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ID 55453
フルテキストURL
著者
Huang, Xin-Yuan Institute of Biological and Environmental Sciences, University of Aberdeen
Deng, Fenglin Institute of Plant Science and Resources, Okayama University
Yamaji, Naoki Institute of Plant Science and Resources, Okayama University
Pinson, Shannon R.M. USDA-ARS Dale Bumpers National Rice Research Center
Fujii-Kashino, Miho Institute of Plant Science and Resources, Okayama University
Danku, John Institute of Biological and Environmental Sciences, University of Aberdeen
Douglas, Alex
Guerinot, Mary Lou Department of Biological Sciences, Dartmouth College
Salt, David E. Institute of Biological and Environmental Sciences, University of Aberdeen
Ma, Jian Feng Institute of Plant Science and Resources, Okayama University
抄録
Rice is a major source of calories and mineral nutrients for over half the world's human population. However, little is known in rice about the genetic basis of variation in accumulation of copper (Cu), an essential but potentially toxic nutrient. Here we identify OsHMA4 as the likely causal gene of a quantitative trait locus controlling Cu accumulation in rice grain. We provide evidence that OsHMA4 functions to sequester Cu into root vacuoles, limiting Cu accumulation in the grain. The difference in grain Cu accumulation is most likely attributed to a single amino acid substitution that leads to different OsHMA4 transport activity. The allele associated with low grain Cu was found in 67 of the 1,367 rice accessions investigated. Identification of natural allelic variation in OsHMA4 may facilitate the development of rice varieties with grain Cu concentrations tuned to both the concentration of Cu in the soil and dietary needs.
キーワード
Genetic variation
Natural variation in plants
Quantitative trait
Rice
備考
This is an article published by Nature Publishing Group
発行日
2016-07
出版物タイトル
Nature Communications
7巻
出版者
Nature Publishing Group
開始ページ
12138
ISSN
2041-1723
NCID
AA12645905
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
著作権者
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン
publisher
PubMed ID
DOI
Web of Sience KeyUT
関連URL
https://doi.org/10.1038/ncomms12138