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ID 13805
Eprint ID
13805
フルテキストURL
Thumnail 106_883.pdf 1.47 MB
タイトル(別表記)
Xanthoma cells in sputa of patients with chronic obstructive lung diseases
著者
河内 和久 岡山大学医学部第二内科学教室
抄録
Alveolar macrophages attack various foreign bodies inspired through the airway and destroy cell debris. Furthermore, a part of the surfactant produced by alveolar epithelium would be phagocytized by alveolar macrophages forming foamy cells in lung tissue. These formy cells could be detected by oil red O staining as xanthoma cells in sputa of patients with airway diseases. Therefore, xanthoma cells in sputa of patients with DPB, chronic bronchitis and bronchial asthma were evaluated to clarify the role in the pathogenesis of these respiratory diseases. All patients with DBP expectorated enormous amounts of xanthoma cells in sputa while 88% of the patients with chronic bronchitis and 41% of those with bronchial asthma had sputa containing xanthoma cells in a smaller number than DBP. Increased xanthoma cells were shown in DPB with longer disease duration, lower vital capacity, lower atrerial blood oxygen pressure, and pseudomonas infection. However, extreme obstruction of small airway diminished xanthoma cells in sputa. Xanthoma cells were shown in bronchial asthma especially in late onset and intractable asthmatics. These findings indicate that xanthoma cells in sputa reflect the existence of organic changes in the small airway which disturb the drainage of surfactant from alveolar area to bronchial trees.
キーワード
びまん性汎細気管支炎
気管支喘息
喀痰
oil red O 染色
xanthoma cell
備考
原著
発行日
1994-08
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
106巻
7-8号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
883
終了ページ
892
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/106/7-8/106_7-8_883/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/index.html
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma