breast and Endocrine Surgery, Okayama University Hospital
Kawada, Kengo Department of Breast and Endocrine Surgery, Okayama University Hospital
Tsukioki, Takahiro Department of Breast and Endocrine Surgery, Okayama University Hospital
Iwamoto, Takayuki Department of Breast and Endocrine Surgery, Okayama University Hospital
Ikeda, Hirokuni Department of Breast and Endocrine Surgery, Okayama University Hospital
Taira, Naruto Department of Breast and Endocrine Surgery, Okayama University Hospital
Matsuoka, Junji Department of Palliative and Supportive Medicine, Okayama University Hospital
Nakatsuka, Mikiya Department of Obstetrics and Gynecology, Okayama University Hospital
Doihara, Hiroyoshi Department of Breast and Endocrine Surgery, Okayama University Hospital
抄録
Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy. Six (35%) patients underwent oocyte cryopreservation, and 11 (65%) married patients opted for embryo cryopreservation. There were no pregnancies among the patients undergoing oocyte cryopreservation, whereas 3 (27%) of the patients who opted for embryo cryopreservation became pregnant. Two (12%) patients stopped endocrine therapy after 2 years in an effort to become pregnant, but their breast cancers recurred. Though the problem of fertility loss for breast cancer patients is important and we should assess the infertility risk for all patients, we should also consider the prognosis. In June 2016, we launched a prospective multicenter cohort study to evaluate the efficacy and safety of fertility preservation in greater detail.
キーワード
fertility preservation
multidisciplinary
breast cancer
young patients
Amo Type
Original Article
発行日
2018-04
出版物タイトル
Acta Medica Okayama
72巻
2号
出版者
Okayama University Medical School
開始ページ
137
終了ページ
142
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID