JaLCDOI 10.18926/21120
タイトル(別表記) Clinical effects of swimming training in a hot spring pool on bronchial asthma
フルテキストURL 053_035_043.pdf
著者 谷崎 勝朗| 駒越 春樹| 周藤 真康| 村嶋 誠| 岡田 千春| 森永 寛| 小橋 秀敏| 多田 慎也| 木村 郁郎|
抄録 Five severe bronchial asthma patients with glucocorticoid therapy have had free swimming training in the hot spring pool at Misasa Medical Branch. The clinical effect of the swimming training was evaluated after 3 months' training. 1. A slight increase in pulse rate and blood pressure was observed immediately after 30 minutes, swimming, although no significant increase in the two parameters was shown 30 min. after the training. 2. No significant fall in ventilatory function tests such as % FVC, FEV(1.0)%, V(50) and V(25) was demonstrated following the swimming training in a hot spring pool. The results suggest that the free swimming training in a hot spring pool does not induce bronchoconstriction. 3. Clinical efficacy of the swimming training on bronchial asthma was evaluated according to a treatment score, an attack score and an asthmatic score. These scores were decreased during the swimming training. The results obtained in this study showed that free swimming training in a hot spring pool is one of the most suitable therapies for severe bronchial asthma patients.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 35
終了ページ 43
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321171
JaLCDOI 10.18926/40077
タイトル(別表記) A FORTRAN data processing system for the epidemiological data on rheumatic diseases - Part 1. Basic programs for deposit and retrieval of data
フルテキストURL 046_045_059.pdf
著者 伊東 恵子| 北山 稔| 森永 寛| 松井 義人|
抄録 A set of FORTRAN programs for small computer is described for deposit and retrieval of the epidemiological data, which have been compiled at the Kami-hojo-cho district in Feb. 1972and Feb. 1975. A data file is constructed on a magnetic disk. The following items are recorded and registered on the disk for every person: identification number, full name in Japanese alphabet, sex, date of birth, weight, height, blood pressures, chemical characterics of blood serum and urine, and various complaints of clinical significance (fever, morning stiffness, arthralgia, joint swelling, myalgia, cutaneous rash, aphthous stomatitis, dry eyes, dry mouth, joint deformity, subcutaneous nodules, lymph and parotid gland enlargement, struma, heart murmur, and neulogical findings). All information per one person requires only two IBM cards due to compact encoding of original records. The encode-decode procedures are explained also in the text.
出版物タイトル 岡山大学温泉研究所報告
発行日 1977-03-25
46巻
開始ページ 45
終了ページ 59
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321122
JaLCDOI 10.18926/21181
タイトル(別表記) A case of SLE with non-erosive joint deformity -Jaccoud's type arthropathy-
フルテキストURL 048_043_048.pdf
著者 田中 淳太郎| 道明 道弘| 高杉 潔| 入野 昭三| 森永 寛|
抄録 A case of SLE in a twenty-eight year old woman, who had polyarthritis with non-erosive joint deformity, was reported. Differential diagnosis in this case included (1) rheumatoid arthritis (2) postrheumatic fever arthritis (Jaccoud's arthritis) and (3) the overlap syndrome between SLE and rheumatoid arthritis. Laboratory findings on this patient and review on literature, however, strongly suggested that this lady had been suffering from Jaccoud's type arthropathy of SLE. Corticosteroid therapy was initiated and the clinical course of the patient thereafter has been more than favorable.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
48巻
開始ページ 43
終了ページ 48
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 40000321139
JaLCDOI 10.18926/40322
タイトル(別表記) THE CLINICAL STUDIES OF RHEUMATOID ARTHRITIS (I)
フルテキストURL 016_035_048.pdf
著者 森永 寛|
抄録 The value of spa treatment of rheumatic disease is an established feature of medical management based on experiences for many centuries. The author has been practising the balneotherapy of rheumatic diseases at Misasa Spa for several years, and has found this therapy efficacious in many cases in relieving the anemia that accompanies rheumatoid arthritis. For this reason, the author is investigating the metabolism of iron in rheumatic anemia, which is expected to occur in the course of the spa treatment. In this report, the results of clinical examinations of 24 patients with rheumatoid arthritis, of the type (2. 2. 2.) Polyarthritis systemica chronica (in Prof. Kodama's classification of arthritis), are described. I. Some observations of anemia in rheumatoid arthritis 1. The peripheral blood The number of erythrocytes is 266×10(4)~455×10(4)/c. mm. (average: (381±32)×10(4)/c. mm.), Hb-content : 55~90% (average : 76±5.8%), and the color index is about 1.0. The anemia of rheumatic disease treated is mostly normochromic. The white blood count is between 3240 and 13300/c. mm. (average: 6421±955/c. mm. ), and the number of the leucocytes in 80% of the cases ranges within the normal limits. Eosinophilia is observed in 15% of the cases. 2. Anemia-producing substance in the serum of rheumatoid arthritis When serum from rheumatoid arthritis patients was injected into rabbits, the number of erythrocytes and the hemoglobin -content of the rabbits was found to decrease markedly for 2~6hours after the injection. But no such effect was observed when the serum of healthy subjects was injected. From this, the author presumes the presence of an anemia-producing substance in the serum of rheumatoid arthritis. The nature of this substance in now under investigation. II. Clinical-biochemical studies 3. Gastric acidity of rheumatic patients Of 7 cases examined, anacidity of gastric juice was observed in 2 cases, subacidity in other 2 cases and normacidity in the remaining 3 cases. Thus, a decrease in the gastric acidity was found to occur in 57% of the cases. 4. Takata-serum-test and sedimentation rate It is said that the sedimentation rate and the Weltmann-reaction are very sensitive indicators of the extent of the activity of rheumatic disease. The Takata-serum-test was applied in 18 cases and was found to give positive results in 10 cases (55%). The sedimentation rate was found to increase in 17 of 20 cases (85%). 5. Blood uric acid As is well known, the concentration of uric acid is abnormally high in the blood of patients with gout; while, according to the literature, the blood uric acid levels of patients with rheumatoid arthritis range within the normal limits. The author, using the method of Benedict, obtained the following results for blood uric acid in 14 normal subjects in fasting state: Range - 2.30~3.47mg./dl. , 5% rejection limit -- 1.97~3.68mg./dl. In 5 of 7 cases of rheumatoid arthritis, the blood uric acid levels were shown to be above the upper limit of the normal range, but the concentrations of blood uric acid of non-rheumatic joint diseases and neuralgias were mostly within the normal range. 6. Blood sugar The fasting blood sugar levels of rheumatoid patients ranged from 82 to 1l0mg./dl. (average : 100mg./dl.), higher than the levels of healthy subjects (78~108mg./dl., average : 90mg./dl.). The intravenously injected glucose load test was applied to 8 rheumatoid patients. A solution of 40 ml. of 20% glucose was injected into a fasting subject for 2 minutes. Blood samples were taken before the injection, 3 minutes after the injection, and at each subsequent 10 minute-interval for 70 minutes. The glucose tolerance curves in 5 of these cases were found to be out of the normal range. It is to be noticed that the average blood sugar for rheumatoid arthritis is similar to the curve for liver disease. 7. Serum alkaline phosphatase activity and serum phosphorus The method of Taussky-Shorr was used for the determination of the level of alkaline phosphatase activity and inorganic phosphate in the serum. The alkaline phosphatase activity of 11 normal individuals ranged from 1.4 to 6.4 Shinowara-Jones-Rheinhart units/dl. (5% rejection limit), while in 4 of 8 cases of rheumatoid arthritis, it was of abnormally high levels. The concentration of inorganic phosphate in the serum of 12 normal subjects ranged from 2.9 to 5.0mg. /dl. (5% rejection limit), while in 3 cases of rheumatoid patients, it showed higher levels than normal. 8. Total cholesterol in serum The total cholesterol in the serum of fasting normal individuals was measured by Bloor's method, and the concentration was found to range from 124 to 188mg./dl. (rejection limit of 5% level of significance), and the total cholesterol in the serum of rheumatoid arthritis to be abnormally high in concentration in 6 of 7 cases. The liver function was evaluated by the Takata-serum-test, the test of fasting blood sugar levels, the glucose load test, and the test of serum alkaline phosphatase activity; and from this the hepatic dysfunction was found to occur in rheumatoid arthritis patients in about 50% of the cases examined. Disturbances in the protein, fat, and carbohydrate metabolism were also found to occur. The above-mentioned findings indicate that rheumatoid arthritis is not only a disease of the joints, but also a general and systemic illness. Attention must accordingly be given to the general condition of the patient in the treatment of rheumatic disease.
出版物タイトル 岡山大学温泉研究所報告
発行日 1956-01
16巻
開始ページ 35
終了ページ 48
ISSN 0369-7142
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/40318
言語 Japanese
論文のバージョン publisher
NAID 40017532470
JaLCDOI 10.18926/19625
タイトル(別表記) STUDIES ON BALNEOTHERAPY OF DIABETES MELLITUS (Ⅱ). EFFECT OF INTERNAL USE OF GERO HOT SPRING ON THE ALIMENTARY HYPERGLYCEMIA IN ALLOXAN-DIABETIC RABBITS
フルテキストURL 015_048_052.pdf
著者 森永 寛|
抄録 The author investigated the effect of the internal use of the hot spring water of Gero (Gifu Prefecture, Japan), which contained Cl' 167 mg./L., HCO(3)' 66.0 mg./L. and titrated sulphur 0.6 mg./L. (pH: 6.2) at the time of this experiment, upon the alimentary hyperglycemia in alloxan-diabetic rabbits. 1. The author injected alloxan of 150 mg. per kg. of body weight intravenously into normal rabbits and performed the experiment 5~6 weeks after the injection. At the time of the experiment, the fasting blood sugar levels of alloxan-diabetic rabbits ranged from 107 to 211 mg./dl. (170 mg./dl. on the average). 2. Thirty ml. of 10% glucose solution in thermal water or in plain water per kg. of body weight was administered to the rabbits by stomach tube, and blood sugar level was determined before and 1/2, 1, 2, 3, 4 and 5 hours after the administration. The rejection interval (5%) of the glucose tolerance in 17 normal rabbits is shown in Fig. Ⅰ. Glucose tolerance curves of these alloxan-diabetic rabbits were out of the limit of the normal range. 3. Gero Hot Spring water had no inhibitory action upon the alimentary hyperglycemia of alloxan-diabetic rabbits.
出版物タイトル 岡山大学温泉研究所報告
発行日 1955-03-25
15巻
開始ページ 48
終了ページ 52
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002309141
JaLCDOI 10.18926/15532
タイトル(別表記) STUDIES OF THE RADIOACTIVE SPRINGS (XXIX) THE EFFECT OF FREQUENT THERMAL BATH ON BLOOD CATALASE
フルテキストURL 005_059_063.pdf
著者 森永 寛|
抄録 The author investigated the effect of frequent thermal bath on blood catalase in healthy persons, liver injured patients and rabbits. The blood catalase level of rabbits tends to increrease after a radioative thermal bath at a temperature of 42°-43℃ in " YAMADA-KU KYODO-YU " . but it tends to decrease after a thermal bath in the Labolatory, which Radon content is about one tenth of the former, namely 40-70×10(-10) Curie units per liter. By the repeated thermal baths of daily three times the blood catalase level of rabbit tends to fall lower after each bath. In healthy persons no remarkable change was shown in the initial blood catalase level by the frequent thermal baths of daily three times at 42°-43℃for 5 minutes. But in liver injured patients a gradual fall of initial level and a slow recovery were seen after each thermal bath.
出版物タイトル 岡山大学温泉研究所報告
発行日 1951-08
5巻
開始ページ 59
終了ページ 63
ISSN 0369-7142
関連URL http://eprints.lib.okayama-u.ac.jp/15926
言語 Japanese
論文のバージョン publisher
NAID 40017532397
JaLCDOI 10.18926/40170
タイトル(別表記) Study on the conbined therapy of spa and gold salt in rheumatoid arthritis Part II. An experience of granulocytopenia possibly caused by gold salt preparation
フルテキストURL pitsr_039_037_042.pdf
著者 池上 忠興| 八幡 隆昭| 北山 稔| 森永 寛|
抄録 A thirty seven years old woman with rheumatoid arthritis was instituted gold salt intramuscularly twice a week on the nineteenth hospital day. On the fifty fourth day, however, it was discontinued at the total dosis of 180 mg because of the skin rush. In about ten days after stopping gold injection appeared high fever with shivering and granulocytopenia was demonstrated. With immediate administration of ACTH, adrenocortical hormons etc. including blood transfusion the abnormal findings of the blood pictures returned to normal and the patient became well. Recently, gold salts are so widely used in treatment of rheumatoid arthritis as one of specific antirheumatic agents that the possible severe side effect such as granulocytopenia, if quite rare, should always be considered in the course of gold therapy.
出版物タイトル 岡山大学温泉研究所報告
発行日 1970-03-30
39巻
開始ページ 13
終了ページ 35
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
JaLCDOI 10.18926/40142
タイトル(別表記) A case of systemic lupus erythematosus with idiopathic thrombocytopenic purpura
フルテキストURL pitsr_042_025_029.pdf
著者 市川 幸延| 池上 忠興| 北山 稔| 森永 寛|
抄録 A 24-year-old woman was presented in whom thrombocytopenic purpura appeared during antiinflammatory drugs therapy for arthralgia. At that time she had a positive LE cell preparation, positive antinuclear factor and false positive serum test for syphilis. Steroid hormon and ACTH therapy were started under the diagnosis of systemic lupus erythematosus. In the 23-rd hospital days, she had a negative LE cell preparation, negative antinuclear factor and negative serum test for syphilis. In the 28-th days after stopping steroid hormon and ACTH therapy, positive LE cell preparation and positive antinuclear factor appeared again.
出版物タイトル 岡山大学温泉研究所報告
発行日 1973-03-25
42巻
開始ページ 25
終了ページ 29
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002398146
JaLCDOI 10.18926/21195
タイトル(別表記) The treatment of rheumatoid arthritis with D-penicillamine. Preliminary report
フルテキストURL pitsr_047_069_075.pdf
著者 石井 廣文| 高杉 潔| 北山 稔| 森永 寛|
抄録 Twenty patients with classical or definite rheumatoid arthritis were treated with D-Penicillamine. Favorable responses were observed in 75% of the patients. Significant improvement in clinical parameters, such as ESR, CRP, titers of rheumatoid factor and so forth, was noticed in twenty weeks of treatment. Withdrawal from penicillamine treatment was necessitated in four patients because of adverse reactions to the drug. Untoward effects included skin rash (most frequent), pruritis and loss of taste. From this preliminary study we presume that in earlier cases in which rheumatoid lesions may be reversible, more favorable clinical effects would be expected from this agent.
出版物タイトル 岡山大学温泉研究所報告
発行日 1978-03-25
47巻
開始ページ 69
終了ページ 75
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310960
JaLCDOI 10.18926/21180
タイトル(別表記) Determination of boron in thermal waters by emission spectrophotometry using "Spectraspan"
フルテキストURL pitsr_048_035_041.pdf
著者 御船 政明| 青木 宏子| 鉄本 潤子| 古野 勝志| 森永 寛|
抄録 A plasma emission spectrophotometer "Spectraspan" (low power d. c. plasma arc, operating on argon) was evaluated for boron determination in thermal waters. The influence of acids (hydrochloric, nitric and sulfuric acids) and several metallic ions (Na(+). K(+), Mg(2+). Ca(2+)) on emission intensity was studied. There was a linear relationship between emission intensity and boron content from 0 to 500 mg/l. Boron in thermal waters was easily determined by standard addition method. Precision. coefficient of variance and recoveries of known amount of boron added to the sample for 11 repricate analyses were 0.12μg/ml, 2.02%, 95.0-101.7%, respectively. Boron content of 27 thermal waters in the Sanin district was determined. and the highest B content in the sample waters were 8.8 mg/l (Tottori spa) in Tottori Prefecture and 14.6-25.0 mg/l (the thermal springs at the foot of Mt. Sanbe. a non-active quaternary volcano) in Shimane Prefecture. The relationships between B content and water temperature, B content and pH value were not recognized. Significantly positive correlationship was observed between Band Li contents.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
48巻
開始ページ 35
終了ページ 41
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311017
JaLCDOI 10.18926/21179
タイトル(別表記) Studies on sinter deposit Misasa radioactive hot springs
フルテキストURL pitsr_048_025_033.pdf
著者 古野 勝志| 鉄本 潤子| 青木 宏子| 御船 政明| 森永 寛| 福島 覚| 和田 洋明|
抄録 Sinter deposit in a distributing pipe used for about fifteen years in Misasa radioactive hot springs was investigated. The results were as follows; 1. The metal elements in this deposit were quaIi. tatively analysed by spectraspan plasma emission spectrophotometry (SPES), by fluorescent X-ray spectrometry, and following elements were detected; B, Na, Mg, AI, K, Ca, Mn, Fe, Cu, Zn, As, Sr, Ba and Pb. 2. The metal elements in this deposit were quantatively analysed by SPES and atomic absorption spectrophotometry, and following elements were determined; Fe : 508.7, As: 26.40, Ca: 7.85, Mn : 2.00, Al : 1.80, Na: 1.60, Zn: 1.33, K: 0.80, Cu: 0.67, Sr: 0.47, Mg: 0.35, Ba: 0.33 and B : 0.30 mg per gram. The color of this deposit was red brown, and the main component was ferric oxide. 3. Radioactive elements in this deposit were detected by autoradiography and radioluxography. Among the radioactive elements, concentration of radium was 320.5×10(-12)g/g (313.0×10(-12)Ci/g).
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-03-25
48巻
開始ページ 25
終了ページ 33
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310949
JaLCDOI 10.18926/21170
タイトル(別表記) General survey of the spa treatment at Misasa Spa (2nd report)
フルテキストURL pitsr_049_015_019.pdf
著者 森永 寛|
抄録 A general survey of the spa treatment at Misasa Spa carried out in February, 1979. The informations the author has gathered may be summarized as follows: 1. The majority of spa visitors was over 60 years old. 2. 47% of spa visitors came to this hot spring for rest and recreation, 43% for the purpose of balneotherapy of chronic rheumatic disorders and after-care. 3. Those who visited Misasa Spa for the first time were 32%, the rest being those who visited this spa over 2 times. 4. The length of time they stay at Misasa Spa for recreation was under 7 days, and for curative treatment was for about 2 weeks.
出版物タイトル 岡山大学温泉研究所報告
発行日 1979-09-25
49巻
開始ページ 15
終了ページ 19
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310935
JaLCDOI 10.18926/21149
タイトル(別表記) Studies on sinter deposits in Misasa radioactive hot springs (2nd report)
フルテキストURL pitsr_051_035_042.pdf
著者 古野 勝志| 御舩 政明| 森永 寛| 福島 覚| 和田 洋明|
抄録 Qualitative and quantitative analysis of sinter deposits in a distributing pipe used for seventeen years (Sample No.1) and adhere to bathtub wall for eleven years (Sample No.2 and Sample No.3) in Misasa radioactive hot springs were investigated. The results were as follows ; (1) The color of deposits of Sample No.1 and Sample No.2 was black and the color of deposits of Sample No.3 was white. The metal elements in these deposits were qualitative analysed by spectraspan plasma emission spectrophotometry (SPES) and by fluorescent X-ray spectrometry. Following elements were detected, in Sample No.1 : Na, Mg, Al, K, Ca, Mn, Fe, Cu, As, Sr, Ba, Mo, and Pb, in Sample No.2 : Na, Mg, Al, Si, K, Ca, Ti, Mn, Fe, Cu, Zn, As, Sr, Ba, Pb and Cl and in Sample No.3 : Na, Mg, Al, Si, K, Ca, Mn, Fe, Cu, Zn, As, Rb, Sr, Mo, Ba, S, and Cl, (2) The metal elements in these deposits were quantitative analysed by SPES, atomic absorption spectrophotometry and emission spectrophometry. Following elements were determined, in Sample No.1 ; Mn : 411.6, Fe : 65.7, Ba : 20.0, Ca : 11.9, Na : 5.7, Cu : 4.5, K : 4.2, Sr : 2.9, Zn : 2.6, Mg : 1.4, in Sample No.2 ; Mn : 248.2, Fe : 28.5, Ba : 15.6, Ca : 25.0, Mg : 10.5, Na : 9.3, Cu : 5.4, K : 4.9, Sr: 7.4, Zn : 3.3, and in Sample No.3 ; Ca : 275.2, Sr : 32.4, Mg: 12.4, Na: 18.7, K: 5.0, Mn: 1.7 and Fe: 0.6mg per gram. The main components of these deposits were manganese compounds (Sample No.1 and Sample No.2) and calcium compounds (Sample No.3). Qualitative and quantitative analysis of barium in sinter deposits of Misasa spa was done by authers for the first time. (3) Radioactivity in these deposits were observed by autoradiography. Among the radioactive elements, concentration of radium were 3.41×10(-8) Ci/g (Sample No.1), 4.70×10(-9) Ci/g (Sample No.2) anp 2.36×10(-11) Ci/g (Sample No.3), respectively.
出版物タイトル 岡山大学温泉研究所報告
発行日 1981-03-25
51巻
開始ページ 35
終了ページ 42
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311013
JaLCDOI 10.18926/21145
タイトル(別表記) Pulmonary lesions in rheumatoid arthritis-survey of chest radiographs in patients admitted with rheumatoid arthritis during last ten years
フルテキストURL pitsr_051_001_015.pdf
著者 谷崎 勝朗| 小田 康広| 田中 淳太郎| 駒越 春樹| 高杉 潔| 森永 寛| 原田 寛| 木村 郁郎|
抄録 Chest radiographs were examined in 147 patients with rheumatoid arthritis who were admitted at the Department ofInternal Medicine, Okayama University, Misasa Medical Branch during last ten years. The results were as follows. 1) Diffuse micronodular shadow on chest radiographs was shown in eighty nine out of 147 cases (60.5%), although the incidence of micronodular shadow was 47.3% in the other types except type 1, demonstrating the shadow limitted in the part of lower lung fields. The incidence in type 2 and 3, revealing micronodular shadow distributed over lung fields, was 22.4%. 2) The incidence of micronodular shadow was more frequently found in females than in males. The results obtained here was different from those previously reported. 3) The cases with type 2 and 3 tended to demonstrate a long duration of the desease, acceleration of ESR, positive rheumatoid factors, and elevation of serum γ-globulin and IgG levels, compared with the other types and cases without radiological findings. 4) Pulmonary lesions induced by treatment of gold or penicillamine were not recognized, except one suspected case with gold therapy.
出版物タイトル 岡山大学温泉研究所報告
発行日 1981-03-25
51巻
開始ページ 1
終了ページ 15
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310957
JaLCDOI 10.18926/21135
タイトル(別表記) Studies on Rat Peritoneal Mast Cells 2. Effect of BSA on Ca(2+) Uptake of Mast Cells
フルテキストURL pitsr_052_029_032.pdf
著者 谷崎 勝朗| 田中 淳太郎| 駒越 春樹| 森永 寛| 岸本 卓巳| 木村 郁郎| Townley Robert G.|
抄録 To examine the effect of BSA on the cell surface of mast cells, the (45)Ca influx was observed in mast cells from actively sensitized rats and also in cells passively sensitized with IgE-containing serum before or after purification by BSA. The mast cells from actively sensitized rats showed a marked increase in the (45)Ca uptake with stimulation by ovalbumin. The value of (45)Ca uptake by the cells was 1495 ± 104 cpm / 10(5) cells. The uptake of (45)Ca by mast cells passively sensitized before or after separation through BSA was also increased in response to ovalbumin, although the degree of 45Ca uptake by the latter showed marked variation. These results may suggest that BSA affects mast cell surface when the cells are sensitized after separation by BSA.
出版物タイトル 岡山大学温泉研究所報告
発行日 1982-03-25
52巻
開始ページ 29
終了ページ 32
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311041
JaLCDOI 10.18926/21134
タイトル(別表記) Studies on Rat Peritoneal Mast Cells 1. Purification of Mast Cells From Rat Peritoneal Cavity
フルテキストURL pitsr_052_023_028.pdf
著者 谷崎 勝朗| 田中 淳太郎| 駒越 春樹| 森永 寛| 岸本 卓巳| 木村 郁郎| Townley Robert G.|
抄録 To get a high recovery rate of mast cells from the rat peritoneal cavity, a new modified method was discussed using BSA density gradient. Three procedures, peritoneal lavage, washing of peritoneal cells and purification by BSA, were tested in this study, and the numbers of total cells and mast cells in each procedure were calculated. The recovery rate was the highest in BSA density gradient purification of the cells washed once with low speed centrifugation. The recovery rate was 73.7% and the number of mast cells taken from one rat was approximately 1.5×10(6). The purity of the cells with this procedure was 95.0% (range from 93.0 to 96.0%).
出版物タイトル 岡山大学温泉研究所報告
発行日 1982-03-25
52巻
開始ページ 23
終了ページ 28
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310940
JaLCDOI 10.18926/21124
タイトル(別表記) A case report of a patient with chronic pancreatitis successfully treated by endoscopic elimination of protein plugs
フルテキストURL pitsr_053_061_065.pdf
著者 武田 正彦| 田中 淳太郎| 高杉 潔| 原田 英雄| 万治 忠福| 森永 寛| 鶴見 哲也| 藤井 靖久|
抄録 Presented here is a case report of a 56 years old male patient with chronic pancreatitis in which a dramatic improvement in symptoms and objective findings were noted after endoscopic elimination of protein plugs. In September, 1979, he had an acute onset of pancreatitis followed by pseudocyst formation and the following combined operations were performed: resection of the pseudocyst, resection of the body and tail of the pancreas along with the spleen, partial resection of the stomach and the transverse colon, and gastroenterostomy according to Billroth I method. He had been followed up at out-patient clinic for chronic pancreatitis and diabetes until January 14,1979 when he was hospitalized for anorexia, loss of weight, pretibial edema, and upper-abdominal pain. The patient's condition was characterized by emaciation (height 152 cm, weight 37 kg), anemia (Hb 7.9g/dl), hypoproteinemia (serum protein 4.2 g/dl) , and hypolipidemia (total cholesterol 73 mg/dl). Abdominal ultrasound, abdominal CT and ERCP revealed stones in the pancreatic duct. Symptoms and objective findings were only partially improved by medical regimens. Subsequently we performed endoscopic cannulation of the pancreatic duct for elimination of pancreatic stones. Successful elimination of large numbers of protein plugs resulted in dramatic improvement of symptoms and objective findings. This procedure proved to add a new important tool in the treatment of chronic pancreatitis.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 61
終了ページ 65
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311007
JaLCDOI 10.18926/21122
タイトル(別表記) Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases
フルテキストURL pitsr_053_051_055.pdf
著者 周藤 真康| 駒越 春樹| 村嶋 誠| 岡田 千春| 谷崎 勝朗| 森永 寛| 塩田 雄太郎| 木村 郁郎|
抄録 Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 51
終了ページ 55
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002310967
JaLCDOI 10.18926/21121
タイトル(別表記) Clinical problems of long-term steroid regimen for bronchial asthma, with reference to steroid-dependent cases
フルテキストURL pitsr_053_045_049.pdf
著者 駒越 春樹| 周藤 真康| 岡田 千春| 谷崎 勝朗| 森永 寛| 貴谷 光| 合田 吉徳| 多田 慎也| 高橋 清| 木村 郁郎|
抄録 Adverse side effects of steroid therapy were investigated in 32 asthmatic patients. Thirty-two patients were classified into three groups according to steroid therapy for the past five years; group 1 has been treated with continuous steroid therapy, group 2 with occasional steroid therapy and group 3 without steroid therapy. The results were as follows. 1. Group 1 showed a low level of serum cortisol at 8-9 a. m. The serum concentration of cortisol in patients with daily steroid regimen was lower as compared to that in patients with alternateday steroid therapy. 2. The daily profile of serum cortisol was low in the steroid dependent asthmatic patients, and little increase of serum cortisol level after the administration of prednisolone was shown in group 1. 3. Serum IgG and IgM levels were significantly low in steroid dependent asthmatic patients. 4. The level of serum potassium was low in group 1.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 45
終了ページ 49
ISSN 0369-7142
言語 Japanese
論文のバージョン publisher
NAID 120002311040
JaLCDOI 10.18926/21119
タイトル(別表記) 好塩基球からのヒスタミン遊離に関する研究. 2. ハウスダスト抗原および抗ヒトIgEによるヒスタミン遊離
フルテキストURL pitsr_053_029_033.pdf
著者 谷崎 勝朗| 駒越 春樹| 周藤 真康| 御般 政明| 森永 寛| 貴谷 光| 合田 吉徳| 多田 慎也| 木村 郁郎|
抄録 IgE-mediated release of histamine from whole blood was examined in two healthy and four asthmatic subjects by dose-dependent fashion. The significantly increased amount of histamine was released from basophils of both healthy and asthmatic subjects by a limited concentration of anti-IgE. Antigen (house dust) caused histamine release only from basophils of asthmatics who are sensitive to house dust. Basophils from one patients with asthma released no significant amount of histamine by anti-IgE.
抄録(別表記) 好塩基球からのIgE-mediated histamine releaseの機序を,健康人(2名)および気管支喘息(4例)それぞれの代表例で比較検討した. 抗ヒトIgEの添加濃度別検討では,健康人および外因性喘息例いずれも有意のヒスタミン遊離の増加をしめしたが,Max. % histamine releaseをひきおこす抗ヒトIgEの濃度は比較的限られた範囲内にある傾向がみられた. 一方内因性喘息例では,いずれの抗ヒトIgE濃度でも有意のヒスタミン遊離はみられなかった. ハウスダスト抗原の添加濃度別検討では,ハウスダストが抗原である気管支喘息症例においてdose-dependentなヒスタミン遊離が観察されたが,使用された抗原濃度の範囲ではMax. % releaseをひきおこす至適濃度は明らかでなかった.
出版物タイトル 岡山大学温泉研究所報告
発行日 1983-03-25
53巻
開始ページ 29
終了ページ 33
ISSN 0369-7142
言語 English
論文のバージョン publisher
NAID 120002310980