JaLCDOI 10.18926/AMO/31985
フルテキストURL fulltext.pdf
著者 Camdeviren, Handan| Mendes, Mehmet| Ozkan, M. Muhip| Toros, Fevziye| Sasmaz, Tayyar| Oner, Seva|
抄録 <p>We used a regression tree method (RTM) to determine risks of depression in children/adolescents. The survey records of 4,143 children/adolescents in a study based in Mersin, Turkey served as data in this study, and multi-step, stratified, and cluster sampling were used. Effects of 24 variables (sex, smoking, parental problems, etc.) were evaluated on depression scores. The Child Beck Depression Inventory (CBDI) was used to determine the level of depression. Subjects were into 12 different groups based on magnitudes of mean depression scores. The interactions among 7 variables determined to be risk factors are shown on a schema. The STATISTICA (ver.6.0) package program was used for all computations. Although traditional statistical methods have often been used for analysis in this field, such approaches are associated with certain disadvantages such as missing values, ignorance of interaction effects, or restriction of the shape of the distribution. To avoid such disadvantages, we therefore suggest the use of the RTM in studies involving numerical-based outcome variables and for the investigation of a large number of variables and it may be more effective than traditional statistical methods in epidemiological studies which determine risk factors.</p>
キーワード children and adolescents Beck depression inventory classification and regression trees cross-yalidation diagnostic models
Amo Type Article
発行日 2005-02
出版物タイトル Acta Medica Okayama
59巻
1号
出版者 Okayama University Medical School
開始ページ 19
終了ページ 26
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 15902995
Web of Sience KeyUT 000227263300003
JaLCDOI 10.18926/AMO/31967
フルテキストURL fulltext.pdf
著者 Kurtoglu, Zeliha| Ozturk, Ahmet Hakan| Bagdatoglu, Celal| Polat, Gurbuz| Aktekin, Mustafa| Uzmansel, Deniz| Camdeviren, Handan| Bagdatoglu, Ozlen| Sargon, Mustafa|
抄録 <p>In this study, we evaluated the effects of trapidil on crush injury by monitoring nitric oxide, malondialdehyde and transforming growth factor-Beta2 levels and by transmission electron microscopy in the rat sciatic nerve. The sciatic nerve was compressed for 20 sec by using a jewelers forceps. Trapidil treatment groups were administrated a single dose of trapidil (8 mg/kg) intraperitoneally just after the injury. The crush and crush + trapidil treatment groups were evaluated on the 2nd, 7th, 15th, 30th and 45th days of the post-crush period. On the 7th and 15th days, damage in thin and thick myelinated axons, endoneural edema and mitochondrial swelling were less severe in the trapidil group histopathologically. These findings supported the idea that trapidil prevented cell damage and edema at the injury site. Day/group interaction with regard to serum nitric oxide, malondialdehyde and transforming growth factor-Beta2 levels did not show significant changes.</p>
キーワード trapidil crush injury peripheral nerve electron microscopy nitric oxide
Amo Type Article
発行日 2005-04
出版物タイトル Acta Medica Okayama
59巻
2号
出版者 Okayama University Medical School
開始ページ 37
終了ページ 44
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 English
論文のバージョン publisher
査読 有り
PubMed ID 16049553
Web of Sience KeyUT 000228590000001