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ID 18335
Eprint ID
18335
フルテキストURL
Thumnail 77_1067.pdf 1.84 MB
タイトル(別表記)
Clinical Significance of Mesobilirubinogen 1. Significance of urinary mesobilirubinogen in various diseases
著者
谷 幹彦 岡山大学医学部第一内科教室
抄録
With the purpose to ascertain clinical significance of urinary mesobilirubinogen in various disease, the author studied by means of the mesobiliviolin reaction changes of mesobilirubinogen contents in the urine of those patients suffering from hepatitis, liver cirrhosis, lung tuberculosis, constipation, and others, who proved positive to the urobilinogen reaction. Simultaneously their liver functions were examined. The results of this study are summarized as follows. 1. It is best to determine the mesobiliviolin reaction six minutes after boiling, and the isolation of mesobiliviolin can be achieved most adequately by column chromatography. By this method there will be yielded some substances other than mesobiliviolin as the by-products. 2. The positive rate to the mesobiliviolin reaction is 50 % in liver cirrhosis, 40 % in serum hepatitis, and 11.8 % in chronic hepatitis, indicating that the severer the injury of liver parenchyma, the higher is the positive rate. In the case of normal persons and those with constipation the reaction is negative. In addition, no positive case can be recognized in those cases with less than 0.40mg/dl of urobilinogen. 3. There cannot be observed any proportional relation between the urobilinogen concentration and the mesobilirubinogen content. 4. In those cases proved to be positive to the mesobiliviolin reaction the positive rate of various examinations on liver function was 50-62.5%, whereas those positive to urobilinogen it was 15.5%-25.8%. 5. It is assumed that the positivity to urinary mesobilirubinogen reaction is of a great importance for determining the disorder in the liver function.
発行日
1965-07-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
77巻
7号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1067
終了ページ
1076
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/77/7/77_7_1067/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma