岡山医学会 Acta Medica Okayama 0030-1558 71 11-1 1959 味覚の臨床的研究 第1編 疾病に依る味覚閾値の変動 7389 7407 EN Kimiaki Honda The threshold value of taste was measured in 144 cases on the admission and the convalescent period with treatment. And the result were as follows. 1. On the attac of disease, the rate showing the threshold value over normal was high in ordor of the sweet, bitter, sour and salty taste. 2. As for the rising degree of threshold value over normal limit, many cases showed the slight rise of sweet, salty and sour taste and there were considerably many cases with the high rise of bitter taste. 3. As for the change of the threshold value of taste before and after the treatment, the salty and sour taste changesd within normal limit in many cases, the sweet and bitter teste showed abnormal threshold value before the treatment in pretty many cases. But the cases showing abnormal threshold value of the above 4 tastes before the treatment showed the returning tendency to normal threshold value after the treatment. 4. The resing degree of the threshold value of taste was different with eaoh disase, the sweet saste showed the high rise in dncdenal ulcer and hapatitis and it showed the slight rise in chronic gastritis and anemia. The cases with the rise of salt taste were few and the degree of rise was also slight, but there were many cases with the rise of salt taste in nephritis and heart failure. And there were few cases with the rise of salt taste in fever disease, out there were many cases with the high rise in the above cases. The rising degree of sour taste was slight in many cases, but there were many cases with the rise of the threshold value in livercirrhosis and high fever. The bitter teste showed considerably high rise, especially it was remarkable in stomach ulcer, liver disease, heart failure, and high fever. But it died not show in most of chronic gastritis and diabetes. 5. There were many cases showing the high threshold value in the cases with thick fur and it was thought that the multiplication of tongue papilla influenced upon the sweet taste. The remarkable change of threshold value was not observed on the cases with papillar atrophy and tongue fissure. 6. No fixed correlation between the colloidal reaction of liver function in liver disease and the threshold value of taste was observed. 7. The rise of the threshold value of bitter taste was observed on many cases with the decline of glomerular filtrating dosis in kidney disease, but the relation to the salt taste and other taste was not observed. No potential conflict of interest relevant to this article was reported.

岡山医学会 Acta Medica Okayama 0030-1558 71 11-1 1959 味覚の臨床的研究 第2編 血液含有物質，胃液酸度及び唾液pHと味覚との関係に就て 7409 7424 EN Kimiaki Honda The corrlation among the cotained substance in blood, the acidity of fastric fluid the pH of saliva and the taste was observe on the attacked paiod and convalescen pariod of disease. And the resulte were as follows. 1. Observing on the correlation between the dosis of serum sodium and the throshold value of taste, the threshold value of sweed taste showed the high value in many cases with the low value of serum sodium at the attacked period of disease and it showed the declining tendency with the increase of serum sodium by the recovery of disease. No fixed correlation between the dosis of serum sodium a d the salt, sour or bitter taste was observed. 2. The correlation between the dosis of serum chloride and the threshold value of saste was similar to that on the occasion of serum sodium. 3. As for the correlation between the dosis of serum potassium and the threshold value of taste, many cases with the high value of serum potassium at the attacked period of disease showed the high value of serum potassium at the attacked period of disease showed the high threshold value of sweet and bitter taste and they showed the returning tendency to normal value at the convalescent perio with normal value of serum potassioum. No fixed correlation between the dosis of serum potassium and the threshold value of salt or sour taste was observed. 4. As for the correlation bet ween the dosis of serum iron and the threshold value of taste, the threshold value of bitter taste showed the tendency taking the high value on the low value of serum iron. The tendency was especially remerkable in the patients with anemia. No fixed relation between the dosis of serum iron and the threshold value of sweet, salt or sour taste was not observed. 5. As for the correlation between the dosis of serum copper and the threshold value of taste, the theshold value of sweet and sour taste showed the tendency to declins, as the dosis of serum copper became decreased at the attaked period of disease in many cases. And they showed the tendency to decline with the decrease of serum copper at the convalescent period, but no fixed correlation between the desis of rerum copper and the threshold value of salt or bitter taste. 6. The correlation between the increase or decrease of blood sugar at the hunger time and the rise of decline of the threshold value of sweet or sour taste was observed on various diseases, other than diabetes, In diabetes, the threshold value of sweet taste at the hunger time showeed the high valun, but no fixed correlation between the blood sugar at the hunger time and the threshold value of salt or bitter taste was observed. 7. No fixed correlation among the dosis of serum protein, the acidity of gastric fluid, the pH of saliva the threshold value of taste was observed. No potential conflict of interest relevant to this article was reported.