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ID 16275
Eprint ID
16275
フルテキストURL
Thumnail 95_233.pdf 857 KB
タイトル(別表記)
Function of peripheral blood lymphocytes in patients with systemic lupus erythematosus. Part 1. Characteristics of spontaneously proliferating cells
著者
盛政 公明 岡山大学医学部第三内科学教室
抄録
Increased 3H-Thymidine(3H-TdR) uptake was noticed when peripheral blood mononuclear cells (MNC) from systemic lupus erythematosus(SLE) patients were cultured without any mitogenic stimulation. The peak of 3H-TdR uptake was found immediately after transfering the cells to in vitro culture. DNA synthesizing cells were observed directly by means of autoradiography by pulsing with 3H-TdR for 4 hours. Therefore, it was presumed that there were some MNC in the peripheral blood from SLE patients which were already triggered to proliferate in vivo. These spontaneously proliferating MNC were found to fractionate into a nonadherent, non-E-rosette forming and surface immunoglobulin negative cell population, the so called null cell population. These results suggest that there were activated MNC in the peripheral blood from patients with SLE which fractionated into a null cell population.
キーワード
systemic lupus erythematosus
peripheral blood lymphocytes
spontaneously proliferating cells
null cell fraction
発行日
1983-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
95巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
233
終了ページ
242
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/95/3-4/95_3-4_233/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma