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ID 55446
JaLCDOI
フルテキストURL
Thumnail 71_5_453.pdf 1.91 MB
著者
Taniguchi, Akihiko Department of Allergy and Respiratory Medicine, Okayama University Hospital Kaken ID
Miyahara, Nobuaki Department of Allergy and Respiratory Medicine, Okayama University Hospital
Oda, Naohiro Department of Allergy and Respiratory Medicine, Okayama University Hospital
Morichika, Daisuke Department of Allergy and Respiratory Medicine, Okayama University Hospital
Ichihara, Eiki Department of Allergy and Respiratory Medicine, Okayama University Hospital Kaken ID
Oze, Isao Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute
Tanimoto, Yasushi National Hospital Organization Minami-Okayama Medical Center
Ichikawa, Hirohisa Department of Respiratory Medicine, KKR Takamatsu Hospital
Fujii, Utako Department of Allergy and Respiratory Medicine, Okayama University Hospital
Tanimoto, Mitsune Department of Allergy and Respiratory Medicine, Okayama University Hospital Kaken ID publons researchmap
Kanehiro, Arihiko Department of Allergy and Respiratory Medicine, Okayama University Hospital
Kiura, Katsuyuki Department of Allergy and Respiratory Medicine, Okayama University Hospital Kaken ID researchmap
抄録
Although recent retrospective studies suggested that the use of β-blockers appears to help improve the mortality rate and decrease the rate of exacerbation in chronic obstructive pulmonary disease (COPD) patients with heart failure, the effects of β-blockers on COPD patients without heart failure have not been established. Based on previous reports, we have launched a multicenter, prospective, single-arm phase II study to evaluate the preventive effect of the cardioselective β-blocker bisoprolol in COPD exacerbation, in Japanese individuals with moderate-to-severe COPD who do not have heart failure but do have hypertension requiring the use of medication. The primary endpoint is the rate of mild-to-severe COPD exacerbation. The results of this study will clarify whether bisoprolol can prevent exacerbation in COPD patients without heart failure.
キーワード
chronic obstructive pulmonary disease
β-blocker
bisoprolol
exacerbation
heart failure
Amo Type
Clinical Study Protocol
発行日
2017-10
出版物タイトル
Acta Medica Okayama
71巻
5号
出版者
Okayama University Medical School
開始ページ
453
終了ページ
457
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
著作権者
CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン
publisher
査読
有り
PubMed ID