JaLCDOI 10.18926/21195
タイトル(別表記) The treatment of rheumatoid arthritis with D-penicillamine. Preliminary report
フルテキストURL pitsr_047_069_075.pdf
著者 石井 廣文| 高杉 潔| 北山 稔| 森永 寛|
抄録 Twenty patients with classical or definite rheumatoid arthritis were treated with D-Penicillamine. Favorable responses were observed in 75% of the patients. Significant improvement in clinical parameters, such as ESR, CRP, titers of rheumatoid factor and so forth, was noticed in twenty weeks of treatment. Withdrawal from penicillamine treatment was necessitated in four patients because of adverse reactions to the drug. Untoward effects included skin rash (most frequent), pruritis and loss of taste. From this preliminary study we presume that in earlier cases in which rheumatoid lesions may be reversible, more favorable clinical effects would be expected from this agent.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
開始ページ 69
終了ページ 75
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310960
JaLCDOI 10.18926/21182
タイトル(別表記) Prevalence of periCardial effusion in patients with rheumatoid arthritis -An echocardiographic study-
フルテキストURL pitsr_048_049_054.pdf
著者 石井 廣文| 道明 道弘| 田中 淳太郎| 高杉 潔|
抄録 In order to determine the incidence of pericardial effusion in rheumatoid arthritis (RA), echocardiographic studies were performed on patients with classical or definite RA as determined by ARA criteria, none of whom showed any clinical cardiac symptoms at the time of examination. Of 50 RA patients studied so far, fifteen (30%) showed evidence of posterior pericardial effusion, as recorded on the strip charts. Additionally, in one full-blown case of rheumatoid vasculitis, massive accumulation of pericardial fluid was demonstrable. Compared to those without pericardial effusion, patients shown to have pericardial fluid tended to have decreased RBC, Hct, Hgb, serum protein concentration and increased ESR. The statistical difference between the two groups was significant (P<0.005). The most conspicuous difference between the two, however, was noted in the degree of hypoalbuminemia that is more profound in the effusion positive group (P<0.005). The possible cause of fluid retention in the pericardial cavity in RA was briefly discussed.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
開始ページ 49
終了ページ 54
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310937