このエントリーをはてなブックマークに追加
ID 31098
JaLCDOI
フルテキストURL
著者
Takahashi, Michiko Okayama University
Yamada, Gotaro Okayama University
Doi, Toshihiko Okayama Univeristy
Takatani, Masahiro Okayama University
Kishi, Fumitoshi Okayama University
Miyamoto, Rieko Okayama University
Yoshizawa, Hiroshi Hiroshima University
Okamoto, Hiroaki Jichi Medical School
Tsuji, Takao Jichi Medical School
抄録

Hepatitis C virus (HCV)-RNA in the blood was measured by polymerase chain reaction (PCR) in 37 subjects from eight families in which 2 or more persons tested seropositive for antibodies against C100-3 or CP9. HCV-RNA was positive in 17 of 37 subjects. Two or more HCV-RNA-positive subjects were observed in six of the families. Intrafamilial HCV infection was studied by determining the HCV-RNA type (I, II, III or IV) by PCR using type-specific primers. In two families, all of the subjects showed type III infection, and in three other families, all of the subjects showed type II infection, with different types of HCV infections being observed in only one family. The HCV type was uniform in all but one. These findings suggest a possibility of intrafamilial infection between husbands and wives and between members of the same household.

キーワード
HCV
intrafamilial transmission
HCV-RNA genotype
Amo Type
Article
発行日
1994-12
出版物タイトル
Acta Medica Okayama
48巻
6号
出版者
Okayama University Medical School
開始ページ
293
終了ページ
297
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Science KeyUT