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ID 32660
JaLCDOI
フルテキストURL
著者
Takahashi, Michiko Okayama University
Yamada, Gotaro Okayama University
Miyamoto, Rieko Okayama University
Doi, Toshihiko Okayama University
Endo, Hisashi Okayama University
Nishimoto, Hiroshi Okayama University
Fujiki, Shigeatsu Okayama University
Shimomura, Hiroyuki Okayama University
Mizuno, Motowo Okayama University
Tsuji, Takao Okayama University
抄録

We measured hepatitis C virus antibody titers in 13 patients with chronic hepatitis C to determine whether titration of hepatitis C virus antibody was useful or not, to predict and evaluate the efficacy of interferon (IFN) treatment. During administration of IFN, hepatitis C virus titers declined in all patients. Antibody titers performed before treatment as well as just at the end of treatment did not correlate with change of the alanine aminotransferase levels during administration of IFN. Antibody titers declined continuously after treatment in 5 patients with normal alanine amino-transferase levels for over 6 months after discontinuation of IFN. Antibody titers rose again in 6 patients whose alanine aminotransferase levels fluctuated after treatment. An exceptional pattern of change occurred in 2 patients whose antibody titers declined continuously although their alanine aminotransferase levels fluctuated after treatment. Repeated titration of hepatitis C virus antibody appears to be useful for evaluating the long-term efficacy of IFN treatment.

キーワード
titiration of hepatitis C virus antibody
interferon
chronic hepatitis C
efficacy of treatment
Amo Type
Article
発行日
1992-10
出版物タイトル
Acta Medica Okayama
46巻
5号
出版者
Okayama University Medical School
開始ページ
331
終了ページ
336
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT