ID | 17499 |
Eprint ID | 17499
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フルテキストURL | |
タイトル(別表記) | Effects of vaso-active peptides on the excitability of identified molluscan giant neurones
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著者 |
竹内 宏
岡山大学医学部附属脳代謝研究施設機能生化学部門
森 昭胤
岡山大学医学部附属脳代謝研究施設機能生化学部門
横井 功
岡山大学医学部附属脳代謝研究施設機能生化学部門
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抄録 | Two spontaneous firing giant neurones (TAN, tonically oscillating neurone and PON, periodically oscillating neurone) were identified in the subesophageal ganglia of Achatina fulica Ferussac. Effects of vaso-active peptides (substance P, physalaemin, eledoisin-related substance, neurotensin, bradykinin (B.K.), Lys-B.K., Met-Lys-B.K., angiotensin (A.G.) Ⅰ, A.G. Ⅱ, hypertensin, A.G. Ⅲ) were examined on the excitability of these two neurones. Physalaemin showed the excitatory effect on the TAN excitability. This effect was due to depolarizing the TAN neuromembrane. The critical concentration (in bath application) was about 5x10(-5)g/ml. All of amino acids, of which physalaemin consists, were ineffective on the TAN excitability. The other mentioned peptides than physalaemin were ineffective on the same neuromembrane. All of peptides examined in the present work were ineffective on the PON excitability. Effects of vaso-active peptides are considered to be selective in the neuronal level.
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発行日 | 1975-12-30
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 87巻
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号 | 11-12号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 949
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終了ページ | 953
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/87/11-12/87_11-12_949/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
Japanese
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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