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ID 42813
フルテキストURL
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タイトル(別表記)
Histology of the brain of rabbits with chronic local cerebral anaphylaxis
著者
坂井 邦典 岡山大学医学部第一(陣内)外科教室
抄録
The cow sera with phosphatid obtained from the cerebral gray matter, of cows were given in the ear vein of adult rabbits for 2cc per kg as antigen. As effective injection, 1cc per kg of diluted antigen, namely 4 and 6 times diluted solution of antigen was given every 4 days for 3-10 months in their ear vein. Thus the chronic local cerebral anaphylactic rabbits were made. And the motor area, frontal lobe, nucleus lenticularis, substantia nigra, Ammon's horn and pia mater were histologically researched. After repeated effective injections for a long time, the disappearance, disturbance of arrangement, atrophy, edematous degeneration, glial involvement and neuronophagia etc. of nerve cells, striking gliosis, disappearance and swelling of the sheath, hypertrophy of the wall of vessels, increase of wall cells, dilatation of lymphatic cavity surrounding the vessel adventitium, hypertrophy of pia mater and proliferation of connective tissue cells etc, were found. It would appear that, by repeating effective injections with diluted antigen for a longtime, the chronic local cerebral anaphylactic rabbits were made, and the histological findings of their brains were similar to those which were found in the brain of old idiopathic epilepsy.
発行日
1955-02-28
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
67巻
2号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
403
終了ページ
428
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/67/2/67_2_403/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
Copyright© 岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma