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ID 17366
Eprint ID
17366
フルテキストURL
Thumnail 87_271.pdf 373 KB
タイトル(別表記)
Cellular Immunity of Mice Bearing Ehrlich Cancer Ⅱ. Time- Lapse Changes in Antitumor Activity of Lymphatic Tissues at Various Sites After Tumor Removal
著者
友保 敏 岡山大学医学部第一外科教室
抄録
For the purpose to elucidate changes in common immunity of cancer-bearing body after tumor removal, after transplanting 500×10(4) cells/mouse of Ehrlich ascites tumor cells to the back between the scapulae of DD mice, tumors were removed with lapse of time as thoroughly as possible, and on the 23 rd day of tumor transplantation regional axillary lymph nodes, distant mesenterial lymph nodes and spleen were removed and lymph node cells were prepared from them and these cells were tested for their antitumor activity to JTC-11 cells (derived from Ehrlich cancer cell). The results are briefly summarized as follows: 1. In the group removed of tumors on the seventh day after Ehrlich cancer transplantation none of the tissues showed antitumor activity. 2. In the group removed of tumors on the tenth day there was observed a strong antitumor activity remaining only in the regional lymph nodes. 3. In the group removed of tumors on the fifteenth day, antitumor activity was found in practically all lymphatic tissues inclusive of regional lymph nodes. 4. In the group removed of tumors on the 20th day, antitumor activity could be observed in none of the lymphatic tissues. Considering the antitiumor activity of lymphocytes from the aspect of common immunity in cancer-bearing body, when tumor mass is removed as thoroughly as possible at the time when there is sufficient antitumor activity, such an activity remains in the body for a long time after tumor removal.
発行日
1975-04-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
87巻
3-4号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
271
終了ページ
278
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/87/3-4/87_3-4_271/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma