JaLCDOI 10.18926/AMO/32641
フルテキストURL fulltext.pdf
著者 Ozaki, Toshifumi| Inoue, Hajime| Taguchi, Kohji| Sugihara, Shinsuke|
抄録 <p>We compared gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) enhanced T1-weighted images (T1-Gd) with the histopathological findings in 13 patients with bone or soft tissue sarcomas. Signal intensity of the viable tumor tissue was increased in T1-Gd in 92% of the patients. The necrotic or cystic areas in the tumor were not enhanced, rendering them distinctly. The degree of enhancement of the edematous area around the tumor was similar to or more marked than that of the tumor in 54% of the patients. Area showing inflammatory cells infiltration and edematous areas in the tumor tissue were also enhanced. Thus, the effect of preoperative chemotherapy in tumor tissues other than necrotic and cystic areas tended to be underestimated in T1-Gd. Its effect should be comprehensively evaluated based on not only T1-Gd but also T2-weighted images and findings of other imaging techniques.</p>
キーワード gadolinium diethylenetriaminepentaacetic acid(DTPA) magnetic resonance(MR) bone neoplasms soft tissue neoplasms
Amo Type Article
発行日 1992-12
出版物タイトル Acta Medica Okayama
46巻
6号
出版者 Okayama University Medical School
開始ページ 471
終了ページ 477
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 1485542
Web of Sience KeyUT A1992KE49600010
JaLCDOI 10.18926/AMO/30472
フルテキストURL fulltext.pdf
著者 Uchida, Yoichiro| Kawai, Akira| Taguchi, Kohji| Yokoi, Tadashi| Pu, Jian| Inoue, Hajime|
抄録 <p>We conducted a clinicopathological analysis of chondrosarcomas in 17 patients treated in our institute. The 5- and 10-year overall survival rates of the patients were 72.3% and 61.9%, respectively. The significant prognostic factors were size and histologic grade of the tumor. Sex, age, location of the primary tumor, or the presence of a preceding exostosis did not affect the treatment results significantly. Chondrosarcomas of histologic grades I and II did not metastasize, while all grade III and dedifferentiated chondrosarcomas metastasized to the lung. The local recurrence rate depended on the surgical margin. Wide excision with an adequate surgical margin is important to achieve local control of the chondrosarcoma.</p>
キーワード chondrosarcoma pathological grading prognostic factors
Amo Type Article
発行日 1996-08
出版物タイトル Acta Medica Okayama
50巻
4号
出版者 Okayama University Medical School
開始ページ 191
終了ページ 196
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 8874580
Web of Sience KeyUT A1996VE60800002
JaLCDOI 10.18926/AMO/30784
フルテキストURL fulltext.pdf
著者 Kunisada, Toshiyuki| Kawai, Akira| Ozaki, Toshifumi| Sugihara, Shinsuke| Taguchi, Kohji| Inoue, Hajime|
抄録 <p>In this study, we reviewed the clinical features of 11 patients with malignant schwannoma who were treated in our institute. Five patients had coexistent von Recklinghausen's disease and one of them showed multifocal occurrence. Patients with the centrally located tumors had a poorer prognosis than those with the others. The overall 3-year survival rate was 36%; 40% in patients with von Recklinghausen's disease and 33% in the others. At the time of the last follow-up, 9 patients had died of the tumor, one continued to be tumor free, and one was alive with tumor. Postoperative local recurrence developed in 5 patients (45%); 4 out of 6 patients (67%) who underwent a marginal excision and one out of 3 (33%) who underwent primary amputation. There was no local recurrence in patients after a wide excision with at least 3cm of normal tissue removed surrounding the tumor in all directions. Nine patients (82%) developed pulmonary metastasis. The effect of adjuvant chemotherapy was not clear in this study. The high risk of pulmonary metastasis in this disease indicates the necessity of more effective adjuvant chemotherapy.</p>
キーワード malignant schwannoma clinical analysis von Recklinghausen's disease
Amo Type Article
発行日 1997-04
出版物タイトル Acta Medica Okayama
51巻
2号
出版者 Okayama University Medical School
開始ページ 87
終了ページ 92
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 9142345
Web of Sience KeyUT A1997WX19600005
著者 Hamazaki, Yukio| Ogawa, Katsuo| Tsutsumi, Akira| Ohmori, Masaki| Taguchi, Kohji|
発行日 1963-02
出版物タイトル Acta Medicinae Okayama
17巻
1号
資料タイプ 学術雑誌論文
著者 Takechi, Hideo| Taguchi, Kohji|
発行日 1978-10
出版物タイトル Acta Medica Okayama
32巻
5号
資料タイプ 学術雑誌論文