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ID 18336
Eprint ID
18336
フルテキストURL
Thumnail 77_1077.pdf 546 KB
タイトル(別表記)
Clinical Significance of Mesobilirubinogen 2. Significance of urinary mesobilirubinogen in experimental liver injury
著者
谷 幹彦 岡山大学医学部第一内科教室
抄録
After inducing experimental liver injury in normal adult rabbits by the injection of chloroform, carbon tetrachloride, or allyl-formate the relationship between the mesobiliviolin reaction at the time when urinary urobilinogen is positive and the results of various examinations on liver function was studied simultaneously, and the following results were obtained. 1. There is found no proportional relation between the concentration of urinary urobilinogen and the positivity of mesobiliviolin reaction, and when urobilinogen is at normal level, the mesobiliviolin reaction proves to be always negative. 2. The histological pictures of the liver when it is mesobiliviolin positive reveal a strong stellate reaction, showing a marked correlation, but there is not necessarily their correlation with the degree of liver cell degeneration. 3. At the time when mesobiliviolin reaction is positive, Takata's reaction and CCF give the rate of 94.1% and 88.2% respectively, showing a marked correlation with one another. TTT gives the rate of 64.4%, being somewhat lower, but there can be observed no correlation between the serum bilirubin level and the positivity to the mesobiliviolin reaction. The degree of BSP injury is 82.3%, showing a good correlation. On the other hand, between the urinary urobilinogen content and these liver functions there is no appreciable correlation. 4. Therefore, even assuming that mesobilirubinogen is disposed of by the liver endothelial system, it represents a more marked injury of the liver than urobilinogen.
発行日
1965-07-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
77巻
7号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1077
終了ページ
1086
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/77/7/77_7_1077/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma