このエントリーをはてなブックマークに追加
ID 32819
JaLCDOI
フルテキストURL
著者
Okamoto, Osamu Okayama University
Yamamoto, Yuji Okayama University
Inagaki, Sachiyo Okayama University
Yoshitome, Kei Okayama University
ishikawa, Takaki Okayama University
Imabayashi, Kiyomi Okayama University
Miyaishi, Satoru Okayama University
Ishizu, Hideo Okayama University
抄録

Allele and genotype frequencies for 15 short tandem repeat (STR) polymorphisms--D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX and FGA--in a Japanese population were estimated. No deviations of the observed allele frequency from Hardy-Weinberg equilibrium expectations were found for any of the systems studied. Between 2 new pentanucleotide STR loci, Penta E and Penta D, for which there is only limited data regarding the allelic distribution in Japanese, the Penta E locus was found to be highly polymorphic and exhibited a tri- or tetra-modal distribution pattern having allelic peaks with 5, 11, 15 and 20 repeats. The distribution was significantly different from that of the other ethnic groups. Statistical parameters of forensic importance, the power of discrimination (PD), observed and expected heterozygosity values (H), polymorphism information content (PIC), power of discrimination (PD), matching probability (pM), power of exclusion (PE), and typical paternity index (PI), were calculated for the loci. These parameters indicated the usefulness of the loci in forensic personal identification and paternity testing among Japanese. The systems Penta E, FGA, D18S51 and D8S1179 were the most informative. This method was successfully applied to forensic personal identification and paternity testing among Japanese, thereby confirming its efficacy for forensic practice.

キーワード
population data
DNA typing
short tandem repests
personal identification
paternity testing
Amo Type
Article
発行日
2003-04
出版物タイトル
Acta Medica Okayama
57巻
2号
出版者
Okayama University Medical School
開始ページ
59
終了ページ
71
ISSN
0386-300X
NCID
AA00508441
資料タイプ
学術雑誌論文
言語
English
論文のバージョン
publisher
査読
有り
PubMed ID
Web of Sience KeyUT