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ID 32277
JaLCDOI
フルテキストURL
著者
Karakas, Zeynep University of Isatanbul
Agaoglu, Leyla University of Isatanbul
Biner, Betul University of Isatanbul
Devecioglu, Omer University of Isatanbul
Anak, Sema University of Isatanbul
Yalman, Nevin University of Isatanbul
Unuvar, Aysegul University of Isatanbul
Celik, Alaattin University of Isatanbul
Gedikoglu, Gunduz University of Isatanbul
抄録

Fifty-one children (median age: 4.5 years; 4 months-16 years) diagnosed with rhabdomyosarcoma were treated in our center between 1980-1999. The primary sites were head and neck in 31.4%, the genito-urinary system in 21.6%, and extremities in 9.8% of the patients. The histopathologic subtypes were embryonal in 80.4%, alveolar in 9.8%, and undifferentiated in 9.8%. The majority of the patients were considered group III (47%) and group IV (25.5%) according the criteria of the Intergroup Rhabdomyosarcoma Study (IRS). Primary total tumour resection was performed in only 27.5% of the patients. The patients were treated with assigned regimens of IRS II and IRS III protocols. Radiotherapy was applied to 92.1% of the patients. Thirty-four patients (66.7%) were lost to follow up, and of the remaining 17 patients, 7 patients (41.2%) died, relapse occurred in 9 patients (52.9%) and 10 patients (58.8%) are alive. The percentage of cases lost to follow up during the first 10 years and the following 9 years of the study were 77.4% and 50%, respectively. In compliance with cancer treatment remains a major problem in developing countries.

キーワード
rhabdomyosarcoma
pediatric onocology
chemotherapy
Amo Type
Article
発行日
2000-08
出版物タイトル
Acta Medica Okayama
54巻
4号
出版者
Okayama University Medical School
開始ページ
173
終了ページ
177
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT