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ID 19181
Eprint ID
19181
フルテキストURL
Thumnail 71_779.pdf 385 KB
タイトル(別表記)
Studies on Brain Hexokinase. Part Ⅰ. On hexokinase in the cerebral cortex of rabbits
著者
山田 孝彦 岡山大学医学部第1(陣内)外科教室
抄録
The hexokinase activity in the cerebral cortex of normal rabbits was measured by Longs method and the influences of fluoride, Ca ion, glutamic acid, glutamine, aspartic acid, asparagine, γ-aminobutyric acid and α-ketoglutaric acid upon the hexokinase activity were also evaluated. The results were as follows: 1) The fluoride shows the maximum inhibition to the hexokinase activity at 0.5M of its concentration, and the inhibition rather decreases at higher concentration. 2) Ca ion shows an increasing inhibition as its concentration increases. 3) When asparagine or glutamic acid is added, the activity is markedly accelerated. 4) γ-Aminobutyric acid accelerates slightly the activity of the cerebral hexokinase and markedly that of the heart muscle hexokinase. 5) α-Ketoglutaric acid markedly inhibits the activity.
発行日
1959-02-28
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
71巻
2-2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
779
終了ページ
784
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/71/2-2/71_2-2_779/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma