JaLCDOI 10.18926/AMO/55854
フルテキストURL 72_2_137.pdf
著者 Takahashi, Yuko| Shien, Tadahiko| Sakamoto, Ai| Tsuyumu, Yuko| Yoshioka, Ryo| Uno, Maya| Hatono, Minami| Kochi, Mariko| Kawada, Kengo| Tsukioki, Takahiro| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Matsuoka, Junji| Nakatsuka, Mikiya| Doihara, Hiroyoshi|
抄録 Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy. Six (35%) patients underwent oocyte cryopreservation, and 11 (65%) married patients opted for embryo cryopreservation. There were no pregnancies among the patients undergoing oocyte cryopreservation, whereas 3 (27%) of the patients who opted for embryo cryopreservation became pregnant. Two (12%) patients stopped endocrine therapy after 2 years in an effort to become pregnant, but their breast cancers recurred. Though the problem of fertility loss for breast cancer patients is important and we should assess the infertility risk for all patients, we should also consider the prognosis. In June 2016, we launched a prospective multicenter cohort study to evaluate the efficacy and safety of fertility preservation in greater detail.
キーワード fertility preservation multidisciplinary breast cancer young patients
Amo Type Original Article
発行日 2018-04
出版物タイトル Acta Medica Okayama
72巻
2号
出版者 Okayama University Medical School
開始ページ 137
終了ページ 142
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29674762
フルテキストURL BreastCancer_24_4_593.pdf BreastCancer_24_4_593_tbl_fig.pdf
著者 Saiga, Miho| Taira, Naruto| Kimata, Yoshihiro| Watanabe, Satoko| Mukai, Yuko| Shimozuma, Kojiro| Mizoo, Taeko| Nogami, Tomohiro| Iwamoto, Takayuki| Motoki, Takayuki| Shien, Tadahiko| Matsuoka, Junji| Doihara, Hiroyoshi|
キーワード BREAST-Q Breast cancer Breast reconstruction Health-related quality of life Satisfaction
発行日 2017-03
出版物タイトル Breast Cancer
24巻
2号
出版者 Japanese Breast Cancer Society
開始ページ 288
終了ページ 298
ISSN 1340-6868
NCID AA1103354X
資料タイプ 学術雑誌論文
言語 English
OAI-PMH Set 岡山大学
著作権者 https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン author
PubMed ID 27179527
DOI 10.1007/s12282-016-0703-6
Web of Sience KeyUT 000395524900012
関連URL isVerionOf https://doi.org/10.1007/s12282-016-0703-6