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ID 32816
JaLCDOI
フルテキストURL
著者
Ishikawa, Takaki Okayama University
Miyaishi, Satoru Okayama University
Tachibana, Toshiaki Jikei University
Yamamoto, Yuji Okayama University
Ishizu, Hideo Okayama University
抄録

In this study we used paraffin-embedded human pituitary obtained from 248 autopsy cases and identified mixed cell follicles by the immunohistochemical method. We examined the number and size of the mixed cell follicles, and the ratio of each component cell of these follicles, in the anterior pituitary at various age groups. The number of follicles increased with age, and the size of the follicles also tended to enlarge with age. Statistical analysis showed that a high correlation existed between age and the number or the size of the mixed cell-follicles formed by various adenohypophyseal cells. In addition, when the proportions of the different cell types that formed the follicles were examined, sex differences were observed with aging for the GH cells, the PRL cells, and the gonadotroph (GTH) cells, while no changes were observed with aging in both men and women for the ACTH cells and TSH cells. These results indicate that the number, size, and ratio of each component cell of follicles in the anterior pituitary are adequately applicable for the purpose of age estimation in routine forensic medicine.

キーワード
mixed cell-follicle
human anterior pituitary
age estimation
Amo Type
Article
発行日
2003-04
出版物タイトル
Acta Medica Okayama
57巻
2号
出版者
Okayama University Medical School
開始ページ
83
終了ページ
89
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT