このエントリーをはてなブックマークに追加
ID 17499
Eprint ID
17499
フルテキストURL
Thumnail 87_949.pdf 1.02 MB
タイトル(別表記)
Effects of vaso-active peptides on the excitability of identified molluscan giant neurones
著者
竹内 宏 岡山大学医学部附属脳代謝研究施設機能生化学部門
森 昭胤 岡山大学医学部附属脳代謝研究施設機能生化学部門
横井 功 岡山大学医学部附属脳代謝研究施設機能生化学部門
抄録
Two spontaneous firing giant neurones (TAN, tonically oscillating neurone and PON, periodically oscillating neurone) were identified in the subesophageal ganglia of Achatina fulica Ferussac. Effects of vaso-active peptides (substance P, physalaemin, eledoisin-related substance, neurotensin, bradykinin (B.K.), Lys-B.K., Met-Lys-B.K., angiotensin (A.G.) Ⅰ, A.G. Ⅱ, hypertensin, A.G. Ⅲ) were examined on the excitability of these two neurones. Physalaemin showed the excitatory effect on the TAN excitability. This effect was due to depolarizing the TAN neuromembrane. The critical concentration (in bath application) was about 5x10(-5)g/ml. All of amino acids, of which physalaemin consists, were ineffective on the TAN excitability. The other mentioned peptides than physalaemin were ineffective on the same neuromembrane. All of peptides examined in the present work were ineffective on the PON excitability. Effects of vaso-active peptides are considered to be selective in the neuronal level.
発行日
1975-12-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
87巻
11-12号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
949
終了ページ
953
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/87/11-12/87_11-12_949/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma