このエントリーをはてなブックマークに追加
ID 15883
Eprint ID
15883
フルテキストURL
Thumnail 100_195.pdf 10.1 MB
タイトル(別表記)
Histopathological study of the snapping thumb in infants
著者
滝沢 正 岡山大学整形外科学教室
抄録
Snapping thumb of the infant is usually caused by the disturbance of movement of the flexor tendon in its sheath. Few reports have dealt in detail with the histopathology of the snapping thumb. In the present study, light and electron microscopic observations were carried out on parts of the tendon and tendon sheath excised from snapping thumbs.The tendons and tendon sheaths were obtained from 21 fingers of 19 infants operated on over the last 2 years, under the diagnosis of snapping thumb. There were 10 males and 9 females, ranging in age from 1 to 6 years old. Sectioned samples were studied histochemically, using periodic-acid Schiff, toluidine-blue and high-iron-diamine alcian blue stains. The ultrastructure of the tendon nodule was also studied by scanning and transmission electron microscopy.Increase of the amorphous material and collagen fibrils was observed at the site of tendon nodule formation. The amorphous material was basophilic with hematoxylin-eosin staining, metachromatic with toluidine blue staining, and became dark violet with high-iron-diamine alcian blue, which indicates that it contains acidic mucopolysaccharide with a sulfate radical. The tendon sheath did not contain much amorphous material, but connective tissue cells proliferated. Synovial lining cells were not stratified and no inflammatory cells were found. By scanning electron microscopy, bundles of collagen fibrils of 0.1-0.15μ in diameter, probably newly synthesized, were observed in the middle portion of the tendon nodule. Transmission electron microscopy confirmed that ruthenium-red positive materials exist inside and outside of the fibroblasts. These fibroblasts seem to very actively produce acid mucopolysaccharide and collagen fibrils. Accumulation of the mucopolysaccharide and collagen fibrils by metaplasia of the fibroblasts in the endotenon and epitenon might make the nodule in the tendon. This tendon nodule formation is the primary cause of the snapping thumb of infants.
キーワード
snapping thumb
tendon
infant
histopathology
発行日
1988
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
100巻
1-2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
195
終了ページ
204
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_195/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma